Motif ID: Hmga2

Z-value: 1.966


Transcription factors associated with Hmga2:

Gene SymbolEntrez IDGene Name
Hmga2 ENSMUSG00000056758.8 Hmga2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga2mm10_v2_chr10_-_120476469_120476527-0.107.3e-01Click!


Activity profile for motif Hmga2.

activity profile for motif Hmga2


Sorted Z-values histogram for motif Hmga2

Sorted Z-values for motif Hmga2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga2

PNG image of the network

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Top targets:


Showing 1 to 20 of 117 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_98667264 13.697 ENSMUST00000099683.1
 Gm10800
predicted gene 10800
chr9_+_3013140 13.200 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr14_-_19418930 11.931 ENSMUST00000177817.1
 Gm21738
predicted gene, 21738
chr9_+_3004457 9.599 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3023547 8.659 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3025417 8.073 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr9_+_3017408 6.936 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3018753 6.599 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr2_+_158375638 2.962 ENSMUST00000109488.1
 Snhg11
small nucleolar RNA host gene 11
chr11_+_82035569 2.157 ENSMUST00000000193.5
 Ccl2
chemokine (C-C motif) ligand 2
chr5_+_21372642 1.986 ENSMUST00000035799.5
 Fgl2
fibrinogen-like protein 2
chr13_-_62607499 1.839 ENSMUST00000091563.4
 6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr16_-_43979050 1.749 ENSMUST00000165648.1
ENSMUST00000036321.7
 Zdhhc23

zinc finger, DHHC domain containing 23

chr10_+_123264076 1.537 ENSMUST00000050756.7
 Fam19a2
family with sequence similarity 19, member A2
chr3_+_53845086 1.527 ENSMUST00000108014.1
 Gm10985
predicted gene 10985
chr9_-_123260776 1.394 ENSMUST00000068140.4
 Tmem158
transmembrane protein 158
chr11_-_102897123 1.331 ENSMUST00000067444.3
 Gfap
glial fibrillary acidic protein
chr19_-_11818806 1.309 ENSMUST00000075304.6
 Stx3
syntaxin 3
chr4_+_130913120 1.276 ENSMUST00000151698.1
 Laptm5
lysosomal-associated protein transmembrane 5
chr4_+_44756553 1.111 ENSMUST00000107824.2
 Zcchc7
zinc finger, CCHC domain containing 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.4 GO:0019835 cytolysis(GO:0019835)
0.5 2.2 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.3 1.9 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.1 1.7 GO:0018345 protein palmitoylation(GO:0018345)
0.0 1.5 GO:0001578 microtubule bundle formation(GO:0001578)
0.2 1.3 GO:0016081 synaptic vesicle docking(GO:0016081)
0.4 1.2 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.3 1.0 GO:0016598 protein arginylation(GO:0016598)
0.3 0.9 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.2 0.9 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537)
0.1 0.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 0.8 GO:0032929 negative regulation of macrophage derived foam cell differentiation(GO:0010745) negative regulation of superoxide anion generation(GO:0032929)
0.1 0.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.8 GO:1900153 regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900151) positive regulation of nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay(GO:1900153)
0.0 0.8 GO:0031100 organ regeneration(GO:0031100)
0.1 0.7 GO:0072488 ammonium transmembrane transport(GO:0072488)
0.1 0.6 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.6 GO:0071425 hematopoietic stem cell proliferation(GO:0071425)
0.0 0.6 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.2 0.5 GO:0048388 endosomal lumen acidification(GO:0048388)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 2.2 GO:0044299 C-fiber(GO:0044299)
0.0 2.0 GO:0070469 respiratory chain(GO:0070469)
0.5 1.9 GO:0097450 astrocyte end-foot(GO:0097450)
0.3 1.3 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 1.2 GO:0005811 lipid particle(GO:0005811)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.7 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.4 GO:0030134 multivesicular body(GO:0005771) ER to Golgi transport vesicle(GO:0030134)
0.1 0.3 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.1 GO:0005940 septin ring(GO:0005940)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 2.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 1.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.3 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 1.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 0.9 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.9 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.2 0.8 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.8 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.7 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.5 GO:0015250 water channel activity(GO:0015250)
0.0 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.4 GO:0071568 UFM1 transferase activity(GO:0071568)
0.1 0.4 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.0 0.4 GO:0005537 mannose binding(GO:0005537)
0.0 0.4 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 0.3 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.2 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)