Motif ID: Hoxa9_Hoxb9

Z-value: 0.605

Transcription factors associated with Hoxa9_Hoxb9:

Gene SymbolEntrez IDGene Name
Hoxa9 ENSMUSG00000038227.9 Hoxa9
Hoxb9 ENSMUSG00000020875.8 Hoxb9



Activity profile for motif Hoxa9_Hoxb9.

activity profile for motif Hoxa9_Hoxb9


Sorted Z-values histogram for motif Hoxa9_Hoxb9

Sorted Z-values for motif Hoxa9_Hoxb9



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa9_Hoxb9

PNG image of the network

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Top targets:


Showing 1 to 20 of 109 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_-_57197435 2.071 ENSMUST00000111550.1
 Ablim1
actin-binding LIM protein 1
chr19_-_57197377 2.027 ENSMUST00000111546.1
 Ablim1
actin-binding LIM protein 1
chr5_-_73191848 1.779 ENSMUST00000176910.1
 Fryl
furry homolog-like (Drosophila)
chr6_+_49822710 1.434 ENSMUST00000031843.6
 Npy
neuropeptide Y
chr13_+_16014457 1.063 ENSMUST00000164993.1
 Inhba
inhibin beta-A
chr19_-_57197496 0.923 ENSMUST00000111544.1
 Ablim1
actin-binding LIM protein 1
chr6_-_143947092 0.793 ENSMUST00000144289.1
ENSMUST00000111748.1
 Sox5

SRY-box containing gene 5

chr5_-_66514815 0.763 ENSMUST00000161879.1
ENSMUST00000159357.1
 Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr9_+_92309362 0.736 ENSMUST00000098477.1
ENSMUST00000150594.1
 1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr6_-_143947061 0.733 ENSMUST00000124233.1
 Sox5
SRY-box containing gene 5
chr3_+_108591279 0.719 ENSMUST00000051145.8
ENSMUST00000139626.1
 Wdr47

WD repeat domain 47

chr19_-_57197556 0.645 ENSMUST00000099294.2
 Ablim1
actin-binding LIM protein 1
chr3_+_138065052 0.631 ENSMUST00000163080.2
 1110002E22Rik
RIKEN cDNA 1110002E22 gene
chr19_-_7341848 0.580 ENSMUST00000171393.1
 Mark2
MAP/microtubule affinity-regulating kinase 2
chr19_-_50678642 0.548 ENSMUST00000072685.6
ENSMUST00000164039.2
 Sorcs1

VPS10 domain receptor protein SORCS 1

chr19_+_44203265 0.532 ENSMUST00000026220.5
 Scd3
stearoyl-coenzyme A desaturase 3
chr19_-_56548013 0.500 ENSMUST00000182059.1
 Dclre1a
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr7_+_56050135 0.490 ENSMUST00000076226.6
 Herc2
hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 2
chr13_-_91388079 0.460 ENSMUST00000181054.1
 A830009L08Rik
RIKEN cDNA A830009L08 gene
chr1_+_66386968 0.448 ENSMUST00000145419.1
 Map2
microtubule-associated protein 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.5 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 1.8 GO:0090527 actin filament reorganization(GO:0090527)
0.2 1.5 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.3 1.4 GO:0019732 antifungal humoral response(GO:0019732)
0.2 1.1 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 0.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 0.6 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.1 0.5 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.0 0.5 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.0 0.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.1 0.4 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.4 GO:0007320 insemination(GO:0007320)
0.0 0.4 GO:0051452 intracellular pH reduction(GO:0051452)
0.1 0.3 GO:0097278 complement-dependent cytotoxicity(GO:0097278)
0.0 0.3 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.3 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.2 GO:1903056 melanocyte migration(GO:0097324) regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.0 0.2 GO:0032264 IMP salvage(GO:0032264)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.7 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.4 GO:0043195 terminal bouton(GO:0043195)
0.4 1.1 GO:0043512 inhibin A complex(GO:0043512)
0.1 0.5 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.4 GO:0060187 cell pole(GO:0060187)
0.0 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.4 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.3 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.3 GO:0071439 clathrin complex(GO:0071439)
0.0 0.3 GO:0002116 semaphorin receptor complex(GO:0002116)
0.0 0.3 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.1 GO:0032982 myosin filament(GO:0032982)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.3 GO:0003779 actin binding(GO:0003779)
0.1 1.6 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 1.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.8 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.0 0.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.1 0.6 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.1 0.5 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.0 0.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0032183 SUMO binding(GO:0032183)
0.1 0.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.4 GO:0008308 voltage-gated anion channel activity(GO:0008308)
0.0 0.4 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:0002135 CTP binding(GO:0002135)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)