Motif ID: Hoxa2

Z-value: 0.607


Transcription factors associated with Hoxa2:

Gene SymbolEntrez IDGene Name
Hoxa2 ENSMUSG00000014704.8 Hoxa2



Activity profile for motif Hoxa2.

activity profile for motif Hoxa2


Sorted Z-values histogram for motif Hoxa2

Sorted Z-values for motif Hoxa2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_65873478 1.766 ENSMUST00000025395.8
ENSMUST00000173530.1
 Grp

gastrin releasing peptide

chrY_+_90755657 1.648 ENSMUST00000167967.2
 Gm21857
predicted gene, 21857
chrX_-_103483205 1.004 ENSMUST00000127786.2
 Xist
inactive X specific transcripts
chr1_+_178798438 0.566 ENSMUST00000160789.1
 Kif26b
kinesin family member 26B
chr2_-_84775420 0.550 ENSMUST00000111641.1
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr16_-_23890805 0.521 ENSMUST00000004480.3
 Sst
somatostatin
chr12_-_103443653 0.491 ENSMUST00000055071.8
 Ifi27l2a
interferon, alpha-inducible protein 27 like 2A
chr17_+_78508063 0.489 ENSMUST00000024880.9
 Vit
vitrin
chr2_-_84775388 0.477 ENSMUST00000023994.3
 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr11_-_58801944 0.454 ENSMUST00000094156.4
ENSMUST00000060581.3
 Fam183b

family with sequence similarity 183, member B

chrX_+_110814390 0.421 ENSMUST00000078229.3
 Pou3f4
POU domain, class 3, transcription factor 4
chr9_+_51621425 0.415 ENSMUST00000089534.4
 Gm7293
predicted gene 7293
chr10_+_57784914 0.408 ENSMUST00000165013.1
 Fabp7
fatty acid binding protein 7, brain
chr14_+_51091077 0.387 ENSMUST00000022428.5
ENSMUST00000171688.1
 Rnase4
Ang
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr10_-_58675631 0.379 ENSMUST00000003312.4
 Edar
ectodysplasin-A receptor
chr3_+_62419668 0.376 ENSMUST00000161057.1
 Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chrX_+_73192222 0.372 ENSMUST00000101486.4
 Xlr3b
X-linked lymphocyte-regulated 3B
chr4_-_147936713 0.368 ENSMUST00000105712.1
ENSMUST00000019199.7
 Plod1

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

chr2_-_5063996 0.366 ENSMUST00000114996.1
 Optn
optineurin
chr4_+_145510759 0.366 ENSMUST00000105742.1
ENSMUST00000136309.1
 Gm13225

predicted gene 13225


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 81 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.3 1.0 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.3 1.0 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.8 GO:0060134 prepulse inhibition(GO:0060134)
0.2 0.6 GO:2000562 negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.2 0.6 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.6 GO:0048245 eosinophil chemotaxis(GO:0048245)
0.1 0.5 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.5 GO:0045672 positive regulation of osteoclast differentiation(GO:0045672)
0.1 0.4 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.1 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.4 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.0 0.4 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.4 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.4 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.4 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.4 GO:0006940 regulation of smooth muscle contraction(GO:0006940)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.3 GO:0000805 X chromosome(GO:0000805)
0.0 0.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 0.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 0.2 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.1 0.2 GO:0005584 collagen type I trimer(GO:0005584)
0.1 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.2 GO:0033093 multivesicular body membrane(GO:0032585) Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.1 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.0 0.1 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.1 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.1 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0034366 spherical high-density lipoprotein particle(GO:0034366) neurofibrillary tangle(GO:0097418)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.1 1.0 GO:0001848 complement binding(GO:0001848)
0.1 0.6 GO:0016936 galactoside binding(GO:0016936)
0.0 0.6 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.5 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0005179 hormone activity(GO:0005179)
0.1 0.4 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.4 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.3 GO:0019863 IgE binding(GO:0019863)
0.1 0.3 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.3 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.3 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.3 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.3 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)