Motif ID: Hoxa11_Hoxc12

Z-value: 0.951

Transcription factors associated with Hoxa11_Hoxc12:

Gene SymbolEntrez IDGene Name
Hoxa11 ENSMUSG00000038210.9 Hoxa11
Hoxc12 ENSMUSG00000050328.2 Hoxc12



Activity profile for motif Hoxa11_Hoxc12.

activity profile for motif Hoxa11_Hoxc12


Sorted Z-values histogram for motif Hoxa11_Hoxc12

Sorted Z-values for motif Hoxa11_Hoxc12



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa11_Hoxc12

PNG image of the network

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Top targets:


Showing 1 to 20 of 123 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_178529113 4.182 ENSMUST00000161017.1
 Kif26b
kinesin family member 26B
chr6_+_108213086 1.212 ENSMUST00000032192.6
 Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr13_+_65512678 1.155 ENSMUST00000081471.2
 Gm10139
predicted gene 10139
chr18_+_69346143 1.102 ENSMUST00000114980.1
 Tcf4
transcription factor 4
chr18_-_15063560 1.063 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chr10_-_67912620 0.983 ENSMUST00000064656.7
 Zfp365
zinc finger protein 365
chr3_-_117360876 0.969 ENSMUST00000061071.8
 D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr11_-_62457772 0.921 ENSMUST00000127471.2
 Ncor1
nuclear receptor co-repressor 1
chr5_-_20951769 0.872 ENSMUST00000036489.5
 Rsbn1l
round spermatid basic protein 1-like
chr5_+_32611171 0.843 ENSMUST00000072311.6
ENSMUST00000168707.2
 Yes1

Yamaguchi sarcoma viral (v-yes) oncogene homolog 1

chr11_-_30986326 0.828 ENSMUST00000020553.4
ENSMUST00000101394.4
 Chac2

ChaC, cation transport regulator 2

chr8_+_40307458 0.772 ENSMUST00000068999.7
 Micu3
mitochondrial calcium uptake family, member 3
chr11_+_82045705 0.740 ENSMUST00000021011.2
 Ccl7
chemokine (C-C motif) ligand 7
chr5_+_66968961 0.676 ENSMUST00000132991.1
 Limch1
LIM and calponin homology domains 1
chr17_-_6477102 0.648 ENSMUST00000167717.2
 Tmem181b-ps
transmembrane protein 181B, pseudogene
chr9_+_53771499 0.639 ENSMUST00000048670.8
 Slc35f2
solute carrier family 35, member F2
chr13_+_16014457 0.610 ENSMUST00000164993.1
 Inhba
inhibin beta-A
chr5_-_123666682 0.607 ENSMUST00000149410.1
 Clip1
CAP-GLY domain containing linker protein 1
chr17_+_6270475 0.569 ENSMUST00000088940.4
 Tmem181a
transmembrane protein 181A
chr2_+_23068168 0.544 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
 Acbd5


acyl-Coenzyme A binding domain containing 5



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 4.2 GO:0072092 ureteric bud invasion(GO:0072092)
0.2 1.2 GO:0042045 epithelial fluid transport(GO:0042045)
0.1 1.1 GO:0042118 endothelial cell activation(GO:0042118)
0.3 1.0 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.2 0.9 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 0.8 GO:0031999 negative regulation of fatty acid beta-oxidation(GO:0031999)
0.1 0.8 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 0.7 GO:0071361 cellular response to ethanol(GO:0071361)
0.2 0.6 GO:0009405 pathogenesis(GO:0009405)
0.2 0.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 0.6 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 0.5 GO:0030242 pexophagy(GO:0030242)
0.0 0.5 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.5 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.1 0.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.4 GO:0060056 mammary gland involution(GO:0060056)
0.0 0.4 GO:0043030 regulation of macrophage activation(GO:0043030)
0.1 0.3 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.0 0.3 GO:0070314 G1 to G0 transition(GO:0070314)
0.0 0.3 GO:0097320 membrane tubulation(GO:0097320)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.2 GO:0005871 kinesin complex(GO:0005871)
0.4 1.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 1.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.2 0.6 GO:0043512 inhibin A complex(GO:0043512)
0.1 0.6 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.2 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.4 1.2 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.3 1.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.9 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.8 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.6 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.4 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.3 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.3 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.3 GO:0001727 lipid kinase activity(GO:0001727)
0.1 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0098821 BMP receptor activity(GO:0098821)
0.0 0.2 GO:0070728 leucine binding(GO:0070728)
0.0 0.2 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.2 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934)
0.0 0.2 GO:0008046 axon guidance receptor activity(GO:0008046)