Motif ID: Hoxa7_Hoxc8

Z-value: 0.378

Transcription factors associated with Hoxa7_Hoxc8:

Gene SymbolEntrez IDGene Name
Hoxa7 ENSMUSG00000038236.6 Hoxa7
Hoxc8 ENSMUSG00000001657.6 Hoxc8






Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa7_Hoxc8

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_-_143933089 1.173 ENSMUST00000087313.3
Dcx
doublecortin
chr15_-_67113909 1.073 ENSMUST00000092640.5
St3gal1
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr12_-_55014329 0.596 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr9_-_90255927 0.542 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr14_-_100149764 0.532 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr18_+_86711059 0.516 ENSMUST00000068423.3
Cbln2
cerebellin 2 precursor protein
chr2_+_69897255 0.510 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr4_+_102589687 0.478 ENSMUST00000097949.4
ENSMUST00000106901.1
Pde4b

phosphodiesterase 4B, cAMP specific

chrX_-_143933204 0.470 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr3_+_55782500 0.460 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr1_+_72284367 0.456 ENSMUST00000027380.5
ENSMUST00000141783.1
Tmem169

transmembrane protein 169

chr15_-_37458523 0.446 ENSMUST00000116445.2
Ncald
neurocalcin delta
chr10_+_116018213 0.422 ENSMUST00000063470.4
Ptprr
protein tyrosine phosphatase, receptor type, R
chr8_-_109251698 0.401 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr1_-_134955847 0.397 ENSMUST00000168381.1
Ppp1r12b
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr5_+_29195983 0.372 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
Rnf32




ring finger protein 32




chr13_-_102906046 0.330 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr3_+_121291725 0.314 ENSMUST00000039442.7
Alg14
asparagine-linked glycosylation 14
chr16_-_50330987 0.308 ENSMUST00000114488.1
Bbx
bobby sox homolog (Drosophila)
chr5_+_66968559 0.305 ENSMUST00000127184.1
Limch1
LIM and calponin homology domains 1
chr4_-_115133977 0.301 ENSMUST00000051400.7
Cyp4x1
cytochrome P450, family 4, subfamily x, polypeptide 1
chr18_+_23753708 0.301 ENSMUST00000115830.1
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr2_-_121235689 0.299 ENSMUST00000142400.1
Trp53bp1
transformation related protein 53 binding protein 1
chr1_-_126738167 0.296 ENSMUST00000160693.1
Nckap5
NCK-associated protein 5
chr13_-_102905740 0.294 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr14_-_108914237 0.258 ENSMUST00000100322.2
Slitrk1
SLIT and NTRK-like family, member 1
chr14_+_80000292 0.250 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr1_-_172027269 0.241 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr4_-_14621669 0.238 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chr10_+_37139558 0.229 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr4_-_82850721 0.220 ENSMUST00000139401.1
Zdhhc21
zinc finger, DHHC domain containing 21
chr1_-_134955908 0.218 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
Ppp1r12b


protein phosphatase 1, regulatory (inhibitor) subunit 12B


chr4_-_14621494 0.216 ENSMUST00000149633.1
Slc26a7
solute carrier family 26, member 7
chr6_-_30693676 0.204 ENSMUST00000169422.1
ENSMUST00000115131.1
ENSMUST00000115130.2
ENSMUST00000031810.8
Cep41



centrosomal protein 41



chr3_+_55461758 0.203 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr14_-_36919314 0.201 ENSMUST00000182797.1
Ccser2
coiled-coil serine rich 2
chr15_-_100425050 0.201 ENSMUST00000123461.1
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr7_+_38183217 0.194 ENSMUST00000165308.1
1600014C10Rik
RIKEN cDNA 1600014C10 gene
chr2_+_23069210 0.183 ENSMUST00000155602.1
Acbd5
acyl-Coenzyme A binding domain containing 5
chrX_+_166170449 0.168 ENSMUST00000130880.2
ENSMUST00000056410.4
ENSMUST00000096252.3
ENSMUST00000087169.4
Gemin8



gem (nuclear organelle) associated protein 8



chr10_-_117148474 0.167 ENSMUST00000020381.3
Frs2
fibroblast growth factor receptor substrate 2
chr4_+_108719649 0.166 ENSMUST00000178992.1
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr4_-_14621805 0.154 ENSMUST00000042221.7
Slc26a7
solute carrier family 26, member 7
chr18_+_32067729 0.151 ENSMUST00000025243.3
Iws1
IWS1 homolog (S. cerevisiae)
chr2_+_69897220 0.150 ENSMUST00000055758.9
ENSMUST00000112251.2
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr12_-_40248073 0.143 ENSMUST00000169926.1
Ifrd1
interferon-related developmental regulator 1
chr13_+_42681513 0.142 ENSMUST00000149235.1
Phactr1
phosphatase and actin regulator 1
chr9_+_113812547 0.139 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
Clasp2


CLIP associating protein 2


chr18_-_56975333 0.137 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chr4_+_100478806 0.130 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
Ube2u


ubiquitin-conjugating enzyme E2U (putative)


chr15_-_75905349 0.129 ENSMUST00000127550.1
Eef1d
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr2_-_33718789 0.124 ENSMUST00000130532.1
9430024E24Rik
RIKEN cDNA 9430024E24 gene
chr15_+_98571004 0.119 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr2_-_45117349 0.111 ENSMUST00000176438.2
Zeb2
zinc finger E-box binding homeobox 2
chr7_+_35802593 0.108 ENSMUST00000052454.2
E130304I02Rik
RIKEN cDNA E130304I02 gene
chrX_+_159303266 0.107 ENSMUST00000112491.1
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr12_+_71170589 0.105 ENSMUST00000129376.1
2700049A03Rik
RIKEN cDNA 2700049A03 gene
chr13_-_53473074 0.102 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr5_+_66968416 0.102 ENSMUST00000038188.7
Limch1
LIM and calponin homology domains 1
chr15_+_81744848 0.093 ENSMUST00000109554.1
Zc3h7b
zinc finger CCCH type containing 7B
chr17_-_29007925 0.087 ENSMUST00000009138.5
ENSMUST00000119274.1
Stk38

serine/threonine kinase 38

chr13_+_43785107 0.083 ENSMUST00000015540.2
Cd83
CD83 antigen
chr7_-_38019505 0.073 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr9_-_55919605 0.072 ENSMUST00000037408.8
Scaper
S phase cyclin A-associated protein in the ER
chr17_-_45659312 0.069 ENSMUST00000120717.1
Capn11
calpain 11
chr2_+_110597298 0.066 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr6_+_134640940 0.064 ENSMUST00000062755.8
Loh12cr1
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr9_-_79977782 0.063 ENSMUST00000093811.4
Filip1
filamin A interacting protein 1
chr16_-_45724600 0.049 ENSMUST00000096057.4
Tagln3
transgelin 3
chr6_+_37870786 0.046 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr18_-_75697639 0.045 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr11_-_82890541 0.040 ENSMUST00000092844.6
ENSMUST00000021033.9
ENSMUST00000018985.8
Rad51d


RAD51 homolog D


chrX_+_16619698 0.033 ENSMUST00000026013.5
Maoa
monoamine oxidase A
chr3_+_96645579 0.033 ENSMUST00000119365.1
ENSMUST00000029744.5
Itga10

integrin, alpha 10

chr19_-_53944621 0.031 ENSMUST00000135402.2
Bbip1
BBSome interacting protein 1
chr6_+_63255971 0.026 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr1_+_24177610 0.026 ENSMUST00000054588.8
Col9a1
collagen, type IX, alpha 1
chr13_-_81710937 0.019 ENSMUST00000161920.1
ENSMUST00000048993.5
Polr3g

polymerase (RNA) III (DNA directed) polypeptide G

chr13_+_24801657 0.018 ENSMUST00000019276.4
BC005537
cDNA sequence BC005537
chr3_-_86548268 0.014 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr13_+_24802020 0.012 ENSMUST00000155575.1
BC005537
cDNA sequence BC005537
chr7_+_126950687 0.010 ENSMUST00000106333.1
Sez6l2
seizure related 6 homolog like 2
chr10_-_128626464 0.006 ENSMUST00000026420.5
Rps26
ribosomal protein S26
chr6_+_145934113 0.005 ENSMUST00000032383.7
Sspn
sarcospan
chr7_-_83550258 0.002 ENSMUST00000177929.1
Gm10610
predicted gene 10610
chr8_-_106573461 0.001 ENSMUST00000073722.5
Gm10073
predicted pseudogene 10073

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 0.4 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 1.6 GO:0021860 pyramidal neuron development(GO:0021860)
0.1 0.6 GO:0019532 oxalate transport(GO:0019532)
0.1 0.2 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 1.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0015692 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.5 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.1 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.0 0.2 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.2 GO:0007351 tripartite regional subdivision(GO:0007351) anterior/posterior axis specification, embryo(GO:0008595)
0.0 0.1 GO:0032713 negative regulation of interleukin-4 production(GO:0032713)
0.0 0.0 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.0 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0008623 CHRAC(GO:0008623)
0.1 0.2 GO:0060187 cell pole(GO:0060187)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 0.6 GO:0031672 A band(GO:0031672)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.1 1.6 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.3 GO:0070330 aromatase activity(GO:0070330)
0.1 0.6 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0043015 gamma-tubulin binding(GO:0043015)