Motif ID: Hoxb5

Z-value: 0.833


Transcription factors associated with Hoxb5:

Gene SymbolEntrez IDGene Name
Hoxb5 ENSMUSG00000038700.3 Hoxb5



Activity profile for motif Hoxb5.

activity profile for motif Hoxb5


Sorted Z-values histogram for motif Hoxb5

Sorted Z-values for motif Hoxb5



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb5

PNG image of the network

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Top targets:


Showing 1 to 20 of 91 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_-_63927434 1.972 ENSMUST00000079279.3
 Gm10118
predicted gene 10118
chr3_-_103737995 1.802 ENSMUST00000029440.8
 Olfml3
olfactomedin-like 3
chrX_-_60893430 1.675 ENSMUST00000135107.2
 Sox3
SRY-box containing gene 3
chr4_+_11704439 1.266 ENSMUST00000108304.2
 Gem
GTP binding protein (gene overexpressed in skeletal muscle)
chrX_-_165327376 1.235 ENSMUST00000058787.8
 Glra2
glycine receptor, alpha 2 subunit
chr4_-_131821516 1.085 ENSMUST00000097860.2
 Ptpru
protein tyrosine phosphatase, receptor type, U
chr17_+_31386218 1.073 ENSMUST00000047168.5
 Pde9a
phosphodiesterase 9A
chr17_+_31386244 1.029 ENSMUST00000134525.1
ENSMUST00000127929.1
 Pde9a

phosphodiesterase 9A

chr7_-_119895697 1.002 ENSMUST00000059851.6
 Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr4_+_126103940 0.965 ENSMUST00000116286.2
ENSMUST00000094761.4
ENSMUST00000139524.1
 Stk40


serine/threonine kinase 40


chrX_-_72656135 0.911 ENSMUST00000055966.6
 Gabra3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr4_+_86053887 0.870 ENSMUST00000107178.2
ENSMUST00000048885.5
ENSMUST00000141889.1
ENSMUST00000120678.1
 Adamtsl1



ADAMTS-like 1



chr7_+_3390629 0.813 ENSMUST00000182222.1
 Cacng8
calcium channel, voltage-dependent, gamma subunit 8
chr12_-_78980758 0.810 ENSMUST00000174072.1
 Tmem229b
transmembrane protein 229B
chr4_-_141874879 0.781 ENSMUST00000036854.3
 Efhd2
EF hand domain containing 2
chr2_+_158667119 0.766 ENSMUST00000045503.4
 Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr10_-_62143906 0.717 ENSMUST00000141724.1
ENSMUST00000150057.1
 2010107G23Rik

RIKEN cDNA 2010107G23 gene

chr9_-_35558522 0.676 ENSMUST00000034612.5
 Ddx25
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr7_-_119896285 0.609 ENSMUST00000106519.1
 Dcun1d3
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr4_+_14864076 0.582 ENSMUST00000029875.3
 Tmem55a
transmembrane protein 55A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 35 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 1.7 GO:0007530 sex determination(GO:0007530)
0.1 1.6 GO:0010225 response to UV-C(GO:0010225)
0.0 1.3 GO:0051310 metaphase plate congression(GO:0051310)
0.3 1.2 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.2 1.2 GO:0071361 cellular response to zinc ion(GO:0071294) cellular response to ethanol(GO:0071361)
0.0 1.0 GO:0003016 respiratory system process(GO:0003016)
0.0 0.9 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.2 0.8 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0 0.8 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.7 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.6 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.1 0.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 0.4 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.4 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.0 0.4 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.4 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.4 GO:0030213 hyaluronan biosynthetic process(GO:0030213)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 1.4 GO:0043204 perikaryon(GO:0043204)
0.0 1.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.1 0.7 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.3 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.1 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 1.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 1.6 GO:0097602 cullin family protein binding(GO:0097602)
0.4 1.2 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.2 1.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 1.0 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.1 0.9 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.8 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.0 0.8 GO:0019003 GDP binding(GO:0019003)
0.2 0.7 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.2 0.6 GO:0034597 phosphatidylinositol-4,5-bisphosphate 4-phosphatase activity(GO:0034597)
0.0 0.6 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 0.4 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.3 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.3 GO:0035939 microsatellite binding(GO:0035939)
0.0 0.3 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.3 GO:0016670 oxidoreductase activity, acting on a sulfur group of donors, oxygen as acceptor(GO:0016670)
0.0 0.3 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.3 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)