Motif ID: Hoxb6

Z-value: 0.467


Transcription factors associated with Hoxb6:

Gene SymbolEntrez IDGene Name
Hoxb6 ENSMUSG00000000690.4 Hoxb6



Activity profile for motif Hoxb6.

activity profile for motif Hoxb6


Sorted Z-values histogram for motif Hoxb6

Sorted Z-values for motif Hoxb6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_92030897 1.448 ENSMUST00000149630.1
 Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr12_-_119238794 0.749 ENSMUST00000026360.8
 Itgb8
integrin beta 8
chr9_+_92309362 0.644 ENSMUST00000098477.1
ENSMUST00000150594.1
 1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr15_+_34306666 0.625 ENSMUST00000163455.2
ENSMUST00000022947.5
 Matn2

matrilin 2

chr1_-_22805994 0.598 ENSMUST00000097808.4
 Rims1
regulating synaptic membrane exocytosis 1
chr9_-_70141484 0.464 ENSMUST00000034749.8
 Fam81a
family with sequence similarity 81, member A
chr3_-_94412883 0.387 ENSMUST00000181305.1
 1700040D17Rik
RIKEN cDNA 1700040D17 gene
chr8_-_77610668 0.378 ENSMUST00000141202.1
ENSMUST00000152168.1
 Tmem184c

transmembrane protein 184C

chr2_-_125859139 0.332 ENSMUST00000110463.1
ENSMUST00000028635.5
 Cops2

COP9 (constitutive photomorphogenic) homolog, subunit 2 (Arabidopsis thaliana)

chr10_-_58675631 0.307 ENSMUST00000003312.4
 Edar
ectodysplasin-A receptor
chr8_-_77610597 0.297 ENSMUST00000034030.8
 Tmem184c
transmembrane protein 184C
chr19_+_25406661 0.278 ENSMUST00000146647.1
 Kank1
KN motif and ankyrin repeat domains 1
chrX_-_143933089 0.275 ENSMUST00000087313.3
 Dcx
doublecortin
chr11_-_69795930 0.258 ENSMUST00000045971.8
 Chrnb1
cholinergic receptor, nicotinic, beta polypeptide 1 (muscle)
chr8_+_13435459 0.220 ENSMUST00000167071.1
ENSMUST00000167505.1
 Tmem255b

transmembrane protein 255B

chr3_-_116712644 0.218 ENSMUST00000029569.2
 Slc35a3
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chrX_+_140367494 0.208 ENSMUST00000141660.1
 Frmpd3
FERM and PDZ domain containing 3
chr19_-_40402267 0.194 ENSMUST00000099467.3
ENSMUST00000099466.3
ENSMUST00000165212.1
ENSMUST00000165469.1
 Sorbs1



sorbin and SH3 domain containing 1



chr7_+_51880312 0.194 ENSMUST00000145049.1
 Gas2
growth arrest specific 2
chr15_-_43869993 0.187 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr19_-_6925367 0.179 ENSMUST00000057716.4
 Tex40
testis expressed 40
chr13_+_93304799 0.163 ENSMUST00000080127.5
 Homer1
homer homolog 1 (Drosophila)
chr4_+_15881255 0.135 ENSMUST00000029876.1
 Calb1
calbindin 1
chr8_-_54724474 0.125 ENSMUST00000175915.1
 Wdr17
WD repeat domain 17
chr11_-_74724670 0.125 ENSMUST00000021091.8
 Pafah1b1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chrX_-_143933204 0.124 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chr14_+_118137101 0.106 ENSMUST00000022728.2
 Gpr180
G protein-coupled receptor 180
chr10_+_72309225 0.105 ENSMUST00000061324.4
 Gm9923
predicted pseudogene 9923
chr5_+_88583527 0.084 ENSMUST00000031229.6
 Rufy3
RUN and FYVE domain containing 3
chr16_+_44347121 0.078 ENSMUST00000050897.6
 Spice1
spindle and centriole associated protein 1
chr8_-_105471481 0.065 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr3_+_94413244 0.060 ENSMUST00000166032.1
ENSMUST00000045245.5
 Tdrkh

tudor and KH domain containing protein

chr5_+_31526989 0.056 ENSMUST00000114533.2
ENSMUST00000117262.1
ENSMUST00000117319.1
 Slc4a1ap


solute carrier family 4 (anion exchanger), member 1, adaptor protein


chr13_+_93304066 0.054 ENSMUST00000109493.1
 Homer1
homer homolog 1 (Drosophila)
chr6_-_119388671 0.053 ENSMUST00000169744.1
 Adipor2
adiponectin receptor 2
chr8_+_110618577 0.032 ENSMUST00000034190.9
 Vac14
Vac14 homolog (S. cerevisiae)
chr13_-_85127514 0.031 ENSMUST00000179230.1
 Gm4076
predicted gene 4076
chr12_+_103388656 0.028 ENSMUST00000101094.2
ENSMUST00000021620.6
 Otub2

OTU domain, ubiquitin aldehyde binding 2

chrX_+_38600626 0.020 ENSMUST00000000365.2
 Mcts1
malignant T cell amplified sequence 1
chr6_+_49319274 0.015 ENSMUST00000055559.7
ENSMUST00000114491.1
 Ccdc126

coiled-coil domain containing 126

chr6_-_3494587 0.013 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chrX_-_101222426 0.012 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
 Snx12


sorting nexin 12


chr11_-_96977660 0.008 ENSMUST00000107626.1
ENSMUST00000107624.1
 Sp2

Sp2 transcription factor

chr13_-_21810190 0.006 ENSMUST00000110469.1
ENSMUST00000091749.2
 Hist1h2bq

histone cluster 1, H2bq


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.1 0.3 GO:2000393 negative regulation of lamellipodium morphogenesis(GO:2000393)
0.1 0.6 GO:0017121 phospholipid scrambling(GO:0017121)
0.1 1.4 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.2 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.0 0.3 GO:0060662 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.3 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.7 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661) regulation of microtubule motor activity(GO:2000574)
0.0 0.4 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0019236 response to pheromone(GO:0019236)
0.0 0.2 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.6 GO:0008347 glial cell migration(GO:0008347)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.7 GO:0008305 integrin complex(GO:0008305) protein complex involved in cell adhesion(GO:0098636)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0071437 invadopodium(GO:0071437)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.6 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.2 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.3 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0045505 dynein intermediate chain binding(GO:0045505)
0.0 0.4 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)