Motif ID: Hoxb7

Z-value: 4.283


Transcription factors associated with Hoxb7:

Gene SymbolEntrez IDGene Name
Hoxb7 ENSMUSG00000038721.8 Hoxb7



Activity profile for motif Hoxb7.

activity profile for motif Hoxb7


Sorted Z-values histogram for motif Hoxb7

Sorted Z-values for motif Hoxb7



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb7

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_144209558 27.338 ENSMUST00000111749.1
ENSMUST00000170367.2
 Sox5

SRY-box containing gene 5

chr6_-_144209471 26.926 ENSMUST00000038815.7
 Sox5
SRY-box containing gene 5
chr6_-_144209448 26.451 ENSMUST00000077160.5
 Sox5
SRY-box containing gene 5
chr12_-_31713873 25.422 ENSMUST00000057783.4
ENSMUST00000174480.2
ENSMUST00000176710.1
 Gpr22


G protein-coupled receptor 22


chr14_-_12345847 24.520 ENSMUST00000022262.4
 Fezf2
Fez family zinc finger 2
chr4_+_102589687 22.905 ENSMUST00000097949.4
ENSMUST00000106901.1
 Pde4b

phosphodiesterase 4B, cAMP specific

chrX_-_43167817 21.533 ENSMUST00000115058.1
ENSMUST00000115059.1
 Tenm1

teneurin transmembrane protein 1

chr10_-_64090241 20.978 ENSMUST00000133588.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr10_-_64090265 19.855 ENSMUST00000105439.1
 Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr3_+_67892189 18.809 ENSMUST00000063263.3
 Iqcj
IQ motif containing J
chr18_-_13972617 15.504 ENSMUST00000025288.7
 Zfp521
zinc finger protein 521
chr14_+_75455957 15.408 ENSMUST00000164848.1
 Siah3
seven in absentia homolog 3 (Drosophila)
chr6_+_15196949 12.875 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
 Foxp2



forkhead box P2



chr1_+_34005872 11.985 ENSMUST00000182296.1
 Dst
dystonin
chr4_-_82850721 10.916 ENSMUST00000139401.1
 Zdhhc21
zinc finger, DHHC domain containing 21
chr6_+_96113146 10.894 ENSMUST00000122120.1
 Fam19a1
family with sequence similarity 19, member A1
chrX_-_43274786 10.730 ENSMUST00000016294.7
 Tenm1
teneurin transmembrane protein 1
chr8_-_109251698 10.600 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr6_+_15185456 10.436 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
 Foxp2



forkhead box P2



chr15_-_48791933 10.208 ENSMUST00000160658.1
ENSMUST00000100670.3
ENSMUST00000162830.1
 Csmd3


CUB and Sushi multiple domains 3



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 416 entries
Log-likelihood per target Total log-likelihoodTermDescription
9.8 78.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
4.1 53.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
1.2 48.0 GO:0006376 mRNA splice site selection(GO:0006376)
2.7 40.2 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.5 40.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
1.4 34.1 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
2.9 32.1 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
2.5 27.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.2 24.9 GO:0008090 retrograde axonal transport(GO:0008090)
0.3 24.2 GO:0001578 microtubule bundle formation(GO:0001578)
3.6 21.5 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
2.3 21.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
1.6 21.1 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
3.5 20.7 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
2.1 16.9 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
1.4 16.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.3 16.6 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.6 16.2 GO:0060074 synapse maturation(GO:0060074)
3.2 16.0 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
1.8 15.9 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 189 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 149.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.4 57.1 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.1 45.4 GO:0005887 integral component of plasma membrane(GO:0005887)
1.8 41.7 GO:0000930 gamma-tubulin complex(GO:0000930)
1.0 36.3 GO:0032809 neuronal cell body membrane(GO:0032809)
0.2 28.0 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
1.3 26.9 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
6.0 23.8 GO:0031673 H zone(GO:0031673)
0.3 21.7 GO:0097060 synaptic membrane(GO:0097060)
1.2 20.2 GO:0031430 M band(GO:0031430)
2.2 19.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
1.6 17.6 GO:0043083 synaptic cleft(GO:0043083)
0.8 15.9 GO:0071564 npBAF complex(GO:0071564)
1.0 15.4 GO:0031045 dense core granule(GO:0031045)
4.9 14.7 GO:0043512 inhibin A complex(GO:0043512)
0.4 14.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.5 14.4 GO:0097440 apical dendrite(GO:0097440)
0.0 13.4 GO:0005794 Golgi apparatus(GO:0005794)
0.8 12.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
4.1 12.4 GO:0032437 cuticular plate(GO:0032437)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 231 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 99.8 GO:0046982 protein heterodimerization activity(GO:0046982)
1.5 71.7 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.6 63.8 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.1 63.0 GO:0044822 poly(A) RNA binding(GO:0044822)
1.6 48.5 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.8 35.5 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.2 33.1 GO:0042393 histone binding(GO:0042393)
0.1 28.4 GO:0008017 microtubule binding(GO:0008017)
0.2 27.7 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
3.2 25.8 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.5 24.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.5 23.4 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.9 19.6 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.1 16.6 GO:0005057 receptor signaling protein activity(GO:0005057)
2.7 16.0 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 16.0 GO:0000287 magnesium ion binding(GO:0000287)
0.6 15.8 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.5 15.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.9 14.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.8 14.3 GO:0005540 hyaluronic acid binding(GO:0005540)