Motif ID: Hoxb13

Z-value: 0.971


Transcription factors associated with Hoxb13:

Gene SymbolEntrez IDGene Name
Hoxb13 ENSMUSG00000049604.3 Hoxb13



Activity profile for motif Hoxb13.

activity profile for motif Hoxb13


Sorted Z-values histogram for motif Hoxb13

Sorted Z-values for motif Hoxb13



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb13

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_35074485 0.941 ENSMUST00000007259.3
 Ly6g6d
lymphocyte antigen 6 complex, locus G6D
chr5_-_66514815 0.900 ENSMUST00000161879.1
ENSMUST00000159357.1
 Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr5_-_118155379 0.740 ENSMUST00000049474.7
 Fbxw8
F-box and WD-40 domain protein 8
chr13_-_113663670 0.738 ENSMUST00000054650.4
 Hspb3
heat shock protein 3
chr16_+_78930940 0.694 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
 Chodl


chondrolectin


chr3_+_134236483 0.681 ENSMUST00000181904.1
ENSMUST00000053048.9
 Cxxc4

CXXC finger 4

chr13_-_91388079 0.671 ENSMUST00000181054.1
 A830009L08Rik
RIKEN cDNA A830009L08 gene
chr2_-_172043466 0.646 ENSMUST00000087950.3
 Cbln4
cerebellin 4 precursor protein
chr4_-_6990774 0.625 ENSMUST00000039987.3
 Tox
thymocyte selection-associated high mobility group box
chr15_+_25742314 0.617 ENSMUST00000135981.1
 Myo10
myosin X
chr19_-_57197496 0.609 ENSMUST00000111544.1
 Ablim1
actin-binding LIM protein 1
chr9_-_63711969 0.596 ENSMUST00000154323.1
 Smad3
SMAD family member 3
chr15_+_83791939 0.590 ENSMUST00000172115.1
ENSMUST00000172398.1
 Mpped1

metallophosphoesterase domain containing 1

chr4_+_102570065 0.585 ENSMUST00000097950.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr19_-_57197435 0.580 ENSMUST00000111550.1
 Ablim1
actin-binding LIM protein 1
chr9_-_64022043 0.575 ENSMUST00000041029.5
 Smad6
SMAD family member 6
chr1_-_56969827 0.572 ENSMUST00000176759.1
 Satb2
special AT-rich sequence binding protein 2
chr14_-_70323783 0.569 ENSMUST00000151011.1
 Slc39a14
solute carrier family 39 (zinc transporter), member 14
chrX_+_142825698 0.567 ENSMUST00000112888.1
 Tmem164
transmembrane protein 164
chr9_+_34904913 0.565 ENSMUST00000045091.6
 Kirrel3
kin of IRRE like 3 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 258 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.7 GO:0030032 lamellipodium assembly(GO:0030032)
0.1 1.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 1.2 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 1.1 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.1 GO:0009060 aerobic respiration(GO:0009060)
0.0 1.1 GO:0050821 protein stabilization(GO:0050821)
0.0 0.9 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.0 0.8 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.2 0.7 GO:0006597 spermine biosynthetic process(GO:0006597)
0.2 0.7 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.7 GO:0010388 cullin deneddylation(GO:0010388)
0.0 0.7 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.2 0.6 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 0.6 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.2 0.6 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.1 0.6 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.1 0.6 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.6 GO:0002121 inter-male aggressive behavior(GO:0002121)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 116 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.4 GO:0016459 myosin complex(GO:0016459)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 1.2 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 1.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 1.1 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.9 GO:0008180 COP9 signalosome(GO:0008180)
0.3 0.8 GO:1990393 3M complex(GO:1990393)
0.0 0.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.8 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.7 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.7 GO:0005844 polysome(GO:0005844)
0.2 0.6 GO:0072534 perineuronal net(GO:0072534)
0.2 0.6 GO:0060187 cell pole(GO:0060187)
0.1 0.6 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.1 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.6 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 156 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 1.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 1.2 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 1.2 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.1 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.9 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 0.9 GO:0030507 spectrin binding(GO:0030507)
0.0 0.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 0.8 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.8 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.1 0.8 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.8 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 0.7 GO:0019808 polyamine binding(GO:0019808)
0.2 0.7 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.7 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.7 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)