Motif ID: Hmga1

Z-value: 1.374


Transcription factors associated with Hmga1:

Gene SymbolEntrez IDGene Name
Hmga1 ENSMUSG00000046711.9 Hmga1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga1mm10_v2_chr17_+_27556641_275566580.733.2e-03Click!


Activity profile for motif Hmga1.

activity profile for motif Hmga1


Sorted Z-values histogram for motif Hmga1

Sorted Z-values for motif Hmga1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_19001099 5.477 ENSMUST00000040153.8
ENSMUST00000112828.1
 Rorb

RAR-related orphan receptor beta

chr12_-_108003594 3.918 ENSMUST00000066060.4
 Bcl11b
B cell leukemia/lymphoma 11B
chr6_-_59024340 3.496 ENSMUST00000173193.1
 Fam13a
family with sequence similarity 13, member A
chr6_-_59024470 2.739 ENSMUST00000089860.5
 Fam13a
family with sequence similarity 13, member A
chr6_-_102464667 2.731 ENSMUST00000032159.6
 Cntn3
contactin 3
chr3_+_67892189 2.673 ENSMUST00000063263.3
 Iqcj
IQ motif containing J
chr1_-_52490736 2.626 ENSMUST00000170269.1
 Nab1
Ngfi-A binding protein 1
chr8_-_87959560 2.584 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr9_-_90255927 2.450 ENSMUST00000144646.1
 Tbc1d2b
TBC1 domain family, member 2B
chr6_+_88724828 2.427 ENSMUST00000089449.2
 Mgll
monoglyceride lipase
chr6_-_99044414 2.359 ENSMUST00000177507.1
ENSMUST00000123992.1
 Foxp1

forkhead box P1

chr6_-_99028874 2.290 ENSMUST00000154163.2
 Foxp1
forkhead box P1
chr5_-_66514815 2.222 ENSMUST00000161879.1
ENSMUST00000159357.1
 Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr2_-_140671440 2.186 ENSMUST00000099301.1
 Flrt3
fibronectin leucine rich transmembrane protein 3
chr18_-_43059418 2.184 ENSMUST00000025377.7
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr1_-_158814469 2.183 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr18_-_62741387 2.048 ENSMUST00000097557.3
 Spink13
serine peptidase inhibitor, Kazal type 13
chr19_-_57197435 1.993 ENSMUST00000111550.1
 Ablim1
actin-binding LIM protein 1
chr15_-_103215285 1.984 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
 Cbx5


chromobox 5


chr6_-_99435345 1.967 ENSMUST00000113322.2
ENSMUST00000176850.1
ENSMUST00000176632.1
 Foxp1


forkhead box P1



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 115 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 6.6 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.9 5.5 GO:0046549 retinal cone cell development(GO:0046549)
1.8 5.4 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.0 4.2 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 4.1 GO:0036075 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)
0.7 3.9 GO:0021773 striatal medium spiny neuron differentiation(GO:0021773)
0.2 3.3 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.5 2.9 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.1 2.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.1 2.5 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.3 2.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 2.4 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 2.4 GO:0030100 regulation of endocytosis(GO:0030100)
0.1 2.3 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.3 2.2 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.0 2.2 GO:0060349 bone morphogenesis(GO:0060349)
0.0 2.2 GO:0030048 actin filament-based movement(GO:0030048)
0.0 2.1 GO:0007266 Rho protein signal transduction(GO:0007266)
0.7 2.0 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938)
0.4 2.0 GO:0060467 negative regulation of fertilization(GO:0060467)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.4 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.1 3.9 GO:0044295 axonal growth cone(GO:0044295)
0.1 2.9 GO:0071565 nBAF complex(GO:0071565)
0.1 2.6 GO:0097440 apical dendrite(GO:0097440)
0.2 2.4 GO:0043196 varicosity(GO:0043196)
0.1 2.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 2.0 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 2.0 GO:0010369 chromocenter(GO:0010369)
0.0 1.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.6 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 1.4 GO:0071439 clathrin complex(GO:0071439)
0.1 1.3 GO:0070852 cell body fiber(GO:0070852)
0.0 1.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 1.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.4 1.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.2 1.1 GO:0070826 paraferritin complex(GO:0070826)
0.1 1.0 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.8 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
1.8 5.5 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 5.4 GO:0003779 actin binding(GO:0003779)
0.2 5.3 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 3.5 GO:0005096 GTPase activator activity(GO:0005096)
0.4 2.9 GO:0001618 virus receptor activity(GO:0001618)
0.2 2.9 GO:0017166 vinculin binding(GO:0017166)
0.1 2.5 GO:0001540 beta-amyloid binding(GO:0001540)
0.2 2.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 2.4 GO:0035064 methylated histone binding(GO:0035064)
0.0 2.4 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 2.3 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.1 2.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.1 1.6 GO:0002162 dystroglycan binding(GO:0002162)
0.0 1.5 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.3 1.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.1 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.2 GO:0043495 protein anchor(GO:0043495)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)