Motif ID: Hoxa6

Z-value: 1.286


Transcription factors associated with Hoxa6:

Gene SymbolEntrez IDGene Name
Hoxa6 ENSMUSG00000043219.8 Hoxa6



Activity profile for motif Hoxa6.

activity profile for motif Hoxa6


Sorted Z-values histogram for motif Hoxa6

Sorted Z-values for motif Hoxa6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa6

PNG image of the network

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Top targets:


Showing 1 to 20 of 196 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_71528657 13.245 ENSMUST00000126400.1
 Dlx1
distal-less homeobox 1
chr16_+_42907563 8.909 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr19_-_59170978 6.145 ENSMUST00000172821.2
 Vax1
ventral anterior homeobox containing gene 1
chr8_-_46294592 5.885 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr1_+_19103022 5.492 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr5_-_123141067 4.936 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
 AI480526


expressed sequence AI480526


chr14_-_48665098 3.928 ENSMUST00000118578.1
 Otx2
orthodenticle homolog 2 (Drosophila)
chr2_+_70474923 3.825 ENSMUST00000100043.2
 Sp5
trans-acting transcription factor 5
chr12_+_38783503 3.487 ENSMUST00000159334.1
 Etv1
ets variant gene 1
chr13_-_103764502 3.378 ENSMUST00000074616.5
 Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr12_+_38783455 3.307 ENSMUST00000161980.1
ENSMUST00000160701.1
 Etv1

ets variant gene 1

chr18_-_84086379 3.261 ENSMUST00000060303.8
 Tshz1
teashirt zinc finger family member 1
chr13_+_63014934 3.236 ENSMUST00000091560.4
 2010111I01Rik
RIKEN cDNA 2010111I01 gene
chr1_-_163313661 3.233 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
 Prrx1


paired related homeobox 1


chr7_-_109170308 3.007 ENSMUST00000036992.7
 Lmo1
LIM domain only 1
chr3_+_118430299 2.915 ENSMUST00000180774.1
 Gm26871
predicted gene, 26871
chr19_+_55894508 2.803 ENSMUST00000142291.1
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr13_-_84064772 2.668 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr1_-_165934900 2.519 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
 Pou2f1


POU domain, class 2, transcription factor 1


chr12_-_34528844 2.392 ENSMUST00000110819.2
 Hdac9
histone deacetylase 9

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 14.0 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
4.4 13.2 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
1.8 7.0 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.2 6.4 GO:0030901 midbrain development(GO:0030901)
0.9 6.1 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.2 6.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.2 5.9 GO:0010259 multicellular organism aging(GO:0010259)
0.1 4.7 GO:0022900 electron transport chain(GO:0022900)
0.9 4.5 GO:0061047 positive regulation of branching involved in lung morphogenesis(GO:0061047)
0.2 4.3 GO:0035855 megakaryocyte development(GO:0035855)
1.0 3.9 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.2 3.8 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.5 3.5 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
1.1 3.3 GO:0060023 soft palate development(GO:0060023)
0.5 3.2 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.4 3.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 3.2 GO:0042474 middle ear morphogenesis(GO:0042474)
0.1 3.2 GO:0043171 peptide catabolic process(GO:0043171)
0.0 2.6 GO:0007605 sensory perception of sound(GO:0007605)
0.4 2.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 14.9 GO:0005667 transcription factor complex(GO:0005667)
0.0 7.6 GO:0030426 growth cone(GO:0030426)
0.6 5.7 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 4.1 GO:0070469 respiratory chain(GO:0070469)
0.0 3.6 GO:0031012 extracellular matrix(GO:0031012)
0.0 3.4 GO:0005681 spliceosomal complex(GO:0005681)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.2 2.2 GO:0030478 actin cap(GO:0030478)
0.0 1.9 GO:0045171 intercellular bridge(GO:0045171)
0.4 1.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.3 GO:0098644 complex of collagen trimers(GO:0098644)
0.3 1.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.2 1.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 1.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.0 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.8 GO:0071439 clathrin complex(GO:0071439)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.7 GO:0043205 fibril(GO:0043205)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 19.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 17.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 14.9 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.8 6.1 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.0 5.9 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.2 5.0 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 3.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.5 3.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 3.2 GO:0071837 HMG box domain binding(GO:0071837)
0.2 3.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 3.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.1 2.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 2.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.3 2.3 GO:0039706 co-receptor binding(GO:0039706)
0.1 2.3 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.3 2.1 GO:1990188 euchromatin binding(GO:1990188)
0.3 2.0 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.2 1.9 GO:0038191 neuropilin binding(GO:0038191)
0.0 1.9 GO:0000976 transcription regulatory region sequence-specific DNA binding(GO:0000976)
0.1 1.8 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)