Motif ID: Hmx3

Z-value: 0.572


Transcription factors associated with Hmx3:

Gene SymbolEntrez IDGene Name
Hmx3 ENSMUSG00000040148.5 Hmx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx3mm10_v2_chr7_+_131542867_1315428670.411.5e-01Click!


Activity profile for motif Hmx3.

activity profile for motif Hmx3


Sorted Z-values histogram for motif Hmx3

Sorted Z-values for motif Hmx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_92131494 1.910 ENSMUST00000099326.3
ENSMUST00000146492.1
 Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr4_+_154960915 1.588 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr4_+_144893127 1.500 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr1_-_190170671 1.282 ENSMUST00000175916.1
 Prox1
prospero-related homeobox 1
chr18_+_61639542 1.146 ENSMUST00000183083.1
ENSMUST00000183087.1
 Gm20748

predicted gene, 20748

chr15_+_9436028 1.043 ENSMUST00000042360.3
 Capsl
calcyphosine-like
chr9_-_123678782 1.042 ENSMUST00000170591.1
ENSMUST00000171647.1
 Slc6a20a

solute carrier family 6 (neurotransmitter transporter), member 20A

chr10_+_106470281 0.982 ENSMUST00000029404.9
ENSMUST00000169303.1
 Ppfia2

protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2

chr9_-_123678873 0.929 ENSMUST00000040960.6
 Slc6a20a
solute carrier family 6 (neurotransmitter transporter), member 20A
chr5_-_137684665 0.918 ENSMUST00000100544.4
ENSMUST00000031736.9
ENSMUST00000151839.1
 Agfg2


ArfGAP with FG repeats 2


chr14_-_55560340 0.777 ENSMUST00000066106.3
 A730061H03Rik
RIKEN cDNA A730061H03 gene
chr3_+_109573907 0.747 ENSMUST00000106576.2
 Vav3
vav 3 oncogene
chrM_+_9452 0.735 ENSMUST00000082411.1
 mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chrM_+_3906 0.667 ENSMUST00000082396.1
 mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr3_-_49757257 0.540 ENSMUST00000035931.7
 Pcdh18
protocadherin 18
chr2_-_153015331 0.456 ENSMUST00000028972.8
 Pdrg1
p53 and DNA damage regulated 1
chr12_+_38781093 0.408 ENSMUST00000161513.1
 Etv1
ets variant gene 1
chr3_+_62419668 0.404 ENSMUST00000161057.1
 Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr4_-_62470868 0.381 ENSMUST00000135811.1
ENSMUST00000120095.1
ENSMUST00000030087.7
ENSMUST00000107452.1
ENSMUST00000155522.1
 Wdr31




WD repeat domain 31




chr4_-_45532470 0.377 ENSMUST00000147448.1
 Shb
src homology 2 domain-containing transforming protein B
chr1_+_165788681 0.354 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
 Cd247



CD247 antigen



chr7_-_30559828 0.312 ENSMUST00000108164.1
 Lin37
lin-37 homolog (C. elegans)
chr5_-_87482258 0.285 ENSMUST00000079811.6
ENSMUST00000144144.1
 Ugt2a1

UDP glucuronosyltransferase 2 family, polypeptide A1

chr13_+_23746734 0.268 ENSMUST00000099703.2
 Hist1h2bb
histone cluster 1, H2bb
chr7_+_3645267 0.257 ENSMUST00000038913.9
 Cnot3
CCR4-NOT transcription complex, subunit 3
chr11_+_114668524 0.254 ENSMUST00000106602.3
ENSMUST00000077915.3
ENSMUST00000106599.1
ENSMUST00000082092.4
 Rpl38



ribosomal protein L38



chr7_-_30559600 0.254 ENSMUST00000043975.4
ENSMUST00000156241.1
 Lin37

lin-37 homolog (C. elegans)

chr6_+_86371489 0.234 ENSMUST00000089558.5
 Snrpg
small nuclear ribonucleoprotein polypeptide G
chr17_-_57247632 0.232 ENSMUST00000005975.6
 Gpr108
G protein-coupled receptor 108
chr5_+_15516489 0.206 ENSMUST00000178227.1
 Gm21847
predicted gene, 21847
chr19_-_41933276 0.206 ENSMUST00000075280.4
ENSMUST00000112123.2
 Exosc1

exosome component 1

chr7_-_45510400 0.203 ENSMUST00000033096.7
 Nucb1
nucleobindin 1
chr11_+_103133333 0.187 ENSMUST00000124928.1
ENSMUST00000062530.4
 Hexim2

hexamethylene bis-acetamide inducible 2

chr3_-_154328634 0.154 ENSMUST00000167744.1
 Lhx8
LIM homeobox protein 8
chr19_+_11965817 0.145 ENSMUST00000025590.9
 Osbp
oxysterol binding protein
chr8_-_23237623 0.142 ENSMUST00000033950.5
 Gins4
GINS complex subunit 4 (Sld5 homolog)
chr7_+_25681158 0.140 ENSMUST00000108403.3
 B9d2
B9 protein domain 2
chr11_+_103133303 0.136 ENSMUST00000107037.1
 Hexim2
hexamethylene bis-acetamide inducible 2
chr11_+_69838514 0.121 ENSMUST00000133967.1
ENSMUST00000094065.4
 Tmem256

transmembrane protein 256

chr19_+_41933464 0.116 ENSMUST00000026154.7
 Zdhhc16
zinc finger, DHHC domain containing 16
chr7_+_25267669 0.115 ENSMUST00000169266.1
 Cic
capicua homolog (Drosophila)
chr2_+_130424321 0.106 ENSMUST00000128994.1
ENSMUST00000028900.9
 Vps16

vacuolar protein sorting 16 (yeast)

chr10_+_115569986 0.104 ENSMUST00000173620.1
 A930009A15Rik
RIKEN cDNA A930009A15 gene
chr7_+_24370255 0.088 ENSMUST00000171904.1
 Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr3_+_66985947 0.085 ENSMUST00000161726.1
ENSMUST00000160504.1
 Rsrc1

arginine/serine-rich coiled-coil 1

chr12_+_108179738 0.082 ENSMUST00000101055.4
 Ccnk
cyclin K
chr12_-_108179237 0.057 ENSMUST00000071095.7
 Setd3
SET domain containing 3
chr14_+_54464141 0.038 ENSMUST00000022782.8
 Lrp10
low-density lipoprotein receptor-related protein 10
chr2_-_84715160 0.037 ENSMUST00000035840.5
 Zdhhc5
zinc finger, DHHC domain containing 5
chr1_-_175979114 0.030 ENSMUST00000104983.1
 B020018G12Rik
RIKEN cDNA B020018G12 gene
chr7_-_126897424 0.030 ENSMUST00000120007.1
 Tmem219
transmembrane protein 219
chr3_+_96629919 0.025 ENSMUST00000048915.6
 Rbm8a
RNA binding motif protein 8a
chr7_-_127208423 0.014 ENSMUST00000120705.1
 Tbc1d10b
TBC1 domain family, member 10b
chr3_-_86548268 0.005 ENSMUST00000077524.3
 Mab21l2
mab-21-like 2 (C. elegans)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:2000977 regulation of forebrain neuron differentiation(GO:2000977)
0.3 2.0 GO:0036233 glycine import(GO:0036233)
0.1 1.5 GO:0042572 retinol metabolic process(GO:0042572)
0.1 1.9 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 0.4 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.3 GO:0052695 cellular glucuronidation(GO:0052695)
0.0 0.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.3 GO:0048318 axial mesoderm development(GO:0048318)
0.0 0.7 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.7 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.1 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.4 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.1 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0000811 GINS complex(GO:0000811)
0.0 0.5 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.2 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 1.4 GO:0070469 respiratory chain(GO:0070469)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 1.5 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.2 1.3 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 1.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 1.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 1.5 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)