Motif ID: Hmx1

Z-value: 0.838


Transcription factors associated with Hmx1:

Gene SymbolEntrez IDGene Name
Hmx1 ENSMUSG00000067438.3 Hmx1



Activity profile for motif Hmx1.

activity profile for motif Hmx1


Sorted Z-values histogram for motif Hmx1

Sorted Z-values for motif Hmx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_+_11984581 2.068 ENSMUST00000170672.2
ENSMUST00000023138.7
 Shisa9

shisa homolog 9 (Xenopus laevis)

chr2_-_162661075 1.452 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
 Ptprt



protein tyrosine phosphatase, receptor type, T



chrX_-_166585679 1.443 ENSMUST00000000412.2
 Egfl6
EGF-like-domain, multiple 6
chr15_-_85578070 1.427 ENSMUST00000109424.2
 Wnt7b
wingless-related MMTV integration site 7B
chr19_-_14598031 1.353 ENSMUST00000167776.2
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr19_-_14597983 1.349 ENSMUST00000052011.7
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr1_+_34005872 1.328 ENSMUST00000182296.1
 Dst
dystonin
chr15_-_13173607 1.305 ENSMUST00000036439.4
 Cdh6
cadherin 6
chr6_+_58831456 1.285 ENSMUST00000141600.1
ENSMUST00000122981.1
 Herc3

hect domain and RLD 3

chr4_+_116221689 1.243 ENSMUST00000106490.2
 Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr4_+_94556546 1.230 ENSMUST00000094969.1
 Gm10306
predicted gene 10306
chr13_+_91461050 1.223 ENSMUST00000004094.8
ENSMUST00000042122.8
 Ssbp2

single-stranded DNA binding protein 2

chr4_+_116221590 1.216 ENSMUST00000147292.1
 Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr2_+_168081004 1.160 ENSMUST00000052125.6
 Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr6_-_148444336 1.091 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr8_+_83389878 1.050 ENSMUST00000109831.2
 Clgn
calmegin
chr15_+_60822947 1.016 ENSMUST00000180730.1
 9930014A18Rik
RIKEN cDNA 9930014A18 gene
chr17_+_8340710 0.960 ENSMUST00000163887.1
 Prr18
proline rich region 18
chr8_+_83389846 0.951 ENSMUST00000002259.6
 Clgn
calmegin
chr11_-_119547744 0.936 ENSMUST00000026670.4
 Nptx1
neuronal pentraxin 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 85 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 3.0 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)
0.0 2.4 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 2.1 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 2.0 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.1 1.7 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 1.6 GO:0016601 Rac protein signal transduction(GO:0016601)
0.5 1.4 GO:0072070 establishment or maintenance of polarity of embryonic epithelium(GO:0016332) loop of Henle development(GO:0072070) metanephric loop of Henle development(GO:0072236)
0.0 1.4 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.2 1.0 GO:0001778 plasma membrane repair(GO:0001778)
0.0 1.0 GO:0032526 response to retinoic acid(GO:0032526)
0.3 0.9 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865)
0.2 0.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.7 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.7 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.2 0.6 GO:0032439 endosome localization(GO:0032439)
0.1 0.6 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.1 0.6 GO:0050716 positive regulation of interleukin-1 secretion(GO:0050716) positive regulation of interleukin-1 beta secretion(GO:0050718)
0.1 0.6 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.9 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.2 2.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.3 1.3 GO:0031673 H zone(GO:0031673)
0.1 1.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.2 1.0 GO:0097513 myosin II filament(GO:0097513)
0.1 0.7 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.7 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0031430 M band(GO:0031430)
0.1 0.6 GO:0045179 apical cortex(GO:0045179)
0.0 0.6 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.5 GO:0071203 WASH complex(GO:0071203)
0.0 0.5 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0031901 early endosome membrane(GO:0031901)
0.1 0.4 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.4 GO:0032444 activin responsive factor complex(GO:0032444)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.4 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.4 GO:0031428 box C/D snoRNP complex(GO:0031428)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 3.0 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 2.8 GO:0070491 repressing transcription factor binding(GO:0070491)
0.1 2.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.9 GO:0030165 PDZ domain binding(GO:0030165)
0.1 1.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.4 1.4 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.0 1.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.3 0.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 0.8 GO:0004645 phosphorylase activity(GO:0004645)
0.1 0.8 GO:0001972 retinoic acid binding(GO:0001972)
0.2 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 0.7 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.7 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.2 0.6 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.6 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.1 0.6 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)