Motif ID: Hoxa7_Hoxc8

Z-value: 0.378

Transcription factors associated with Hoxa7_Hoxc8:

Gene SymbolEntrez IDGene Name
Hoxa7 ENSMUSG00000038236.6 Hoxa7
Hoxc8 ENSMUSG00000001657.6 Hoxc8



Activity profile for motif Hoxa7_Hoxc8.

activity profile for motif Hoxa7_Hoxc8


Sorted Z-values histogram for motif Hoxa7_Hoxc8

Sorted Z-values for motif Hoxa7_Hoxc8



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa7_Hoxc8

PNG image of the network

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Top targets:


Showing 1 to 20 of 86 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_143933089 1.173 ENSMUST00000087313.3
 Dcx
doublecortin
chr15_-_67113909 1.073 ENSMUST00000092640.5
 St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr12_-_55014329 0.596 ENSMUST00000172875.1
 Baz1a
bromodomain adjacent to zinc finger domain 1A
chr9_-_90255927 0.542 ENSMUST00000144646.1
 Tbc1d2b
TBC1 domain family, member 2B
chr14_-_100149764 0.532 ENSMUST00000097079.4
 Klf12
Kruppel-like factor 12
chr18_+_86711059 0.516 ENSMUST00000068423.3
 Cbln2
cerebellin 2 precursor protein
chr2_+_69897255 0.510 ENSMUST00000131553.1
 Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr4_+_102589687 0.478 ENSMUST00000097949.4
ENSMUST00000106901.1
 Pde4b

phosphodiesterase 4B, cAMP specific

chrX_-_143933204 0.470 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chr3_+_55782500 0.460 ENSMUST00000075422.4
 Mab21l1
mab-21-like 1 (C. elegans)
chr1_+_72284367 0.456 ENSMUST00000027380.5
ENSMUST00000141783.1
 Tmem169

transmembrane protein 169

chr15_-_37458523 0.446 ENSMUST00000116445.2
 Ncald
neurocalcin delta
chr10_+_116018213 0.422 ENSMUST00000063470.4
 Ptprr
protein tyrosine phosphatase, receptor type, R
chr8_-_109251698 0.401 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr1_-_134955847 0.397 ENSMUST00000168381.1
 Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr5_+_29195983 0.372 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
 Rnf32




ring finger protein 32




chr13_-_102906046 0.330 ENSMUST00000171791.1
 Mast4
microtubule associated serine/threonine kinase family member 4
chr3_+_121291725 0.314 ENSMUST00000039442.7
 Alg14
asparagine-linked glycosylation 14
chr16_-_50330987 0.308 ENSMUST00000114488.1
 Bbx
bobby sox homolog (Drosophila)
chr5_+_66968559 0.305 ENSMUST00000127184.1
 Limch1
LIM and calponin homology domains 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 1.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.2 0.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.6 GO:0019532 oxalate transport(GO:0019532)
0.0 0.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.2 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.2 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.2 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.0 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.6 GO:0008623 CHRAC(GO:0008623)
0.0 0.6 GO:0031672 A band(GO:0031672)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)

Gene overrepresentation in molecular_function category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 1.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)