Motif ID: Hmbox1

Z-value: 0.644


Transcription factors associated with Hmbox1:

Gene SymbolEntrez IDGene Name
Hmbox1 ENSMUSG00000021972.8 Hmbox1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmbox1mm10_v2_chr14_-_64949838_64949886-0.322.6e-01Click!


Activity profile for motif Hmbox1.

activity profile for motif Hmbox1


Sorted Z-values histogram for motif Hmbox1

Sorted Z-values for motif Hmbox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmbox1

PNG image of the network

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Top targets:


Showing 1 to 20 of 124 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_169685191 3.467 ENSMUST00000112104.1
ENSMUST00000112107.1
 Mid1

midline 1

chrX_+_169879596 2.487 ENSMUST00000112105.1
ENSMUST00000078947.5
 Mid1

midline 1

chr13_-_41273977 1.352 ENSMUST00000163881.1
 Gm17364
predicted gene, 17364
chr3_+_118433797 1.105 ENSMUST00000180593.1
ENSMUST00000181926.1
ENSMUST00000181060.1
ENSMUST00000181310.1
 Gm26871



predicted gene, 26871



chr1_-_152386675 0.987 ENSMUST00000015124.8
 Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr1_-_75278345 0.922 ENSMUST00000039534.4
 Resp18
regulated endocrine-specific protein 18
chr12_+_36314160 0.859 ENSMUST00000041407.5
 Sostdc1
sclerostin domain containing 1
chr4_+_152338619 0.808 ENSMUST00000030775.5
ENSMUST00000164662.1
 Chd5

chromodomain helicase DNA binding protein 5

chr4_+_152338887 0.786 ENSMUST00000005175.4
 Chd5
chromodomain helicase DNA binding protein 5
chr10_+_112271123 0.744 ENSMUST00000092175.2
 Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr1_-_152386589 0.723 ENSMUST00000162371.1
 Tsen15
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr10_-_49783259 0.693 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
 Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr4_+_117252010 0.675 ENSMUST00000125943.1
ENSMUST00000106434.1
 Tmem53

transmembrane protein 53

chr15_-_58034289 0.574 ENSMUST00000100655.3
 9130401M01Rik
RIKEN cDNA 9130401M01 gene
chr2_+_3770673 0.531 ENSMUST00000177037.1
 Fam107b
family with sequence similarity 107, member B
chr15_-_79285502 0.521 ENSMUST00000165408.1
 Baiap2l2
BAI1-associated protein 2-like 2
chr6_+_29853746 0.515 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
 Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr11_-_95041335 0.507 ENSMUST00000038431.7
 Pdk2
pyruvate dehydrogenase kinase, isoenzyme 2
chr5_-_136565432 0.476 ENSMUST00000176172.1
 Cux1
cut-like homeobox 1
chr3_-_116711820 0.453 ENSMUST00000153108.1
 Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 6.0 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.1 1.7 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.3 1.6 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.9 GO:0060648 mammary gland bud morphogenesis(GO:0060648)
0.1 0.7 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.1 0.7 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 0.5 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.5 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.5 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.1 0.4 GO:2000668 dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
0.1 0.4 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.0 0.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.4 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.3 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.3 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.2 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)

Gene overrepresentation in cellular_component category:

Showing 1 to 19 of 19 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.2 GO:0005874 microtubule(GO:0005874)
0.1 1.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2 0.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.7 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.7 GO:0030673 axolemma(GO:0030673)
0.2 0.5 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 0.5 GO:0071439 clathrin complex(GO:0071439)
0.1 0.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.4 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.0 0.3 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.1 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.1 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0030877 beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.9 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.3 1.7 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.1 0.7 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 0.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.5 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.2 GO:0070052 collagen V binding(GO:0070052)
0.0 0.2 GO:0016783 sulfurtransferase activity(GO:0016783)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.1 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.0 0.1 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)