Motif ID: Hoxa6
Z-value: 1.286
Transcription factors associated with Hoxa6:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxa6 | ENSMUSG00000043219.8 | Hoxa6 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.4 | 13.2 | GO:0021893 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) |
1.8 | 7.0 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
1.1 | 3.3 | GO:0060023 | soft palate development(GO:0060023) |
1.0 | 3.9 | GO:0046013 | regulation of T cell homeostatic proliferation(GO:0046013) |
0.9 | 4.5 | GO:0061047 | positive regulation of branching involved in lung morphogenesis(GO:0061047) |
0.9 | 6.1 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
0.7 | 2.0 | GO:1904139 | microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139) |
0.5 | 3.5 | GO:0010908 | regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730) |
0.5 | 1.9 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) negative regulation of type B pancreatic cell apoptotic process(GO:2000675) |
0.5 | 3.2 | GO:0071699 | olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699) |
0.4 | 2.4 | GO:0060385 | axonogenesis involved in innervation(GO:0060385) |
0.4 | 3.2 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
0.4 | 1.2 | GO:1990314 | cellular response to insulin-like growth factor stimulus(GO:1990314) |
0.4 | 14.0 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
0.4 | 1.5 | GO:1903378 | positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378) |
0.3 | 1.6 | GO:0003199 | endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504) |
0.2 | 0.7 | GO:2001015 | G1 to G0 transition involved in cell differentiation(GO:0070315) negative regulation of skeletal muscle cell differentiation(GO:2001015) |
0.2 | 1.2 | GO:0051365 | cellular response to potassium ion starvation(GO:0051365) |
0.2 | 2.4 | GO:0034983 | peptidyl-lysine deacetylation(GO:0034983) regulation of skeletal muscle fiber development(GO:0048742) |
0.2 | 0.7 | GO:0090327 | negative regulation of locomotion involved in locomotory behavior(GO:0090327) |
0.2 | 1.8 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
0.2 | 0.6 | GO:0097274 | urea homeostasis(GO:0097274) |
0.2 | 1.2 | GO:0032229 | positive regulation of gamma-aminobutyric acid secretion(GO:0014054) negative regulation of synaptic transmission, GABAergic(GO:0032229) |
0.2 | 1.3 | GO:1900747 | negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747) |
0.2 | 6.1 | GO:0007638 | mechanosensory behavior(GO:0007638) |
0.2 | 0.4 | GO:0090245 | axis elongation involved in somitogenesis(GO:0090245) |
0.2 | 4.3 | GO:0035855 | megakaryocyte development(GO:0035855) |
0.2 | 2.1 | GO:0021780 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
0.2 | 0.3 | GO:0021562 | vestibulocochlear nerve development(GO:0021562) |
0.2 | 1.2 | GO:0045200 | establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) |
0.2 | 1.0 | GO:0006570 | tyrosine metabolic process(GO:0006570) |
0.2 | 1.0 | GO:0060539 | diaphragm development(GO:0060539) |
0.2 | 3.8 | GO:0036342 | post-anal tail morphogenesis(GO:0036342) |
0.2 | 5.9 | GO:0010259 | multicellular organism aging(GO:0010259) |
0.2 | 6.4 | GO:0030901 | midbrain development(GO:0030901) |
0.1 | 2.3 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
0.1 | 1.3 | GO:0021979 | hypothalamus cell differentiation(GO:0021979) |
0.1 | 3.2 | GO:0042474 | middle ear morphogenesis(GO:0042474) |
0.1 | 1.5 | GO:0021800 | cerebral cortex tangential migration(GO:0021800) |
0.1 | 3.2 | GO:0043171 | peptide catabolic process(GO:0043171) |
0.1 | 0.7 | GO:0032049 | cardiolipin biosynthetic process(GO:0032049) |
0.1 | 0.3 | GO:0015712 | hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760) phosphate ion transmembrane transport(GO:0035435) |
0.1 | 0.5 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
0.1 | 0.2 | GO:0061303 | oculomotor nerve development(GO:0021557) cornea development in camera-type eye(GO:0061303) |
0.1 | 0.8 | GO:0002118 | aggressive behavior(GO:0002118) |
0.1 | 4.7 | GO:0022900 | electron transport chain(GO:0022900) |
0.1 | 1.8 | GO:0010107 | potassium ion import(GO:0010107) |
0.1 | 0.3 | GO:0010835 | regulation of protein ADP-ribosylation(GO:0010835) |
0.1 | 0.6 | GO:0042118 | endothelial cell activation(GO:0042118) |
0.1 | 0.8 | GO:0051764 | actin crosslink formation(GO:0051764) |
0.1 | 1.4 | GO:0048665 | neuron fate specification(GO:0048665) |
0.1 | 1.0 | GO:0033194 | response to hydroperoxide(GO:0033194) |
0.1 | 0.3 | GO:0060040 | retinal bipolar neuron differentiation(GO:0060040) |
0.0 | 0.3 | GO:0006686 | sphingomyelin biosynthetic process(GO:0006686) |
0.0 | 0.7 | GO:0009048 | dosage compensation by inactivation of X chromosome(GO:0009048) |
0.0 | 0.2 | GO:0034196 | acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197) |
0.0 | 1.2 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
0.0 | 1.3 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
0.0 | 0.1 | GO:0003150 | muscular septum morphogenesis(GO:0003150) |
0.0 | 2.2 | GO:0006940 | regulation of smooth muscle contraction(GO:0006940) |
0.0 | 0.9 | GO:0006625 | protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663) |
0.0 | 0.2 | GO:0009249 | protein lipoylation(GO:0009249) |
0.0 | 2.0 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.6 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
0.0 | 0.3 | GO:0021684 | cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707) |
0.0 | 2.6 | GO:0007605 | sensory perception of sound(GO:0007605) |
0.0 | 0.3 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
0.0 | 0.8 | GO:0034605 | cellular response to heat(GO:0034605) |
0.0 | 0.8 | GO:1900087 | positive regulation of G1/S transition of mitotic cell cycle(GO:1900087) |
0.0 | 0.2 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
0.0 | 0.4 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
0.0 | 0.4 | GO:0007617 | mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705) |
0.0 | 1.0 | GO:0009060 | aerobic respiration(GO:0009060) |
0.0 | 0.3 | GO:0001833 | inner cell mass cell proliferation(GO:0001833) |
0.0 | 1.8 | GO:0021987 | cerebral cortex development(GO:0021987) |
0.0 | 0.8 | GO:0007566 | embryo implantation(GO:0007566) |
0.0 | 0.3 | GO:0009954 | proximal/distal pattern formation(GO:0009954) |
0.0 | 0.6 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
0.0 | 0.2 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
0.0 | 0.4 | GO:0090162 | establishment of epithelial cell polarity(GO:0090162) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 5.7 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
0.4 | 1.5 | GO:1990452 | Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452) |
0.3 | 1.2 | GO:0036454 | insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567) |
0.2 | 2.2 | GO:0030478 | actin cap(GO:0030478) |
0.2 | 1.2 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
0.1 | 1.0 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
0.1 | 0.4 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
0.1 | 0.7 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
0.1 | 1.2 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
0.1 | 0.3 | GO:0031230 | intrinsic component of cell outer membrane(GO:0031230) integral component of cell outer membrane(GO:0045203) |
0.1 | 0.8 | GO:0071439 | clathrin complex(GO:0071439) |
0.1 | 0.2 | GO:0044299 | C-fiber(GO:0044299) |
0.1 | 0.5 | GO:0005796 | Golgi lumen(GO:0005796) |
0.1 | 0.2 | GO:0000172 | ribonuclease MRP complex(GO:0000172) |
0.1 | 1.3 | GO:0098644 | complex of collagen trimers(GO:0098644) |
0.1 | 4.1 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.7 | GO:0043205 | fibril(GO:0043205) |
0.0 | 0.6 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.0 | 1.0 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
0.0 | 1.9 | GO:0045171 | intercellular bridge(GO:0045171) |
0.0 | 14.9 | GO:0005667 | transcription factor complex(GO:0005667) |
0.0 | 7.6 | GO:0030426 | growth cone(GO:0030426) |
0.0 | 2.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.5 | GO:0005581 | collagen trimer(GO:0005581) |
0.0 | 0.6 | GO:0016363 | nuclear matrix(GO:0016363) |
0.0 | 0.2 | GO:0031528 | microvillus membrane(GO:0031528) |
0.0 | 0.4 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.0 | 0.3 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.0 | 1.1 | GO:0009925 | basal plasma membrane(GO:0009925) |
0.0 | 3.4 | GO:0005681 | spliceosomal complex(GO:0005681) |
0.0 | 3.6 | GO:0031012 | extracellular matrix(GO:0031012) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 6.1 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
0.5 | 3.2 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
0.3 | 3.2 | GO:0071837 | HMG box domain binding(GO:0071837) |
0.3 | 2.1 | GO:1990188 | euchromatin binding(GO:1990188) |
0.3 | 1.5 | GO:0050816 | phosphothreonine binding(GO:0050816) |
0.3 | 2.0 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
0.3 | 2.3 | GO:0039706 | co-receptor binding(GO:0039706) |
0.2 | 5.0 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
0.2 | 3.0 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
0.2 | 1.2 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.2 | 3.2 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
0.2 | 1.9 | GO:0038191 | neuropilin binding(GO:0038191) |
0.2 | 0.8 | GO:0005134 | interleukin-2 receptor binding(GO:0005134) |
0.2 | 0.6 | GO:0001011 | transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087) |
0.1 | 3.5 | GO:0045295 | gamma-catenin binding(GO:0045295) |
0.1 | 0.7 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
0.1 | 19.4 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
0.1 | 0.7 | GO:0008808 | cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) |
0.1 | 2.3 | GO:0005242 | inward rectifier potassium channel activity(GO:0005242) |
0.1 | 2.4 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
0.1 | 0.4 | GO:0050436 | microfibril binding(GO:0050436) |
0.1 | 0.7 | GO:0031432 | titin binding(GO:0031432) |
0.1 | 0.3 | GO:0033188 | sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493) |
0.1 | 0.8 | GO:0004865 | protein serine/threonine phosphatase inhibitor activity(GO:0004865) |
0.1 | 2.6 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
0.1 | 1.0 | GO:0016863 | intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863) |
0.1 | 0.2 | GO:0000171 | ribonuclease MRP activity(GO:0000171) |
0.1 | 17.1 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
0.1 | 0.6 | GO:0008568 | microtubule-severing ATPase activity(GO:0008568) |
0.1 | 1.8 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 1.2 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
0.1 | 1.5 | GO:0005112 | Notch binding(GO:0005112) |
0.0 | 14.9 | GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977) |
0.0 | 0.3 | GO:0015114 | phosphate ion transmembrane transporter activity(GO:0015114) |
0.0 | 1.5 | GO:0048487 | beta-tubulin binding(GO:0048487) |
0.0 | 1.3 | GO:0050840 | extracellular matrix binding(GO:0050840) |
0.0 | 0.8 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.0 | 0.2 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.0 | 1.2 | GO:0042054 | histone methyltransferase activity(GO:0042054) |
0.0 | 0.5 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
0.0 | 1.9 | GO:0000976 | transcription regulatory region sequence-specific DNA binding(GO:0000976) |
0.0 | 0.0 | GO:0001224 | RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription corepressor binding(GO:0001226) |
0.0 | 5.9 | GO:0043565 | sequence-specific DNA binding(GO:0043565) |
0.0 | 1.2 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
0.0 | 0.6 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.9 | GO:0031593 | polyubiquitin binding(GO:0031593) |
0.0 | 0.6 | GO:0001540 | beta-amyloid binding(GO:0001540) |
0.0 | 0.1 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.0 | 0.7 | GO:0003743 | translation initiation factor activity(GO:0003743) |
0.0 | 0.2 | GO:1905030 | voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030) |