Motif ID: Hnf1a

Z-value: 0.907


Transcription factors associated with Hnf1a:

Gene SymbolEntrez IDGene Name
Hnf1a ENSMUSG00000029556.6 Hnf1a



Activity profile for motif Hnf1a.

activity profile for motif Hnf1a


Sorted Z-values histogram for motif Hnf1a

Sorted Z-values for motif Hnf1a



Network of associatons between targets according to the STRING database.


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_-_14598031 8.165 ENSMUST00000167776.2
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr19_-_14597983 8.142 ENSMUST00000052011.7
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr13_+_55152640 3.823 ENSMUST00000005452.5
 Fgfr4
fibroblast growth factor receptor 4
chr1_+_133309778 3.290 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
 Golt1a

Kiss1

GOLT1A
golgi transport 1 homolog A (S. cerevisiae)

KiSS-1 metastasis-suppressor

KISS1 isoform e
chr7_+_75610038 2.005 ENSMUST00000125771.1
 Akap13
A kinase (PRKA) anchor protein 13
chr13_-_53286052 1.890 ENSMUST00000021918.8
 Ror2
receptor tyrosine kinase-like orphan receptor 2
chrX_-_43167817 1.822 ENSMUST00000115058.1
ENSMUST00000115059.1
 Tenm1

teneurin transmembrane protein 1

chr14_-_70630149 1.773 ENSMUST00000022694.9
 Dmtn
dematin actin binding protein
chr9_+_99629496 1.748 ENSMUST00000131095.1
ENSMUST00000078367.5
ENSMUST00000112885.2
 Dzip1l


DAZ interacting protein 1-like


chr17_+_71204647 1.592 ENSMUST00000126681.1
 Lpin2
lipin 2
chr4_-_97778042 1.436 ENSMUST00000146447.1
 E130114P18Rik
RIKEN cDNA E130114P18 gene
chr4_+_150853919 1.203 ENSMUST00000073600.2
 Errfi1
ERBB receptor feedback inhibitor 1
chr9_+_99629823 1.176 ENSMUST00000112886.2
 Dzip1l
DAZ interacting protein 1-like
chr1_+_125676969 1.082 ENSMUST00000027581.6
 Gpr39
G protein-coupled receptor 39
chr12_+_5411641 1.032 ENSMUST00000163627.1
 2810032G03Rik
RIKEN cDNA 2810032G03 gene
chr7_+_141215852 1.015 ENSMUST00000046890.5
ENSMUST00000133763.1
 Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr7_-_119895446 0.964 ENSMUST00000098080.2
 Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr17_-_35132050 0.881 ENSMUST00000025249.6
 Apom
apolipoprotein M
chr7_+_141216626 0.858 ENSMUST00000141804.1
ENSMUST00000148975.1
 Rassf7

Ras association (RalGDS/AF-6) domain family (N-terminal) member 7

chr16_-_52296924 0.857 ENSMUST00000167115.1
 Alcam
activated leukocyte cell adhesion molecule
chr5_+_8046077 0.793 ENSMUST00000088786.4
 Sri
sorcin
chr2_-_68472138 0.767 ENSMUST00000102715.3
 Stk39
serine/threonine kinase 39
chr9_-_106158109 0.763 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
 Glyctk



glycerate kinase



chr9_+_57827284 0.725 ENSMUST00000163186.1
 Gm17231
predicted gene 17231
chr5_-_148995147 0.630 ENSMUST00000147473.1
 Katnal1
katanin p60 subunit A-like 1
chr12_+_76533540 0.542 ENSMUST00000075249.4
 Plekhg3
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr16_+_20651652 0.517 ENSMUST00000007212.8
 Psmd2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr5_+_24428208 0.460 ENSMUST00000115049.2
 Slc4a2
solute carrier family 4 (anion exchanger), member 2
chr14_-_36919314 0.383 ENSMUST00000182797.1
 Ccser2
coiled-coil serine rich 2
chr9_-_71163224 0.331 ENSMUST00000074465.2
 Aqp9
aquaporin 9
chr11_+_118428203 0.281 ENSMUST00000124861.1
 C1qtnf1
C1q and tumor necrosis factor related protein 1
chr14_-_36919513 0.275 ENSMUST00000182042.1
 Ccser2
coiled-coil serine rich 2
chr4_-_140617062 0.262 ENSMUST00000154979.1
 Arhgef10l
Rho guanine nucleotide exchange factor (GEF) 10-like
chr16_+_24448082 0.255 ENSMUST00000078988.2
 Lpp
LIM domain containing preferred translocation partner in lipoma
chr7_-_45062393 0.246 ENSMUST00000129101.1
 Prrg2
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr9_+_53771499 0.244 ENSMUST00000048670.8
 Slc35f2
solute carrier family 35, member F2
chr9_+_108795971 0.236 ENSMUST00000085018.4
 Ip6k2
inositol hexaphosphate kinase 2
chr19_+_6105774 0.212 ENSMUST00000044451.3
 Naaladl1
N-acetylated alpha-linked acidic dipeptidase-like 1
chr5_+_122391878 0.180 ENSMUST00000102525.4
 Arpc3
actin related protein 2/3 complex, subunit 3
chr2_+_110597298 0.177 ENSMUST00000045972.6
ENSMUST00000111026.2
 Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr2_-_86347764 0.174 ENSMUST00000099894.2
 Olfr1055
olfactory receptor 1055
chr7_-_144751968 0.152 ENSMUST00000155175.1
 Ano1
anoctamin 1, calcium activated chloride channel
chr11_+_78178105 0.091 ENSMUST00000147819.1
 Tlcd1
TLC domain containing 1
chr2_-_32424005 0.080 ENSMUST00000113307.2
 Slc25a25
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chr1_+_172698046 0.079 ENSMUST00000038495.3
 Crp
C-reactive protein, pentraxin-related
chr8_+_64947177 0.033 ENSMUST00000079896.7
ENSMUST00000026595.5
 Tmem192

transmembrane protein 192

chr5_-_114443993 0.019 ENSMUST00000112245.1
 Mmab
methylmalonic aciduria (cobalamin deficiency) type B homolog (human)
chr17_-_35046726 0.001 ENSMUST00000097338.4
 Msh5
mutS homolog 5 (E. coli)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 3.8 GO:0061144 alveolar secondary septum development(GO:0061144)
0.8 3.3 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.6 1.8 GO:1901731 calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731)
0.4 1.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.4 1.9 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.4 1.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.3 2.0 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.3 0.8 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.2 0.9 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)
0.1 0.8 GO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity(GO:0060315)
0.1 0.6 GO:0051013 microtubule severing(GO:0051013)
0.1 1.8 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 1.0 GO:0010225 response to UV-C(GO:0010225)
0.0 0.3 GO:0032782 urea transport(GO:0015840) bile acid secretion(GO:0032782) urea transmembrane transport(GO:0071918)
0.0 1.6 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.3 GO:2000857 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 14.4 GO:0016055 Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738)
0.0 0.9 GO:0008045 motor neuron axon guidance(GO:0008045)
0.0 0.1 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.2 GO:0006817 phosphate ion transport(GO:0006817)
0.0 0.7 GO:0001578 microtubule bundle formation(GO:0001578)
0.0 2.9 GO:0042384 cilium assembly(GO:0042384)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.3 0.8 GO:0042584 chromaffin granule membrane(GO:0042584)
0.2 0.9 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.9 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.5 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.0 2.9 GO:0005814 centriole(GO:0005814)
0.0 2.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 4.7 GO:0016324 apical plasma membrane(GO:0016324)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.4 3.8 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 17.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.2 3.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 2.0 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.1 1.9 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 0.2 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.6 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 0.3 GO:0015265 urea channel activity(GO:0015265)
0.0 1.0 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 1.8 GO:0043621 protein self-association(GO:0043621)
0.0 0.2 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.5 GO:0005452 inorganic anion exchanger activity(GO:0005452)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.2 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.9 GO:0016209 antioxidant activity(GO:0016209)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)