Motif ID: Hoxb2_Dlx2
Z-value: 1.325
Transcription factors associated with Hoxb2_Dlx2:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Dlx2 | ENSMUSG00000023391.7 | Dlx2 |
| Hoxb2 | ENSMUSG00000075588.5 | Hoxb2 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Dlx2 | mm10_v2_chr2_-_71546745_71546758 | 0.85 | 1.4e-04 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.4 | 10.1 | GO:0090425 | hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979) |
| 3.3 | 9.9 | GO:0021893 | cerebral cortex GABAergic interneuron fate commitment(GO:0021893) |
| 1.1 | 6.8 | GO:0006957 | complement activation, alternative pathway(GO:0006957) |
| 0.9 | 3.5 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.8 | 2.4 | GO:0072092 | ureteric bud invasion(GO:0072092) |
| 0.8 | 2.3 | GO:0008228 | opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428) |
| 0.7 | 2.0 | GO:0060166 | olfactory pit development(GO:0060166) |
| 0.6 | 2.6 | GO:0060729 | intestinal epithelial structure maintenance(GO:0060729) |
| 0.5 | 1.0 | GO:0072179 | nephric duct formation(GO:0072179) |
| 0.5 | 1.0 | GO:0071599 | otic vesicle development(GO:0071599) |
| 0.5 | 14.9 | GO:0007638 | mechanosensory behavior(GO:0007638) |
| 0.5 | 1.0 | GO:0030321 | transepithelial chloride transport(GO:0030321) |
| 0.5 | 1.9 | GO:0006538 | glutamate catabolic process(GO:0006538) |
| 0.5 | 3.7 | GO:0033353 | S-adenosylmethionine cycle(GO:0033353) |
| 0.5 | 6.4 | GO:0051482 | positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482) |
| 0.5 | 3.2 | GO:0019532 | oxalate transport(GO:0019532) |
| 0.4 | 1.8 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
| 0.4 | 2.6 | GO:0006123 | mitochondrial electron transport, cytochrome c to oxygen(GO:0006123) |
| 0.4 | 3.6 | GO:0043129 | surfactant homeostasis(GO:0043129) |
| 0.4 | 1.2 | GO:0035633 | maintenance of blood-brain barrier(GO:0035633) |
| 0.4 | 1.2 | GO:0003278 | apoptotic process involved in heart morphogenesis(GO:0003278) regulation of vascular wound healing(GO:0061043) glomerular mesangial cell differentiation(GO:0072008) glomerular mesangial cell development(GO:0072144) |
| 0.4 | 1.1 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
| 0.3 | 1.4 | GO:1900272 | negative regulation of long-term synaptic potentiation(GO:1900272) |
| 0.3 | 10.5 | GO:0032728 | positive regulation of interferon-beta production(GO:0032728) |
| 0.3 | 1.9 | GO:1990118 | sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118) |
| 0.3 | 1.6 | GO:0042795 | snRNA transcription from RNA polymerase II promoter(GO:0042795) |
| 0.3 | 1.6 | GO:0036233 | glycine import(GO:0036233) |
| 0.2 | 5.3 | GO:1902259 | regulation of delayed rectifier potassium channel activity(GO:1902259) |
| 0.2 | 3.4 | GO:0021891 | olfactory bulb interneuron development(GO:0021891) |
| 0.2 | 1.3 | GO:0072513 | positive regulation of secondary heart field cardioblast proliferation(GO:0072513) |
| 0.2 | 0.8 | GO:0072592 | regulation of integrin biosynthetic process(GO:0045113) oxygen metabolic process(GO:0072592) |
| 0.2 | 0.6 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
| 0.2 | 0.6 | GO:0061153 | trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) |
| 0.2 | 1.5 | GO:0007406 | negative regulation of neuroblast proliferation(GO:0007406) |
| 0.2 | 1.5 | GO:0045199 | maintenance of epithelial cell apical/basal polarity(GO:0045199) |
| 0.2 | 1.9 | GO:0033280 | response to vitamin D(GO:0033280) |
| 0.2 | 2.9 | GO:2000251 | positive regulation of actin cytoskeleton reorganization(GO:2000251) |
| 0.2 | 0.9 | GO:2000774 | positive regulation of cellular senescence(GO:2000774) |
| 0.2 | 0.3 | GO:0071504 | response to heparin(GO:0071503) cellular response to heparin(GO:0071504) |
| 0.1 | 1.7 | GO:0060081 | membrane hyperpolarization(GO:0060081) |
| 0.1 | 0.9 | GO:0032049 | cardiolipin biosynthetic process(GO:0032049) |
| 0.1 | 2.3 | GO:0001504 | neurotransmitter uptake(GO:0001504) |
| 0.1 | 1.0 | GO:0060013 | righting reflex(GO:0060013) |
| 0.1 | 0.4 | GO:1905065 | cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344) regulation of vascular smooth muscle cell differentiation(GO:1905063) positive regulation of vascular smooth muscle cell differentiation(GO:1905065) |
| 0.1 | 7.1 | GO:0022900 | electron transport chain(GO:0022900) |
| 0.1 | 0.7 | GO:0052695 | cellular glucuronidation(GO:0052695) |
| 0.1 | 0.2 | GO:0061144 | alveolar secondary septum development(GO:0061144) |
| 0.1 | 1.3 | GO:2000671 | regulation of motor neuron apoptotic process(GO:2000671) |
| 0.1 | 0.8 | GO:0016584 | nucleosome positioning(GO:0016584) |
| 0.1 | 3.1 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.1 | 0.8 | GO:0045602 | negative regulation of endothelial cell differentiation(GO:0045602) |
| 0.1 | 0.4 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
| 0.1 | 2.0 | GO:0006953 | acute-phase response(GO:0006953) |
| 0.1 | 0.4 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.1 | 2.4 | GO:0071108 | protein K48-linked deubiquitination(GO:0071108) |
| 0.1 | 1.9 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.1 | 2.1 | GO:0001886 | endothelial cell morphogenesis(GO:0001886) |
| 0.1 | 0.7 | GO:1900194 | negative regulation of oocyte maturation(GO:1900194) |
| 0.1 | 0.5 | GO:2000253 | positive regulation of feeding behavior(GO:2000253) |
| 0.1 | 2.6 | GO:0002089 | lens morphogenesis in camera-type eye(GO:0002089) |
| 0.1 | 0.3 | GO:0010871 | negative regulation of receptor biosynthetic process(GO:0010871) |
| 0.1 | 1.1 | GO:1901673 | regulation of mitotic spindle assembly(GO:1901673) |
| 0.1 | 8.1 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 0.1 | 0.3 | GO:0035752 | lysosomal lumen pH elevation(GO:0035752) |
| 0.1 | 0.5 | GO:0045218 | zonula adherens maintenance(GO:0045218) |
| 0.1 | 1.5 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 1.7 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.1 | 1.6 | GO:0010614 | negative regulation of cardiac muscle hypertrophy(GO:0010614) |
| 0.1 | 0.4 | GO:1900170 | negative regulation of glucocorticoid mediated signaling pathway(GO:1900170) |
| 0.1 | 0.4 | GO:0044034 | negative stranded viral RNA replication(GO:0039689) multi-organism biosynthetic process(GO:0044034) |
| 0.1 | 0.9 | GO:0015937 | coenzyme A biosynthetic process(GO:0015937) |
| 0.1 | 0.5 | GO:0060355 | positive regulation of cell adhesion molecule production(GO:0060355) |
| 0.1 | 0.5 | GO:0097460 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) |
| 0.1 | 0.8 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 0.1 | 1.5 | GO:0071398 | cellular response to fatty acid(GO:0071398) |
| 0.1 | 1.1 | GO:0006907 | pinocytosis(GO:0006907) |
| 0.1 | 0.2 | GO:0090526 | response to leucine(GO:0043201) cellular response to leucine(GO:0071233) regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
| 0.0 | 0.3 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
| 0.0 | 0.3 | GO:0002361 | CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361) |
| 0.0 | 0.1 | GO:0086023 | adrenergic receptor signaling pathway involved in heart process(GO:0086023) |
| 0.0 | 1.4 | GO:0031365 | N-terminal protein amino acid modification(GO:0031365) |
| 0.0 | 3.8 | GO:0030168 | platelet activation(GO:0030168) |
| 0.0 | 1.1 | GO:0071384 | cellular response to corticosteroid stimulus(GO:0071384) cellular response to glucocorticoid stimulus(GO:0071385) |
| 0.0 | 0.2 | GO:0021780 | oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780) |
| 0.0 | 1.4 | GO:0010972 | negative regulation of G2/M transition of mitotic cell cycle(GO:0010972) |
| 0.0 | 1.6 | GO:0046676 | negative regulation of insulin secretion(GO:0046676) |
| 0.0 | 0.6 | GO:0048387 | negative regulation of retinoic acid receptor signaling pathway(GO:0048387) |
| 0.0 | 3.1 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.0 | 0.3 | GO:0070475 | rRNA base methylation(GO:0070475) |
| 0.0 | 0.1 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
| 0.0 | 0.7 | GO:0033194 | response to hydroperoxide(GO:0033194) |
| 0.0 | 5.2 | GO:0030833 | regulation of actin filament polymerization(GO:0030833) |
| 0.0 | 0.3 | GO:0046085 | adenosine metabolic process(GO:0046085) |
| 0.0 | 0.2 | GO:0021794 | rhombomere development(GO:0021546) thalamus development(GO:0021794) |
| 0.0 | 1.9 | GO:0010811 | positive regulation of cell-substrate adhesion(GO:0010811) |
| 0.0 | 0.2 | GO:0045974 | miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974) |
| 0.0 | 0.2 | GO:0035735 | intraciliary transport involved in cilium morphogenesis(GO:0035735) |
| 0.0 | 0.4 | GO:0045063 | T-helper 1 cell differentiation(GO:0045063) |
| 0.0 | 0.2 | GO:0097186 | amelogenesis(GO:0097186) |
| 0.0 | 0.5 | GO:0061014 | positive regulation of mRNA catabolic process(GO:0061014) |
| 0.0 | 0.1 | GO:0060050 | positive regulation of protein glycosylation(GO:0060050) |
| 0.0 | 0.2 | GO:0034308 | fatty acid elongation(GO:0030497) primary alcohol metabolic process(GO:0034308) |
| 0.0 | 0.2 | GO:0033572 | transferrin transport(GO:0033572) |
| 0.0 | 0.4 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.0 | 0.3 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.0 | 0.5 | GO:0034723 | DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723) |
| 0.0 | 0.5 | GO:0050873 | brown fat cell differentiation(GO:0050873) |
| 0.0 | 0.2 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.0 | 0.3 | GO:0002237 | response to molecule of bacterial origin(GO:0002237) response to lipopolysaccharide(GO:0032496) |
| 0.0 | 0.5 | GO:0000184 | nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184) |
| 0.0 | 0.4 | GO:0061028 | establishment of endothelial barrier(GO:0061028) |
| 0.0 | 0.3 | GO:0032611 | interleukin-1 beta production(GO:0032611) |
| 0.0 | 0.2 | GO:0015701 | bicarbonate transport(GO:0015701) |
| 0.0 | 0.1 | GO:0006390 | transcription from mitochondrial promoter(GO:0006390) |
| 0.0 | 0.5 | GO:0010633 | negative regulation of epithelial cell migration(GO:0010633) |
| 0.0 | 2.3 | GO:0016042 | lipid catabolic process(GO:0016042) |
| 0.0 | 0.4 | GO:0034605 | cellular response to heat(GO:0034605) |
| 0.0 | 0.3 | GO:0051591 | response to cAMP(GO:0051591) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 4.4 | GO:0071953 | elastic fiber(GO:0071953) |
| 1.0 | 4.8 | GO:0033093 | Weibel-Palade body(GO:0033093) |
| 0.4 | 2.4 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.3 | 2.6 | GO:0005751 | mitochondrial respiratory chain complex IV(GO:0005751) |
| 0.3 | 2.9 | GO:0071439 | clathrin complex(GO:0071439) |
| 0.3 | 3.1 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.2 | 3.5 | GO:0043205 | fibril(GO:0043205) |
| 0.2 | 0.8 | GO:0071438 | NADPH oxidase complex(GO:0043020) invadopodium membrane(GO:0071438) |
| 0.2 | 0.6 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
| 0.2 | 2.4 | GO:0000124 | SAGA complex(GO:0000124) |
| 0.1 | 2.3 | GO:0016010 | dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665) |
| 0.1 | 8.5 | GO:0070469 | respiratory chain(GO:0070469) |
| 0.1 | 1.7 | GO:0005614 | interstitial matrix(GO:0005614) |
| 0.1 | 0.5 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.1 | 0.3 | GO:0035867 | integrin alphav-beta5 complex(GO:0034684) alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) |
| 0.1 | 0.4 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.1 | 4.1 | GO:0030672 | synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501) |
| 0.1 | 0.8 | GO:0000815 | ESCRT III complex(GO:0000815) |
| 0.1 | 7.3 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.1 | 0.4 | GO:0061689 | paranodal junction(GO:0033010) tricellular tight junction(GO:0061689) |
| 0.1 | 0.4 | GO:0070695 | FHF complex(GO:0070695) |
| 0.1 | 0.8 | GO:0005662 | DNA replication factor A complex(GO:0005662) |
| 0.1 | 0.2 | GO:0030015 | CCR4-NOT core complex(GO:0030015) |
| 0.0 | 1.8 | GO:0001750 | photoreceptor outer segment(GO:0001750) |
| 0.0 | 0.3 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.0 | 1.7 | GO:0032281 | voltage-gated calcium channel complex(GO:0005891) AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 2.7 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.0 | 1.2 | GO:0055038 | recycling endosome membrane(GO:0055038) |
| 0.0 | 1.4 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.0 | 1.3 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 0.5 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
| 0.0 | 0.2 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.0 | 2.0 | GO:0055037 | recycling endosome(GO:0055037) |
| 0.0 | 0.3 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 1.0 | GO:0032420 | stereocilium(GO:0032420) |
| 0.0 | 0.2 | GO:0035068 | micro-ribonucleoprotein complex(GO:0035068) |
| 0.0 | 1.2 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.0 | 0.3 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.0 | 1.3 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 1.5 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.4 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.0 | 1.2 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.2 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.0 | 0.2 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.0 | 0.5 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 1.6 | GO:0016605 | PML body(GO:0016605) |
| 0.0 | 0.2 | GO:0070419 | nonhomologous end joining complex(GO:0070419) |
| 0.0 | 0.3 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 1.1 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 1.8 | GO:0032993 | protein-DNA complex(GO:0032993) |
| 0.0 | 0.2 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.0 | 0.4 | GO:0080008 | Cul4-RING E3 ubiquitin ligase complex(GO:0080008) |
| 0.0 | 0.2 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.0 | 1.3 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.0 | 0.0 | GO:0034274 | Atg12-Atg5-Atg16 complex(GO:0034274) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.3 | 6.8 | GO:0001851 | complement component C3b binding(GO:0001851) |
| 1.3 | 10.1 | GO:0050693 | LBD domain binding(GO:0050693) |
| 0.7 | 3.5 | GO:0005314 | high-affinity glutamate transmembrane transporter activity(GO:0005314) |
| 0.5 | 4.8 | GO:0019865 | immunoglobulin binding(GO:0019865) |
| 0.5 | 3.7 | GO:0004013 | adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802) |
| 0.5 | 2.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
| 0.4 | 2.0 | GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity(GO:0004030) |
| 0.3 | 2.0 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
| 0.3 | 1.6 | GO:0019960 | C-X3-C chemokine binding(GO:0019960) |
| 0.3 | 7.0 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.3 | 3.2 | GO:0019531 | oxalate transmembrane transporter activity(GO:0019531) |
| 0.3 | 0.8 | GO:0030171 | voltage-gated proton channel activity(GO:0030171) |
| 0.3 | 1.9 | GO:0004351 | glutamate decarboxylase activity(GO:0004351) |
| 0.3 | 1.6 | GO:0015375 | glycine:sodium symporter activity(GO:0015375) |
| 0.2 | 1.9 | GO:0005451 | monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386) |
| 0.2 | 3.6 | GO:0051428 | peptide hormone receptor binding(GO:0051428) |
| 0.2 | 1.1 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
| 0.2 | 0.8 | GO:0032422 | purine-rich negative regulatory element binding(GO:0032422) |
| 0.2 | 1.5 | GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162) |
| 0.2 | 0.9 | GO:0004594 | pantothenate kinase activity(GO:0004594) |
| 0.2 | 0.9 | GO:0008808 | cardiolipin synthase activity(GO:0008808) phosphatidyltransferase activity(GO:0030572) |
| 0.2 | 2.4 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.2 | 1.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.2 | 2.5 | GO:0001968 | fibronectin binding(GO:0001968) |
| 0.2 | 2.3 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
| 0.2 | 7.6 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
| 0.2 | 2.4 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.2 | 1.7 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.1 | 2.2 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 4.5 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
| 0.1 | 1.0 | GO:0045028 | G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028) |
| 0.1 | 6.7 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 2.5 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.1 | 1.1 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.1 | 2.0 | GO:0005044 | scavenger receptor activity(GO:0005044) |
| 0.1 | 6.3 | GO:0008528 | G-protein coupled peptide receptor activity(GO:0008528) |
| 0.1 | 2.2 | GO:0004435 | phosphatidylinositol phospholipase C activity(GO:0004435) |
| 0.1 | 1.0 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.1 | 3.1 | GO:0005251 | delayed rectifier potassium channel activity(GO:0005251) |
| 0.1 | 0.8 | GO:0038036 | sphingosine-1-phosphate receptor activity(GO:0038036) |
| 0.1 | 1.3 | GO:0004861 | cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861) |
| 0.1 | 0.4 | GO:0038049 | glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051) |
| 0.1 | 7.2 | GO:0002039 | p53 binding(GO:0002039) |
| 0.1 | 1.9 | GO:0070064 | proline-rich region binding(GO:0070064) |
| 0.1 | 0.2 | GO:0019166 | trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166) |
| 0.1 | 0.6 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
| 0.1 | 0.9 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
| 0.1 | 0.5 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.1 | 8.1 | GO:0001078 | transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078) |
| 0.1 | 0.3 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
| 0.1 | 2.0 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
| 0.1 | 1.3 | GO:0008545 | JUN kinase kinase activity(GO:0008545) |
| 0.1 | 20.8 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 0.4 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.1 | 0.5 | GO:0008329 | signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187) |
| 0.1 | 0.2 | GO:0008510 | sodium:bicarbonate symporter activity(GO:0008510) |
| 0.1 | 0.2 | GO:0000774 | adenyl-nucleotide exchange factor activity(GO:0000774) |
| 0.1 | 0.5 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.0 | 0.4 | GO:0016846 | carbon-sulfur lyase activity(GO:0016846) |
| 0.0 | 0.9 | GO:0016208 | AMP binding(GO:0016208) |
| 0.0 | 3.0 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.0 | 1.7 | GO:0005245 | voltage-gated calcium channel activity(GO:0005245) |
| 0.0 | 0.2 | GO:0022821 | calcium, potassium:sodium antiporter activity(GO:0008273) potassium ion antiporter activity(GO:0022821) |
| 0.0 | 3.3 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.0 | 0.9 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 0.3 | GO:1990405 | protein antigen binding(GO:1990405) |
| 0.0 | 0.1 | GO:0042030 | ATPase inhibitor activity(GO:0042030) |
| 0.0 | 1.4 | GO:0016684 | oxidoreductase activity, acting on peroxide as acceptor(GO:0016684) |
| 0.0 | 0.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.5 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.6 | GO:0005164 | tumor necrosis factor receptor binding(GO:0005164) |
| 0.0 | 0.3 | GO:0004623 | phospholipase A2 activity(GO:0004623) |
| 0.0 | 0.3 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.0 | 1.7 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 0.3 | GO:0008253 | 5'-nucleotidase activity(GO:0008253) |
| 0.0 | 0.6 | GO:0005504 | fatty acid binding(GO:0005504) |
| 0.0 | 0.8 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 0.2 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 1.4 | GO:0030165 | PDZ domain binding(GO:0030165) |
| 0.0 | 0.8 | GO:0030674 | protein binding, bridging(GO:0030674) |
| 0.0 | 1.7 | GO:0008276 | protein methyltransferase activity(GO:0008276) |
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