Motif ID: Hoxb3

Z-value: 1.397


Transcription factors associated with Hoxb3:

Gene SymbolEntrez IDGene Name
Hoxb3 ENSMUSG00000048763.5 Hoxb3



Activity profile for motif Hoxb3.

activity profile for motif Hoxb3


Sorted Z-values histogram for motif Hoxb3

Sorted Z-values for motif Hoxb3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb3

PNG image of the network

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Top targets:


Showing 1 to 20 of 126 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_170009892 5.628 ENSMUST00000180251.1
 Gm21887
predicted gene, 21887
chrY_+_90785442 4.661 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
 Erdr1


erythroid differentiation regulator 1


chr9_-_54661870 4.473 ENSMUST00000034822.5
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr9_-_120068263 3.890 ENSMUST00000064165.3
ENSMUST00000177637.1
 Cx3cr1

chemokine (C-X3-C) receptor 1

chr8_+_66386292 3.884 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr13_+_94083490 3.612 ENSMUST00000156071.1
 Lhfpl2
lipoma HMGIC fusion partner-like 2
chr7_+_57387304 3.483 ENSMUST00000085241.5
 Gm9962
predicted gene 9962
chr12_+_112760652 3.455 ENSMUST00000063888.3
 Pld4
phospholipase D family, member 4
chr13_-_92030897 3.450 ENSMUST00000149630.1
 Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr14_+_99298652 3.440 ENSMUST00000005279.6
 Klf5
Kruppel-like factor 5
chrY_+_90784738 3.380 ENSMUST00000179483.1
 Erdr1
erythroid differentiation regulator 1
chr2_+_19371636 3.366 ENSMUST00000023856.8
 Msrb2
methionine sulfoxide reductase B2
chr17_-_45659312 3.142 ENSMUST00000120717.1
 Capn11
calpain 11
chr2_+_116067213 3.139 ENSMUST00000152412.1
 G630016G05Rik
RIKEN cDNA G630016G05 gene
chr18_+_12741324 2.963 ENSMUST00000115857.2
ENSMUST00000121018.1
ENSMUST00000119108.1
 Cabyr


calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)


chr3_-_121263314 2.712 ENSMUST00000029777.7
 Tmem56
transmembrane protein 56
chr2_-_116067391 2.614 ENSMUST00000140185.1
 2700033N17Rik
RIKEN cDNA 2700033N17 gene
chrX_+_170010744 2.438 ENSMUST00000178789.1
 Gm21887
predicted gene, 21887
chr19_+_3323301 2.430 ENSMUST00000025835.4
 Cpt1a
carnitine palmitoyltransferase 1a, liver
chr10_-_8886033 2.364 ENSMUST00000015449.5
 Sash1
SAM and SH3 domain containing 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.1 6.1 GO:0035019 somatic stem cell population maintenance(GO:0035019)
1.0 5.2 GO:0030091 protein repair(GO:0030091)
1.0 3.9 GO:1900272 negative regulation of long-term synaptic potentiation(GO:1900272)
0.2 3.9 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 3.5 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 3.5 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.5 3.4 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.2 3.1 GO:0048240 sperm capacitation(GO:0048240)
0.7 2.9 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 2.6 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.4 2.5 GO:0019532 oxalate transport(GO:0019532)
0.8 2.4 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.2 2.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 2.4 GO:0006828 manganese ion transport(GO:0006828)
0.6 1.9 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.3 1.9 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.9 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.4 1.5 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.3 1.5 GO:0007386 compartment pattern specification(GO:0007386)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.2 7.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 3.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 3.8 GO:0001669 acrosomal vesicle(GO:0001669)
0.2 3.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 2.9 GO:0043205 fibril(GO:0043205)
0.1 2.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.1 2.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 2.2 GO:0005801 cis-Golgi network(GO:0005801)
0.0 2.2 GO:0005802 trans-Golgi network(GO:0005802)
0.2 1.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.9 GO:0055037 recycling endosome(GO:0055037)
0.2 1.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.9 GO:0070469 respiratory chain(GO:0070469)
0.0 0.8 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.5 GO:0044295 axonal growth cone(GO:0044295)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 5.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.5 5.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.8 3.9 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.4 3.5 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 3.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 3.1 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 3.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 3.0 GO:0042287 MHC protein binding(GO:0042287)
0.6 2.9 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 2.8 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.2 2.5 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.5 2.4 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
0.2 2.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 2.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.2 1.9 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.2 1.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 1.9 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.5 1.5 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.4 1.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.4 1.5 GO:0008410 CoA-transferase activity(GO:0008410)