Motif ID: Hoxc10

Z-value: 0.791


Transcription factors associated with Hoxc10:

Gene SymbolEntrez IDGene Name
Hoxc10 ENSMUSG00000022484.7 Hoxc10



Activity profile for motif Hoxc10.

activity profile for motif Hoxc10


Sorted Z-values histogram for motif Hoxc10

Sorted Z-values for motif Hoxc10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc10

PNG image of the network

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Top targets:


Showing 1 to 20 of 92 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_25469742 4.726 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr2_-_25470031 4.002 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chrX_+_169685191 2.134 ENSMUST00000112104.1
ENSMUST00000112107.1
 Mid1

midline 1

chr2_+_73271925 1.827 ENSMUST00000090813.5
 Sp9
trans-acting transcription factor 9
chr10_-_49783259 1.826 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
 Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr3_-_63851251 1.726 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
 Plch1


phospholipase C, eta 1


chr6_-_136875794 1.696 ENSMUST00000032342.1
 Mgp
matrix Gla protein
chr4_+_144893127 1.666 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr14_+_13454010 1.428 ENSMUST00000112656.2
 Synpr
synaptoporin
chr18_-_15063560 1.391 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chr11_-_79504078 1.330 ENSMUST00000164465.2
 Omg
oligodendrocyte myelin glycoprotein
chr3_+_31902666 1.321 ENSMUST00000119970.1
ENSMUST00000178668.1
 Kcnmb2

potassium large conductance calcium-activated channel, subfamily M, beta member 2

chrM_+_3906 1.177 ENSMUST00000082396.1
 mt-Nd2
mitochondrially encoded NADH dehydrogenase 2
chr13_-_84064772 1.173 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr5_-_62766153 1.108 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_+_81936911 1.030 ENSMUST00000135663.1
 Csdc2
cold shock domain containing C2, RNA binding
chr5_+_71699918 0.985 ENSMUST00000031122.7
 Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr15_+_81936753 0.950 ENSMUST00000038757.7
 Csdc2
cold shock domain containing C2, RNA binding
chr13_-_91388079 0.876 ENSMUST00000181054.1
 A830009L08Rik
RIKEN cDNA A830009L08 gene
chr5_-_111761697 0.845 ENSMUST00000129146.1
ENSMUST00000137398.1
ENSMUST00000129065.1
 E130006D01Rik


RIKEN cDNA E130006D01 gene



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 8.7 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 1.8 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 1.8 GO:0030326 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.2 1.7 GO:0042572 retinol metabolic process(GO:0042572)
0.0 1.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 1.7 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 1.7 GO:0048015 phosphatidylinositol-mediated signaling(GO:0048015)
0.2 1.3 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.3 GO:0032291 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.1 1.2 GO:0010388 cullin deneddylation(GO:0010388)
0.1 1.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 1.0 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.8 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.1 0.8 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 0.7 GO:0048014 Tie signaling pathway(GO:0048014)
0.1 0.7 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 0.7 GO:0035904 aorta development(GO:0035904)
0.2 0.6 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.6 GO:0003430 tolerance induction to self antigen(GO:0002513) growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.6 GO:2001222 regulation of neuron migration(GO:2001222)

Gene overrepresentation in cellular_component category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 1.8 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 1.3 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.2 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.1 GO:0070469 respiratory chain(GO:0070469)
0.1 1.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 1.0 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.2 0.8 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.7 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.7 GO:0042734 presynaptic membrane(GO:0042734)
0.1 0.5 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.5 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 0.4 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.3 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.0 0.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 27 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 8.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 2.1 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 1.8 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.2 1.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 1.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.1 1.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 1.2 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.1 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 1.0 GO:0050811 GABA receptor binding(GO:0050811)
0.2 0.8 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.1 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.7 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.7 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.2 0.6 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.6 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.5 GO:0038132 neuregulin binding(GO:0038132)
0.1 0.5 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)