Motif ID: Hoxd10

Z-value: 0.439


Transcription factors associated with Hoxd10:

Gene SymbolEntrez IDGene Name
Hoxd10 ENSMUSG00000050368.3 Hoxd10



Activity profile for motif Hoxd10.

activity profile for motif Hoxd10


Sorted Z-values histogram for motif Hoxd10

Sorted Z-values for motif Hoxd10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd10

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_+_102254993 1.060 ENSMUST00000106908.2
Pde4b
phosphodiesterase 4B, cAMP specific
chr6_-_92481343 0.775 ENSMUST00000113445.1
Prickle2
prickle homolog 2 (Drosophila)
chr10_+_69534039 0.752 ENSMUST00000182557.1
Ank3
ankyrin 3, epithelial
chr17_-_78684262 0.696 ENSMUST00000145480.1
Strn
striatin, calmodulin binding protein
chr9_-_90255927 0.539 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr8_-_109251698 0.527 ENSMUST00000079189.3
4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr10_+_116177351 0.517 ENSMUST00000155606.1
ENSMUST00000128399.1
Ptprr

protein tyrosine phosphatase, receptor type, R

chr17_+_71204647 0.401 ENSMUST00000126681.1
Lpin2
lipin 2
chr15_-_103215285 0.383 ENSMUST00000122182.1
ENSMUST00000108813.3
ENSMUST00000127191.1
Cbx5


chromobox 5


chr7_+_96210107 0.367 ENSMUST00000138760.1
Tenm4
teneurin transmembrane protein 4
chr4_+_100478806 0.358 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
Ube2u


ubiquitin-conjugating enzyme E2U (putative)


chr2_+_65620829 0.336 ENSMUST00000028377.7
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr6_+_33249085 0.297 ENSMUST00000052266.8
ENSMUST00000090381.4
ENSMUST00000115080.1
Exoc4


exocyst complex component 4


chrX_+_66653003 0.296 ENSMUST00000036043.4
Slitrk2
SLIT and NTRK-like family, member 2
chr13_-_58354862 0.291 ENSMUST00000043605.5
Kif27
kinesin family member 27
chr7_+_30095150 0.290 ENSMUST00000130526.1
ENSMUST00000108200.1
Zfp260

zinc finger protein 260

chr3_+_55461758 0.282 ENSMUST00000070418.4
Dclk1
doublecortin-like kinase 1
chr9_+_27790947 0.268 ENSMUST00000115243.2
Opcml
opioid binding protein/cell adhesion molecule-like
chr14_-_87141114 0.250 ENSMUST00000168889.1
Diap3
diaphanous homolog 3 (Drosophila)
chr2_+_106693185 0.245 ENSMUST00000111063.1
Mpped2
metallophosphoesterase domain containing 2
chr9_+_104569671 0.236 ENSMUST00000057742.8
Cpne4
copine IV
chr5_+_121777929 0.213 ENSMUST00000160821.1
Atxn2
ataxin 2
chrX_-_70365052 0.209 ENSMUST00000101509.2
Ids
iduronate 2-sulfatase
chr15_+_9140527 0.206 ENSMUST00000090380.4
Lmbrd2
LMBR1 domain containing 2
chr3_-_95282076 0.178 ENSMUST00000015855.7
Prune
prune homolog (Drosophila)
chr4_+_43401232 0.147 ENSMUST00000125399.1
Rusc2
RUN and SH3 domain containing 2
chr3_+_85915722 0.139 ENSMUST00000054148.7
Gm9790
predicted gene 9790
chr13_+_40917626 0.136 ENSMUST00000067778.6
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr2_+_120404757 0.121 ENSMUST00000135074.1
Ganc
glucosidase, alpha; neutral C
chr14_-_93888732 0.105 ENSMUST00000068992.2
Pcdh9
protocadherin 9
chr4_-_36136463 0.102 ENSMUST00000098151.2
Lingo2
leucine rich repeat and Ig domain containing 2
chr12_+_55089202 0.076 ENSMUST00000021407.10
Srp54a
signal recognition particle 54A
chr15_-_93336800 0.073 ENSMUST00000080299.6
Yaf2
YY1 associated factor 2
chr5_-_92328068 0.072 ENSMUST00000113093.3
Cxcl9
chemokine (C-X-C motif) ligand 9
chr1_-_152625212 0.061 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr4_-_108833544 0.061 ENSMUST00000102740.1
ENSMUST00000102741.1
Btf3l4

basic transcription factor 3-like 4

chr7_-_73541738 0.050 ENSMUST00000169922.2
Chd2
chromodomain helicase DNA binding protein 2
chr11_-_110168073 0.046 ENSMUST00000044850.3
Abca9
ATP-binding cassette, sub-family A (ABC1), member 9
chrX_-_74246534 0.044 ENSMUST00000101454.2
ENSMUST00000033699.6
Flna

filamin, alpha

chr1_-_45503282 0.036 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr14_+_79515618 0.017 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr18_-_75697639 0.017 ENSMUST00000165559.1
Ctif
CBP80/20-dependent translation initiation factor
chr9_-_45828618 0.011 ENSMUST00000117194.1
Cep164
centrosomal protein 164
chr6_+_97807014 0.007 ENSMUST00000043637.7
Mitf
microphthalmia-associated transcription factor
chr9_+_95857597 0.002 ENSMUST00000034980.7
Atr
ataxia telangiectasia and Rad3 related

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.1 0.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.4 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.1 0.3 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.1 1.1 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.8 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.3 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.0 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.4 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.2 GO:0010603 regulation of cytoplasmic mRNA processing body assembly(GO:0010603)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0033503 HULC complex(GO:0033503)
0.0 1.1 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 1.1 GO:0033270 paranode region of axon(GO:0033270)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.0 0.4 GO:0010369 chromocenter(GO:0010369)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.2 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.0 0.1 GO:0004558 alpha-1,4-glucosidase activity(GO:0004558)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 1.1 GO:0030552 cAMP binding(GO:0030552)
0.0 0.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.7 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.2 GO:0050692 DBD domain binding(GO:0050692)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)