Motif ID: Hmx3

Z-value: 0.572


Transcription factors associated with Hmx3:

Gene SymbolEntrez IDGene Name
Hmx3 ENSMUSG00000040148.5 Hmx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx3mm10_v2_chr7_+_131542867_1315428670.411.5e-01Click!


Activity profile for motif Hmx3.

activity profile for motif Hmx3


Sorted Z-values histogram for motif Hmx3

Sorted Z-values for motif Hmx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx3

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 54 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_-_92131494 1.910 ENSMUST00000099326.3
ENSMUST00000146492.1
 Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr4_+_154960915 1.588 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr4_+_144893127 1.500 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr1_-_190170671 1.282 ENSMUST00000175916.1
 Prox1
prospero-related homeobox 1
chr18_+_61639542 1.146 ENSMUST00000183083.1
ENSMUST00000183087.1
 Gm20748

predicted gene, 20748

chr15_+_9436028 1.043 ENSMUST00000042360.3
 Capsl
calcyphosine-like
chr9_-_123678782 1.042 ENSMUST00000170591.1
ENSMUST00000171647.1
 Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr10_+_106470281 0.982 ENSMUST00000029404.9
ENSMUST00000169303.1
 Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr9_-_123678873 0.929 ENSMUST00000040960.6
 Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr5_-_137684665 0.918 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
 Agfg2


ArfGAP with FG repeats 2


chr14_-_55560340 0.777 ENSMUST00000066106.3
 A730061H03Rik
RIKEN cDNA A730061H03 gene
chr3_+_109573907 0.747 ENSMUST00000106576.2
 Vav3
vav 3 oncogene
chrM_+_9452 0.735 ENSMUST00000082411.1
 mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chrM_+_3906 0.667 ENSMUST00000082396.1
 mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr3_-_49757257 0.540 ENSMUST00000035931.7
 Pcdh18
protocadherin 18
chr2_-_153015331 0.456 ENSMUST00000028972.8
 Pdrg1
p53 and DNA damage regulated 1
chr12_+_38781093 0.408 ENSMUST00000161513.1
 Etv1
ets variant gene 1
chr3_+_62419668 0.404 ENSMUST00000161057.1
 Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr4_-_62470868 0.381 ENSMUST00000135811.1
ENSMUST00000120095.1
ENSMUST00000030087.7
ENSMUST00000107452.1
ENSMUST00000155522.1
 Wdr31




WD repeat domain 31




chr4_-_45532470 0.377 ENSMUST00000147448.1
 Shb
src homology 2 domain-containing transforming protein B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 2.9 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
0.3 2.0 GO:0036233 glycine import(GO:0036233)
0.1 1.9 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 1.5 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.7 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.7 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.1 0.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.3 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.1 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.4 GO:0070469 respiratory chain(GO:0070469)
0.0 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)

Gene overrepresentation in molecular_function category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.0 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 1.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.2 1.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)