Motif ID: Hnf1b
Z-value: 0.823
Transcription factors associated with Hnf1b:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hnf1b | ENSMUSG00000020679.5 | Hnf1b |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.0 | GO:0061144 | alveolar secondary septum development(GO:0061144) |
0.8 | 3.0 | GO:0032275 | luteinizing hormone secretion(GO:0032275) positive regulation of gonadotropin secretion(GO:0032278) |
0.3 | 0.9 | GO:0042536 | negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) |
0.3 | 1.4 | GO:0007223 | Wnt signaling pathway, calcium modulating pathway(GO:0007223) |
0.3 | 0.8 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) |
0.2 | 1.1 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.2 | 0.7 | GO:0032382 | positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373) positive regulation of cholesterol import(GO:1904109) positive regulation of sterol import(GO:2000911) |
0.2 | 0.5 | GO:1904884 | telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884) |
0.2 | 0.6 | GO:0050748 | negative regulation of lipoprotein metabolic process(GO:0050748) |
0.1 | 0.7 | GO:0072757 | cellular response to camptothecin(GO:0072757) |
0.1 | 0.8 | GO:1901524 | regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525) |
0.1 | 0.7 | GO:1900028 | negative regulation of ruffle assembly(GO:1900028) |
0.1 | 0.4 | GO:0044830 | modulation by host of viral RNA genome replication(GO:0044830) |
0.1 | 1.0 | GO:0097034 | mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034) |
0.1 | 1.3 | GO:0010225 | response to UV-C(GO:0010225) |
0.1 | 0.4 | GO:0034436 | glycoprotein transport(GO:0034436) |
0.1 | 0.5 | GO:0070072 | vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072) |
0.1 | 0.2 | GO:0021691 | cerebellar Purkinje cell layer maturation(GO:0021691) |
0.1 | 0.8 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
0.1 | 0.3 | GO:0044861 | protein transport into plasma membrane raft(GO:0044861) |
0.1 | 0.4 | GO:0007217 | tachykinin receptor signaling pathway(GO:0007217) |
0.1 | 0.5 | GO:0018095 | protein polyglutamylation(GO:0018095) |
0.0 | 0.7 | GO:0042178 | xenobiotic catabolic process(GO:0042178) |
0.0 | 0.3 | GO:0032782 | bile acid secretion(GO:0032782) |
0.0 | 1.1 | GO:0006805 | xenobiotic metabolic process(GO:0006805) |
0.0 | 0.1 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
0.0 | 0.2 | GO:2001012 | mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012) |
0.0 | 4.3 | GO:0060349 | bone morphogenesis(GO:0060349) |
0.0 | 0.3 | GO:0035095 | behavioral response to nicotine(GO:0035095) |
0.0 | 1.0 | GO:2000651 | positive regulation of sodium ion transmembrane transporter activity(GO:2000651) |
0.0 | 0.5 | GO:0006817 | phosphate ion transport(GO:0006817) |
0.0 | 0.2 | GO:0006659 | phosphatidylserine biosynthetic process(GO:0006659) |
0.0 | 0.2 | GO:2000857 | positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860) |
0.0 | 0.2 | GO:1903347 | negative regulation of bicellular tight junction assembly(GO:1903347) |
0.0 | 0.3 | GO:0061088 | sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) |
0.0 | 0.2 | GO:0006104 | succinyl-CoA metabolic process(GO:0006104) |
0.0 | 0.1 | GO:0015705 | iodide transport(GO:0015705) |
0.0 | 0.2 | GO:0042989 | sequestering of actin monomers(GO:0042989) |
0.0 | 0.1 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
0.0 | 0.4 | GO:0010718 | positive regulation of epithelial to mesenchymal transition(GO:0010718) |
0.0 | 1.9 | GO:0030032 | lamellipodium assembly(GO:0030032) |
0.0 | 0.2 | GO:0033147 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147) |
0.0 | 0.2 | GO:0015838 | amino-acid betaine transport(GO:0015838) |
0.0 | 0.1 | GO:0052695 | cellular glucuronidation(GO:0052695) |
0.0 | 0.4 | GO:0072698 | protein localization to microtubule cytoskeleton(GO:0072698) |
0.0 | 7.2 | GO:0016055 | Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738) |
0.0 | 0.0 | GO:0060737 | prostate epithelial cord elongation(GO:0060523) prostate gland morphogenetic growth(GO:0060737) |
0.0 | 0.1 | GO:0035428 | hexose transmembrane transport(GO:0035428) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 1.1 | GO:0070826 | paraferritin complex(GO:0070826) |
0.2 | 0.6 | GO:0034365 | discoidal high-density lipoprotein particle(GO:0034365) |
0.1 | 0.7 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.1 | 0.4 | GO:0034361 | very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385) |
0.1 | 0.5 | GO:0000220 | vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220) |
0.1 | 0.3 | GO:0061689 | tricellular tight junction(GO:0061689) |
0.0 | 0.2 | GO:0030062 | mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062) |
0.0 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
0.0 | 0.4 | GO:0097431 | mitotic spindle pole(GO:0097431) |
0.0 | 0.3 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
0.0 | 0.3 | GO:0044352 | pinosome(GO:0044352) macropinosome(GO:0044354) |
0.0 | 0.6 | GO:0010369 | chromocenter(GO:0010369) |
0.0 | 2.3 | GO:0005814 | centriole(GO:0005814) |
0.0 | 0.5 | GO:0001741 | XY body(GO:0001741) |
0.0 | 0.3 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
0.0 | 1.7 | GO:0001725 | stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517) |
0.0 | 0.7 | GO:0030027 | lamellipodium(GO:0030027) |
0.0 | 0.2 | GO:0030126 | COPI vesicle coat(GO:0030126) |
0.0 | 0.2 | GO:0035631 | CD40 receptor complex(GO:0035631) |
0.0 | 0.9 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
0.0 | 0.1 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.0 | 0.2 | GO:0033655 | host cell cytoplasm(GO:0030430) host intracellular part(GO:0033646) host cell cytoplasm part(GO:0033655) intracellular region of host(GO:0043656) |
0.0 | 3.0 | GO:0016324 | apical plasma membrane(GO:0016324) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 3.0 | GO:0005007 | fibroblast growth factor-activated receptor activity(GO:0005007) |
0.2 | 1.1 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.2 | 0.7 | GO:0033814 | propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121) |
0.2 | 3.0 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
0.1 | 0.4 | GO:0034437 | glycoprotein transporter activity(GO:0034437) |
0.1 | 0.5 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
0.1 | 7.6 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
0.1 | 0.5 | GO:0032405 | MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407) |
0.1 | 0.2 | GO:0001226 | RNA polymerase II transcription corepressor binding(GO:0001226) |
0.1 | 0.4 | GO:0047696 | beta-adrenergic receptor kinase activity(GO:0047696) |
0.1 | 1.3 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.1 | 0.2 | GO:0005128 | erythropoietin receptor binding(GO:0005128) |
0.1 | 0.7 | GO:0005522 | profilin binding(GO:0005522) |
0.1 | 0.2 | GO:0008384 | IkappaB kinase activity(GO:0008384) |
0.1 | 1.1 | GO:0035380 | C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677) |
0.0 | 0.3 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.0 | 4.3 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.0 | 1.4 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.0 | 0.5 | GO:0008553 | hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553) |
0.0 | 0.7 | GO:0070402 | NADPH binding(GO:0070402) |
0.0 | 0.2 | GO:0015265 | urea channel activity(GO:0015265) |
0.0 | 0.1 | GO:0016668 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) |
0.0 | 0.3 | GO:0004889 | acetylcholine-activated cation-selective channel activity(GO:0004889) |
0.0 | 0.4 | GO:0042165 | neurotransmitter binding(GO:0042165) |
0.0 | 0.1 | GO:0015111 | iodide transmembrane transporter activity(GO:0015111) |
0.0 | 0.1 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
0.0 | 0.2 | GO:0004774 | succinate-CoA ligase activity(GO:0004774) |
0.0 | 0.3 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
0.0 | 0.2 | GO:0005328 | neurotransmitter:sodium symporter activity(GO:0005328) |
0.0 | 0.2 | GO:0005537 | mannose binding(GO:0005537) |