Motif ID: Hoxb1

Z-value: 1.001


Transcription factors associated with Hoxb1:

Gene SymbolEntrez IDGene Name
Hoxb1 ENSMUSG00000018973.2 Hoxb1



Activity profile for motif Hoxb1.

activity profile for motif Hoxb1


Sorted Z-values histogram for motif Hoxb1

Sorted Z-values for motif Hoxb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 74 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_123982799 5.284 ENSMUST00000106437.1
 Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr1_+_153665274 5.023 ENSMUST00000152114.1
ENSMUST00000111812.1
 Rgs8

regulator of G-protein signaling 8

chr19_-_41743665 3.515 ENSMUST00000025993.3
 Slit1
slit homolog 1 (Drosophila)
chr1_+_127306706 3.125 ENSMUST00000171405.1
 Mgat5
mannoside acetylglucosaminyltransferase 5
chr7_+_73391160 2.413 ENSMUST00000128471.1
 Rgma
RGM domain family, member A
chr3_+_127633134 2.259 ENSMUST00000029587.7
 Neurog2
neurogenin 2
chrX_+_143518671 2.130 ENSMUST00000134402.1
 Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr2_+_65845833 1.808 ENSMUST00000053910.3
 Csrnp3
cysteine-serine-rich nuclear protein 3
chr10_+_4266323 1.779 ENSMUST00000045730.5
 Akap12
A kinase (PRKA) anchor protein (gravin) 12
chr1_-_119053339 1.748 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
 Gli2


GLI-Kruppel family member GLI2


chr8_-_8639363 1.678 ENSMUST00000152698.1
 Efnb2
ephrin B2
chr8_-_87959560 1.628 ENSMUST00000109655.2
 Zfp423
zinc finger protein 423
chr18_-_56562187 1.270 ENSMUST00000171844.2
 Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr18_-_56562215 1.243 ENSMUST00000170309.1
 Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr4_+_103114712 1.090 ENSMUST00000143417.1
 Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr1_-_119053619 1.074 ENSMUST00000062483.8
 Gli2
GLI-Kruppel family member GLI2
chr1_-_157412576 1.055 ENSMUST00000078308.6
ENSMUST00000139470.1
 Rasal2

RAS protein activator like 2

chr15_+_74516196 1.031 ENSMUST00000042035.9
 Bai1
brain-specific angiogenesis inhibitor 1
chr4_-_35845204 0.944 ENSMUST00000164772.1
ENSMUST00000065173.2
 Lingo2

leucine rich repeat and Ig domain containing 2

chr2_+_124610573 0.926 ENSMUST00000103239.3
ENSMUST00000103240.2
 Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.0 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.5 3.5 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 3.1 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.7 2.8 GO:0060032 notochord regression(GO:0060032)
0.0 2.5 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.2 2.4 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 2.3 GO:0021954 central nervous system neuron development(GO:0021954)
0.1 2.1 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.3 1.8 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.1 1.8 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.2 1.7 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 1.7 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580) negative regulation of small GTPase mediated signal transduction(GO:0051058)
0.2 1.0 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 0.8 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.1 0.8 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.1 0.8 GO:0043249 erythrocyte maturation(GO:0043249)
0.1 0.7 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.7 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.6 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)

Gene overrepresentation in cellular_component category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.0 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 2.8 GO:0097542 ciliary tip(GO:0097542)
0.0 2.4 GO:0031225 anchored component of membrane(GO:0031225)
0.2 1.7 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 1.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.7 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.7 GO:0030660 Golgi-associated vesicle membrane(GO:0030660)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.5 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.4 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.4 GO:0016235 aggresome(GO:0016235)
0.1 0.2 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 24 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.3 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.1 5.0 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.4 3.5 GO:0048495 Roundabout binding(GO:0048495)
0.8 3.2 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.6 3.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.2 2.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 2.3 GO:0070888 E-box binding(GO:0070888)
0.1 2.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 1.8 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 1.8 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.0 GO:0000049 tRNA binding(GO:0000049)
0.1 0.8 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.2 0.7 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 0.4 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.4 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.1 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.4 GO:0035497 cAMP response element binding(GO:0035497)