Motif ID: Hoxa5

Z-value: 0.755


Transcription factors associated with Hoxa5:

Gene SymbolEntrez IDGene Name
Hoxa5 ENSMUSG00000038253.6 Hoxa5



Activity profile for motif Hoxa5.

activity profile for motif Hoxa5


Sorted Z-values histogram for motif Hoxa5

Sorted Z-values for motif Hoxa5



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_17574268 2.038 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr9_+_94669876 1.581 ENSMUST00000033463.9
 Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr5_+_17574726 1.496 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr6_-_60829826 1.083 ENSMUST00000163779.1
 Snca
synuclein, alpha
chr13_-_92030897 1.067 ENSMUST00000149630.1
 Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chrY_+_90755657 1.051 ENSMUST00000167967.2
 Gm21857
predicted gene, 21857
chr13_-_92131494 1.025 ENSMUST00000099326.3
ENSMUST00000146492.1
 Rasgrf2

RAS protein-specific guanine nucleotide-releasing factor 2

chr16_+_43508118 0.974 ENSMUST00000114690.1
 Zbtb20
zinc finger and BTB domain containing 20
chrY_+_1010543 0.956 ENSMUST00000091197.3
 Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr2_-_72986716 0.917 ENSMUST00000112062.1
 Gm11084
predicted gene 11084
chr12_+_77238093 0.914 ENSMUST00000177595.1
ENSMUST00000171770.2
 Fut8

fucosyltransferase 8

chr1_+_104768510 0.873 ENSMUST00000062528.8
 Cdh20
cadherin 20
chr6_+_17463749 0.795 ENSMUST00000115443.1
 Met
met proto-oncogene
chr11_-_83649349 0.775 ENSMUST00000001008.5
 Ccl3
chemokine (C-C motif) ligand 3
chr11_+_16752203 0.751 ENSMUST00000102884.3
ENSMUST00000020329.6
 Egfr

epidermal growth factor receptor

chrY_-_1286563 0.749 ENSMUST00000091190.5
 Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr16_+_43247278 0.733 ENSMUST00000114691.1
ENSMUST00000079441.6
 Zbtb20

zinc finger and BTB domain containing 20

chr7_-_83550258 0.732 ENSMUST00000177929.1
 Gm10610
predicted gene 10610
chr8_+_57455898 0.723 ENSMUST00000034023.3
 Scrg1
scrapie responsive gene 1
chr3_+_62419668 0.704 ENSMUST00000161057.1
 Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 109 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.5 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 2.1 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 2.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 1.6 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.3 1.1 GO:0010040 response to iron(II) ion(GO:0010040) positive regulation of hydrogen peroxide metabolic process(GO:0010726) negative regulation of synaptic transmission, dopaminergic(GO:0032227) negative regulation of catecholamine metabolic process(GO:0045914) negative regulation of dopamine metabolic process(GO:0045963) cellular response to copper ion(GO:0071280) regulation of peroxidase activity(GO:2000468)
0.0 1.1 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 1.0 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.3 0.9 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.2 0.8 GO:0038145 macrophage colony-stimulating factor signaling pathway(GO:0038145)
0.2 0.8 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.1 0.8 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.8 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.7 GO:1902969 mitotic DNA replication(GO:1902969)
0.1 0.7 GO:0019532 oxalate transport(GO:0019532)
0.0 0.7 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.7 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.7 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.2 0.6 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.2 0.6 GO:0043181 vacuolar sequestering(GO:0043181)
0.0 0.6 GO:0009409 response to cold(GO:0009409)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 54 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.5 GO:0055037 recycling endosome(GO:0055037)
0.3 1.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.9 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.9 GO:0009925 basal plasma membrane(GO:0009925)
0.3 0.8 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.3 0.8 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.7 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.6 GO:0043083 synaptic cleft(GO:0043083)
0.2 0.5 GO:0000811 GINS complex(GO:0000811)
0.0 0.5 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.5 GO:0030057 desmosome(GO:0030057)
0.1 0.4 GO:0002177 manchette(GO:0002177)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.1 0.3 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.3 GO:0061574 ASAP complex(GO:0061574)
0.0 0.3 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.3 GO:0002080 acrosomal membrane(GO:0002080)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 76 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 3.5 GO:0038191 neuropilin binding(GO:0038191)
0.0 2.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 1.6 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 1.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 1.1 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 1.0 GO:0008009 chemokine activity(GO:0008009)
0.3 0.8 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.8 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.1 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.7 GO:0042287 MHC protein binding(GO:0042287)
0.2 0.6 GO:0032450 oligo-1,6-glucosidase activity(GO:0004574) maltose alpha-glucosidase activity(GO:0032450)
0.2 0.6 GO:0098809 nitrite reductase activity(GO:0098809)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.5 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.5 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.4 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.4 GO:0032183 SUMO binding(GO:0032183)