Motif ID: Hnf1b

Z-value: 0.823


Transcription factors associated with Hnf1b:

Gene SymbolEntrez IDGene Name
Hnf1b ENSMUSG00000020679.5 Hnf1b



Activity profile for motif Hnf1b.

activity profile for motif Hnf1b


Sorted Z-values histogram for motif Hnf1b

Sorted Z-values for motif Hnf1b



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf1b

PNG image of the network

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Top targets:


Showing 1 to 20 of 112 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_158814469 4.294 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr19_-_14598031 3.743 ENSMUST00000167776.2
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr19_-_14597983 3.700 ENSMUST00000052011.7
 Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr1_+_133309778 3.011 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
 Golt1a

Kiss1

GOLT1A
golgi transport 1 homolog A (S. cerevisiae)

KiSS-1 metastasis-suppressor

KISS1 isoform e
chr13_+_55152640 2.997 ENSMUST00000005452.5
 Fgfr4
fibroblast growth factor receptor 4
chr13_-_53286052 1.399 ENSMUST00000021918.8
 Ror2
receptor tyrosine kinase-like orphan receptor 2
chr7_-_119895446 1.312 ENSMUST00000098080.2
 Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr9_+_99629496 1.240 ENSMUST00000131095.1
ENSMUST00000078367.5
ENSMUST00000112885.2
 Dzip1l


DAZ interacting protein 1-like


chr1_+_133246092 1.188 ENSMUST00000038295.8
ENSMUST00000105082.2
 Plekha6

pleckstrin homology domain containing, family A member 6

chr9_+_99629823 1.098 ENSMUST00000112886.2
 Dzip1l
DAZ interacting protein 1-like
chr13_+_4191163 1.074 ENSMUST00000021634.2
 Akr1c13
aldo-keto reductase family 1, member C13
chr15_-_100425050 1.054 ENSMUST00000123461.1
 Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr19_-_57197496 1.043 ENSMUST00000111544.1
 Ablim1
actin-binding LIM protein 1
chr10_-_7212222 1.041 ENSMUST00000015346.5
 Cnksr3
Cnksr family member 3
chr12_-_12940600 1.006 ENSMUST00000130990.1
 Mycn
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr7_+_100537192 0.990 ENSMUST00000120454.1
 Coa4
cytochrome c oxidase assembly factor 4
chr12_+_5411641 0.881 ENSMUST00000163627.1
 2810032G03Rik
RIKEN cDNA 2810032G03 gene
chr4_+_150853919 0.865 ENSMUST00000073600.2
 Errfi1
ERBB receptor feedback inhibitor 1
chr6_-_102464667 0.837 ENSMUST00000032159.6
 Cntn3
contactin 3
chr19_-_57197556 0.827 ENSMUST00000099294.2
 Ablim1
actin-binding LIM protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.2 GO:0016055 Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738)
0.0 4.3 GO:0060349 bone morphogenesis(GO:0060349)
1.0 3.0 GO:0061144 alveolar secondary septum development(GO:0061144)
0.8 3.0 GO:0032275 luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278)
0.0 1.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.3 1.4 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.1 1.3 GO:0010225 response to UV-C(GO:0010225)
0.2 1.1 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 1.1 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.1 1.0 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 1.0 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.3 0.9 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.3 0.8 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.8 GO:1901524 regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.1 0.8 GO:0045607 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.2 0.7 GO:0032382 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373) positive regulation of cholesterol import(GO:1904109) positive regulation of sterol import(GO:2000911)
0.1 0.7 GO:0072757 cellular response to camptothecin(GO:0072757)
0.1 0.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.7 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.2 0.6 GO:0050748 negative regulation of lipoprotein metabolic process(GO:0050748)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.0 GO:0016324 apical plasma membrane(GO:0016324)
0.0 2.3 GO:0005814 centriole(GO:0005814)
0.0 1.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.2 1.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.7 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.7 GO:0030027 lamellipodium(GO:0030027)
0.2 0.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.0 0.6 GO:0010369 chromocenter(GO:0010369)
0.1 0.5 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.5 GO:0001741 XY body(GO:0001741)
0.1 0.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.4 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.3 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.3 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 4.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 3.0 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 3.0 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.4 GO:0017147 Wnt-protein binding(GO:0017147)
0.1 1.3 GO:0097602 cullin family protein binding(GO:0097602)
0.2 1.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.1 1.1 GO:0035380 C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.2 0.7 GO:0033814 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 0.7 GO:0070402 NADPH binding(GO:0070402)
0.1 0.5 GO:0000832 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.5 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.0 0.5 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.4 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.1 0.4 GO:0047696 beta-adrenergic receptor kinase activity(GO:0047696)
0.0 0.4 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.3 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)