Motif ID: Hoxc9

Z-value: 0.579


Transcription factors associated with Hoxc9:

Gene SymbolEntrez IDGene Name
Hoxc9 ENSMUSG00000036139.6 Hoxc9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hoxc9mm10_v2_chr15_+_102977032_102977032-0.234.2e-01Click!


Activity profile for motif Hoxc9.

activity profile for motif Hoxc9


Sorted Z-values histogram for motif Hoxc9

Sorted Z-values for motif Hoxc9



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc9

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_+_118283719 2.622 ENSMUST00000117160.1
Cdh13
cadherin 13
chr6_-_99044414 2.550 ENSMUST00000177507.1
ENSMUST00000123992.1
Foxp1

forkhead box P1

chr3_+_67892189 2.459 ENSMUST00000063263.3
Iqcj
IQ motif containing J
chr15_-_48791933 0.823 ENSMUST00000160658.1
ENSMUST00000100670.3
ENSMUST00000162830.1
Csmd3


CUB and Sushi multiple domains 3


chr18_+_65582281 0.706 ENSMUST00000183319.1
Zfp532
zinc finger protein 532
chr19_+_24875679 0.673 ENSMUST00000073080.5
Gm10053
predicted gene 10053
chrX_-_143933089 0.661 ENSMUST00000087313.3
Dcx
doublecortin
chr1_+_66321708 0.651 ENSMUST00000114013.1
Map2
microtubule-associated protein 2
chr4_+_100776664 0.626 ENSMUST00000030257.8
ENSMUST00000097955.2
Cachd1

cache domain containing 1

chr13_-_25270076 0.613 ENSMUST00000057866.6
Nrsn1
neurensin 1
chr18_+_65582239 0.591 ENSMUST00000182684.1
Zfp532
zinc finger protein 532
chr7_-_30612731 0.575 ENSMUST00000006476.4
Upk1a
uroplakin 1A
chr18_-_56975333 0.554 ENSMUST00000139243.2
ENSMUST00000025488.8
C330018D20Rik

RIKEN cDNA C330018D20 gene

chrX_+_56609751 0.545 ENSMUST00000144068.1
Slc9a6
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chrX_-_105928547 0.502 ENSMUST00000101305.2
Atrx
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr8_-_120228221 0.496 ENSMUST00000183235.1
A330074K22Rik
RIKEN cDNA A330074K22 gene
chr12_-_15816762 0.470 ENSMUST00000020922.7
Trib2
tribbles homolog 2 (Drosophila)
chr9_+_53771499 0.458 ENSMUST00000048670.8
Slc35f2
solute carrier family 35, member F2
chr1_+_187997821 0.451 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr5_+_67260696 0.442 ENSMUST00000161233.1
ENSMUST00000160352.1
Tmem33

transmembrane protein 33

chr1_+_187997835 0.425 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr9_+_35423582 0.402 ENSMUST00000154652.1
Cdon
cell adhesion molecule-related/down-regulated by oncogenes
chr11_-_72215592 0.339 ENSMUST00000021157.8
Med31
mediator of RNA polymerase II transcription, subunit 31 homolog (yeast)
chr6_+_54269135 0.336 ENSMUST00000114401.1
Chn2
chimerin (chimaerin) 2
chrX_-_141474034 0.326 ENSMUST00000101205.2
Col4a6
collagen, type IV, alpha 6
chr4_-_150003130 0.302 ENSMUST00000084117.6
H6pd
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr10_-_88605017 0.296 ENSMUST00000119185.1
ENSMUST00000121629.1
Mybpc1

myosin binding protein C, slow-type

chr11_+_85353156 0.293 ENSMUST00000108061.1
ENSMUST00000108062.1
ENSMUST00000108056.1
ENSMUST00000138423.1
ENSMUST00000074875.4
ENSMUST00000092821.3
Bcas3





breast carcinoma amplified sequence 3





chr2_-_84650714 0.275 ENSMUST00000111697.2
ENSMUST00000111670.2
ENSMUST00000111696.1
ENSMUST00000111678.1
ENSMUST00000111690.1
ENSMUST00000111695.1
ENSMUST00000111677.1
ENSMUST00000111698.1
ENSMUST00000099941.2
ENSMUST00000111676.1
ENSMUST00000111694.1
ENSMUST00000111675.1
ENSMUST00000111689.1
ENSMUST00000111687.1
ENSMUST00000111692.1
ENSMUST00000111685.1
ENSMUST00000111686.1
ENSMUST00000111688.1
ENSMUST00000111693.1
ENSMUST00000111684.1
Ctnnd1



















catenin (cadherin associated protein), delta 1



















chr2_-_84650490 0.254 ENSMUST00000066177.3
Ctnnd1
catenin (cadherin associated protein), delta 1
chr10_+_128411616 0.243 ENSMUST00000096386.5
ENSMUST00000171342.1
Rnf41

ring finger protein 41

chr19_-_10880370 0.224 ENSMUST00000133303.1
Tmem109
transmembrane protein 109
chr2_-_84650676 0.219 ENSMUST00000067232.3
Ctnnd1
catenin (cadherin associated protein), delta 1
chrX_-_143933204 0.216 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
Dcx


doublecortin


chr2_-_84650760 0.192 ENSMUST00000111691.1
Ctnnd1
catenin (cadherin associated protein), delta 1
chrX_+_56609843 0.173 ENSMUST00000077741.5
ENSMUST00000114784.2
Slc9a6

solute carrier family 9 (sodium/hydrogen exchanger), member 6

chr18_+_65582390 0.170 ENSMUST00000169679.1
ENSMUST00000183326.1
Zfp532

zinc finger protein 532

chr10_+_43524080 0.168 ENSMUST00000057649.6
Gm9803
predicted gene 9803
chr10_-_61979073 0.168 ENSMUST00000105453.1
ENSMUST00000105452.2
ENSMUST00000105454.2
Col13a1


collagen, type XIII, alpha 1


chr9_-_7835255 0.159 ENSMUST00000074246.6
Birc2
baculoviral IAP repeat-containing 2
chr5_+_67260565 0.154 ENSMUST00000037918.5
ENSMUST00000162543.1
Tmem33

transmembrane protein 33

chr5_-_67427794 0.147 ENSMUST00000169190.1
Bend4
BEN domain containing 4
chr5_-_44101668 0.145 ENSMUST00000087441.4
ENSMUST00000074113.6
Prom1

prominin 1

chr2_-_91255995 0.141 ENSMUST00000180732.1
Gm17281
predicted gene, 17281
chr12_-_8499985 0.136 ENSMUST00000067384.4
Rhob
ras homolog gene family, member B
chr10_-_92162753 0.128 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chrX_-_103186618 0.116 ENSMUST00000121720.1
Nap1l2
nucleosome assembly protein 1-like 2
chr9_+_121710389 0.109 ENSMUST00000035113.9
Deb1
differentially expressed in B16F10 1
chr1_+_85100164 0.065 ENSMUST00000097669.1
Gm10553
predicted gene 10553
chr8_+_54954728 0.062 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr1_+_11414089 0.053 ENSMUST00000048613.7
ENSMUST00000171690.2
ENSMUST00000137824.1
ENSMUST00000135014.1
ENSMUST00000179089.1
A830018L16Rik



A830018L16Rik
RIKEN cDNA A830018L16 gene



RIKEN cDNA A830018L16 gene
chr2_+_91082362 0.053 ENSMUST00000169852.1
Spi1
spleen focus forming virus (SFFV) proviral integration oncogene
chr10_+_4710119 0.048 ENSMUST00000105588.1
ENSMUST00000105589.1
Esr1

estrogen receptor 1 (alpha)

chr4_-_109202217 0.046 ENSMUST00000160774.1
ENSMUST00000030288.7
ENSMUST00000162787.2
Osbpl9


oxysterol binding protein-like 9


chr6_-_119388671 0.032 ENSMUST00000169744.1
Adipor2
adiponectin receptor 2
chr1_+_58210397 0.022 ENSMUST00000040442.5
Aox4
aldehyde oxidase 4
chr11_+_3330401 0.022 ENSMUST00000045153.4
Pik3ip1
phosphoinositide-3-kinase interacting protein 1
chr11_-_94242701 0.016 ENSMUST00000061469.3
Wfikkn2
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr3_+_129199919 0.015 ENSMUST00000029657.9
ENSMUST00000106382.4
Pitx2

paired-like homeodomain transcription factor 2

chr3_+_129199960 0.010 ENSMUST00000173645.2
Pitx2
paired-like homeodomain transcription factor 2
chr2_-_38714491 0.010 ENSMUST00000028084.4
Nr5a1
nuclear receptor subfamily 5, group A, member 1
chr10_+_69925954 0.008 ENSMUST00000181974.1
ENSMUST00000182795.1
ENSMUST00000182437.1
Ank3


ankyrin 3, epithelial


chr1_+_74284930 0.007 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
Pnkd


paroxysmal nonkinesiogenic dyskinesia


chr13_+_89540636 0.006 ENSMUST00000022108.7
Hapln1
hyaluronan and proteoglycan link protein 1
chr3_+_129199878 0.004 ENSMUST00000174661.2
Pitx2
paired-like homeodomain transcription factor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.6 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.3 2.6 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 0.6 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.2 0.9 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 0.5 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.1 0.7 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 0.2 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.1 0.4 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.9 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.0 0.5 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.2 GO:1901524 regulation of macromitophagy(GO:1901524) negative regulation of macromitophagy(GO:1901525)
0.0 0.3 GO:0038063 collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063)
0.0 0.3 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.0 0.1 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.3 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.0 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.1 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.1 0.7 GO:0044308 axonal spine(GO:0044308)
0.1 0.9 GO:0005915 zonula adherens(GO:0005915)
0.1 0.7 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 0.3 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.1 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.1 GO:0071914 prominosome(GO:0071914)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.7 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.3 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.1 0.3 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.1 0.7 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 0.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.5 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.9 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.9 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.5 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 2.6 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.8 GO:0045296 cadherin binding(GO:0045296)
0.0 0.0 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)