Motif ID: Hoxc6

Z-value: 0.433


Transcription factors associated with Hoxc6:

Gene SymbolEntrez IDGene Name
Hoxc6 ENSMUSG00000001661.4 Hoxc6



Activity profile for motif Hoxc6.

activity profile for motif Hoxc6


Sorted Z-values histogram for motif Hoxc6

Sorted Z-values for motif Hoxc6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc6

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_17574268 1.804 ENSMUST00000030568.7
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr3_+_5218546 1.012 ENSMUST00000026284.6
Zfhx4
zinc finger homeodomain 4
chr11_-_26210553 0.920 ENSMUST00000101447.3
5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr3_+_151437887 0.849 ENSMUST00000046977.7
Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr4_+_144893127 0.755 ENSMUST00000142808.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr19_+_11518493 0.709 ENSMUST00000025580.3
Ms4a6b
membrane-spanning 4-domains, subfamily A, member 6B
chr11_-_109472611 0.651 ENSMUST00000168740.1
Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr3_+_5218516 0.613 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr3_-_113574242 0.560 ENSMUST00000142505.2
Amy1
amylase 1, salivary
chr10_-_53647080 0.534 ENSMUST00000169866.1
Fam184a
family with sequence similarity 184, member A
chr19_+_11469353 0.483 ENSMUST00000165310.1
Ms4a6c
membrane-spanning 4-domains, subfamily A, member 6C
chr3_+_66985680 0.367 ENSMUST00000065047.6
Rsrc1
arginine/serine-rich coiled-coil 1
chr10_-_100589205 0.351 ENSMUST00000054471.8
4930430F08Rik
RIKEN cDNA 4930430F08 gene
chrM_-_14060 0.348 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr6_-_65144908 0.312 ENSMUST00000031982.4
Hpgds
hematopoietic prostaglandin D synthase
chrM_+_14138 0.305 ENSMUST00000082421.1
mt-Cytb
mitochondrially encoded cytochrome b
chr10_+_5593718 0.298 ENSMUST00000051809.8
Myct1
myc target 1
chr3_+_5218589 0.282 ENSMUST00000177488.1
Zfhx4
zinc finger homeodomain 4
chrM_+_9452 0.272 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr9_-_21760275 0.271 ENSMUST00000098942.4
Spc24
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr3_+_66985700 0.256 ENSMUST00000046542.6
ENSMUST00000162693.1
Rsrc1

arginine/serine-rich coiled-coil 1

chr3_+_136670076 0.252 ENSMUST00000070198.7
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr7_-_19604444 0.250 ENSMUST00000086041.5
Clasrp
CLK4-associating serine/arginine rich protein
chr19_+_32619997 0.248 ENSMUST00000025833.6
Papss2
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr10_-_70655934 0.224 ENSMUST00000162144.1
ENSMUST00000162793.1
Phyhipl

phytanoyl-CoA hydroxylase interacting protein-like

chr1_+_19208914 0.222 ENSMUST00000027059.4
Tfap2b
transcription factor AP-2 beta
chr1_-_189922338 0.221 ENSMUST00000027897.7
Smyd2
SET and MYND domain containing 2
chr3_+_66985647 0.216 ENSMUST00000162362.1
ENSMUST00000065074.7
Rsrc1

arginine/serine-rich coiled-coil 1

chr1_-_22315792 0.202 ENSMUST00000164877.1
Rims1
regulating synaptic membrane exocytosis 1
chr18_+_37484955 0.188 ENSMUST00000053856.4
Pcdhb17
protocadherin beta 17
chr1_-_191907527 0.181 ENSMUST00000069573.5
1700034H15Rik
RIKEN cDNA 1700034H15 gene
chr7_+_5020376 0.179 ENSMUST00000076251.4
Zfp865
zinc finger protein 865
chr10_-_37138863 0.154 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr19_+_26748268 0.145 ENSMUST00000175791.1
ENSMUST00000176698.1
ENSMUST00000177252.1
ENSMUST00000176475.1
ENSMUST00000112637.2
Smarca2




SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2




chr15_-_50889691 0.143 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr7_+_73740277 0.139 ENSMUST00000107456.2
Fam174b
family with sequence similarity 174, member B
chr7_+_123123870 0.131 ENSMUST00000094053.5
Tnrc6a
trinucleotide repeat containing 6a
chr4_+_132351768 0.123 ENSMUST00000172202.1
Gm17300
predicted gene, 17300
chr16_-_21995478 0.119 ENSMUST00000074230.4
ENSMUST00000060673.6
Liph

lipase, member H

chr1_+_88134786 0.118 ENSMUST00000113134.1
ENSMUST00000140092.1
Ugt1a6a

UDP glucuronosyltransferase 1 family, polypeptide A6A

chr1_+_88103229 0.106 ENSMUST00000113135.3
ENSMUST00000113138.1
Ugt1a6a
Ugt1a6b
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr10_+_78393298 0.096 ENSMUST00000072739.4
Gm10146
predicted gene 10146
chr17_-_35115428 0.094 ENSMUST00000172854.1
ENSMUST00000062657.4
Ly6g5b

lymphocyte antigen 6 complex, locus G5B

chr6_-_3494587 0.052 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr7_-_16285454 0.051 ENSMUST00000174270.1
Ccdc9
coiled-coil domain containing 9
chr1_-_43827751 0.034 ENSMUST00000128261.1
ENSMUST00000126008.1
ENSMUST00000139451.1
Uxs1


UDP-glucuronate decarboxylase 1


chr7_-_24299310 0.027 ENSMUST00000145131.1
Zfp61
zinc finger protein 61
chr6_+_128399881 0.022 ENSMUST00000120405.1
Nrip2
nuclear receptor interacting protein 2
chr3_+_129213920 0.012 ENSMUST00000042587.10
Pitx2
paired-like homeodomain transcription factor 2
chr15_+_44619551 0.002 ENSMUST00000022964.7
Ebag9
estrogen receptor-binding fragment-associated gene 9
chr2_-_174346712 0.000 ENSMUST00000168292.1
Gm20721
predicted gene, 20721

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 0.3 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 0.2 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035)
0.1 0.2 GO:0009812 flavonoid metabolic process(GO:0009812) flavonoid biosynthetic process(GO:0009813) flavonoid glucuronidation(GO:0052696)
0.1 0.2 GO:0097274 urea homeostasis(GO:0097274)
0.1 0.8 GO:0042572 retinol metabolic process(GO:0042572)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.3 GO:0033762 response to glucagon(GO:0033762)
0.1 0.2 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.7 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.8 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.3 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.2 1.8 GO:0038191 neuropilin binding(GO:0038191)
0.1 0.8 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.3 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0004779 sulfate adenylyltransferase activity(GO:0004779)
0.0 0.6 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)