Motif ID: Hoxc6

Z-value: 0.433


Transcription factors associated with Hoxc6:

Gene SymbolEntrez IDGene Name
Hoxc6 ENSMUSG00000001661.4 Hoxc6



Activity profile for motif Hoxc6.

activity profile for motif Hoxc6


Sorted Z-values histogram for motif Hoxc6

Sorted Z-values for motif Hoxc6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc6

PNG image of the network

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Top targets:


Showing 1 to 20 of 51 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_17574268 1.804 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr3_+_5218546 1.012 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr11_-_26210553 0.920 ENSMUST00000101447.3
 5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr3_+_151437887 0.849 ENSMUST00000046977.7
 Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr4_+_144893127 0.755 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr19_+_11518493 0.709 ENSMUST00000025580.3
 Ms4a6b
membrane-spanning 4-domains, subfamily A, member 6B
chr11_-_109472611 0.651 ENSMUST00000168740.1
 Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr3_+_5218516 0.613 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr3_-_113574242 0.560 ENSMUST00000142505.2
 Amy1
amylase 1, salivary
chr10_-_53647080 0.534 ENSMUST00000169866.1
 Fam184a
family with sequence similarity 184, member A
chr19_+_11469353 0.483 ENSMUST00000165310.1
 Ms4a6c
membrane-spanning 4-domains, subfamily A, member 6C
chr3_+_66985680 0.367 ENSMUST00000065047.6
 Rsrc1
arginine/serine-rich coiled-coil 1
chr10_-_100589205 0.351 ENSMUST00000054471.8
 4930430F08Rik
RIKEN cDNA 4930430F08 gene
chrM_-_14060 0.348 ENSMUST00000082419.1
 mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr6_-_65144908 0.312 ENSMUST00000031982.4
 Hpgds
hematopoietic prostaglandin D synthase
chrM_+_14138 0.305 ENSMUST00000082421.1
 mt-Cytb
mitochondrially encoded cytochrome b
chr10_+_5593718 0.298 ENSMUST00000051809.8
 Myct1
myc target 1
chr3_+_5218589 0.282 ENSMUST00000177488.1
 Zfhx4
zinc finger homeodomain 4
chrM_+_9452 0.272 ENSMUST00000082411.1
 mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr9_-_21760275 0.271 ENSMUST00000098942.4
 Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.8 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.8 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.8 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.7 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.3 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.3 GO:0033762 response to glucagon(GO:0033762)
0.1 0.2 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035)
0.1 0.2 GO:0009812 flavonoid metabolic process(GO:0009812) flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696)
0.1 0.2 GO:0097274 urea homeostasis(GO:0097274)
0.1 0.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)

Gene overrepresentation in cellular_component category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0045275 respiratory chain complex III(GO:0045275)
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)

Gene overrepresentation in molecular_function category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.2 0.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 0.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.3 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)