Motif ID: Hoxc13_Hoxd13

Z-value: 1.009




Activity profile for motif Hoxc13_Hoxd13.

activity profile for motif Hoxc13_Hoxd13


Sorted Z-values histogram for motif Hoxc13_Hoxd13

Sorted Z-values for motif Hoxc13_Hoxd13



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc13_Hoxd13

PNG image of the network

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Top targets:


Showing 1 to 20 of 89 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_16014457 4.212 ENSMUST00000164993.1
 Inhba
inhibin beta-A
chr4_+_54945038 3.324 ENSMUST00000133895.1
 Zfp462
zinc finger protein 462
chr7_-_73537621 3.198 ENSMUST00000172704.1
 Chd2
chromodomain helicase DNA binding protein 2
chr3_-_142169196 2.787 ENSMUST00000098568.1
 Bmpr1b
bone morphogenetic protein receptor, type 1B
chr3_-_142169311 2.610 ENSMUST00000106230.1
 Bmpr1b
bone morphogenetic protein receptor, type 1B
chr6_+_108213086 2.493 ENSMUST00000032192.6
 Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr16_-_74411776 1.634 ENSMUST00000116586.2
 Robo2
roundabout homolog 2 (Drosophila)
chr19_-_7341848 1.489 ENSMUST00000171393.1
 Mark2
MAP/microtubule affinity-regulating kinase 2
chr18_-_38209762 1.484 ENSMUST00000057185.6
 Pcdh1
protocadherin 1
chr11_+_77216180 1.194 ENSMUST00000037912.5
ENSMUST00000156488.1
 Ssh2

slingshot homolog 2 (Drosophila)

chr4_-_133602168 1.072 ENSMUST00000057311.3
 Sfn
stratifin
chr6_+_96115249 1.026 ENSMUST00000075080.5
 Fam19a1
family with sequence similarity 19, member A1
chr8_+_34807287 0.945 ENSMUST00000033930.4
 Dusp4
dual specificity phosphatase 4
chr1_-_56978534 0.937 ENSMUST00000177282.1
 Satb2
special AT-rich sequence binding protein 2
chr1_-_156939387 0.870 ENSMUST00000171292.1
 Ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr17_-_13761441 0.851 ENSMUST00000127032.1
 Tcte2
t-complex-associated testis expressed 2
chr5_-_66514815 0.844 ENSMUST00000161879.1
ENSMUST00000159357.1
 Apbb2

amyloid beta (A4) precursor protein-binding, family B, member 2

chr16_+_23226014 0.824 ENSMUST00000178797.1
 St6gal1
beta galactoside alpha 2,6 sialyltransferase 1
chr17_-_6477102 0.753 ENSMUST00000167717.2
 Tmem181b-ps
transmembrane protein 181B, pseudogene
chr11_-_95699143 0.724 ENSMUST00000062249.2
 Gm9796
predicted gene 9796

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 5.4 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.8 4.2 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
0.1 3.3 GO:0043392 negative regulation of DNA binding(GO:0043392)
0.2 3.2 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.4 2.5 GO:0042045 epithelial fluid transport(GO:0042045)
0.5 1.6 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 1.5 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 1.5 GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197)
0.1 1.4 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 1.2 GO:0010591 regulation of lamellipodium assembly(GO:0010591)
0.1 1.1 GO:0031424 keratinization(GO:0031424)
0.3 1.0 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.2 0.9 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.1 0.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 0.8 GO:1990743 protein sialylation(GO:1990743)
0.0 0.8 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.7 GO:0009303 rRNA transcription(GO:0009303)
0.0 0.7 GO:0006378 mRNA polyadenylation(GO:0006378)
0.2 0.6 GO:0009405 pathogenesis(GO:0009405)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.4 4.2 GO:0043512 inhibin A complex(GO:0043512)
0.8 2.5 GO:0031088 platelet dense granule membrane(GO:0031088)
0.0 1.7 GO:0016605 PML body(GO:0016605)
0.0 1.6 GO:0030673 axolemma(GO:0030673)
0.3 1.5 GO:0097427 microtubule bundle(GO:0097427)
0.1 1.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.7 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.0 0.5 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.5 GO:0005916 fascia adherens(GO:0005916)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 0.0 GO:0032040 small-subunit processome(GO:0032040)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 5.4 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.7 4.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 3.2 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.8 2.5 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 1.7 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.2 1.6 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.5 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.2 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.1 GO:0051219 phosphoprotein binding(GO:0051219)
0.1 1.0 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.9 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 0.7 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.7 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 0.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 0.6 GO:0050815 phosphoserine binding(GO:0050815)
0.1 0.6 GO:0015643 toxic substance binding(GO:0015643)