Motif ID: Hoxd12

Z-value: 1.524


Transcription factors associated with Hoxd12:

Gene SymbolEntrez IDGene Name
Hoxd12 ENSMUSG00000001823.4 Hoxd12



Activity profile for motif Hoxd12.

activity profile for motif Hoxd12


Sorted Z-values histogram for motif Hoxd12

Sorted Z-values for motif Hoxd12



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd12

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 123 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_144892813 6.163 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr16_+_42907563 5.864 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr4_+_144893127 5.797 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr4_-_154636831 5.493 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
 Prdm16






PR domain containing 16






chr4_+_144893077 5.060 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr13_-_84064772 4.827 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr2_-_114013619 4.383 ENSMUST00000090275.4
 Gjd2
gap junction protein, delta 2
chr6_+_125215551 3.575 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
 Vamp1


vesicle-associated membrane protein 1


chr19_+_53529100 3.522 ENSMUST00000038287.6
 Dusp5
dual specificity phosphatase 5
chr2_+_73271925 3.334 ENSMUST00000090813.5
 Sp9
trans-acting transcription factor 9
chr5_-_62766153 3.235 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_-_77347787 3.183 ENSMUST00000184848.1
ENSMUST00000184415.1
 Mlip

muscular LMNA-interacting protein

chr9_-_77347816 3.117 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
 Mlip



muscular LMNA-interacting protein



chr13_-_23622502 3.095 ENSMUST00000062045.2
 Hist1h1e
histone cluster 1, H1e
chr9_-_77347889 2.858 ENSMUST00000185039.1
 Mlip
muscular LMNA-interacting protein
chr18_-_15063560 2.772 ENSMUST00000168989.1
 Kctd1
potassium channel tetramerisation domain containing 1
chr15_+_81936753 2.677 ENSMUST00000038757.7
 Csdc2
cold shock domain containing C2, RNA binding
chr13_-_97747373 2.674 ENSMUST00000123535.1
 5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr15_+_81936911 2.475 ENSMUST00000135663.1
 Csdc2
cold shock domain containing C2, RNA binding
chr8_+_69902178 2.422 ENSMUST00000050373.5
 Tssk6
testis-specific serine kinase 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 17.0 GO:0042572 retinol metabolic process(GO:0042572)
0.4 9.2 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
1.2 5.9 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.2 5.9 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.8 5.5 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.9 3.7 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.2 3.6 GO:0035493 SNARE complex assembly(GO:0035493)
0.1 3.5 GO:0001706 endoderm formation(GO:0001706)
0.2 3.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.4 3.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 2.9 GO:0007601 visual perception(GO:0007601)
0.0 2.7 GO:0030326 embryonic limb morphogenesis(GO:0030326) embryonic appendage morphogenesis(GO:0035113)
0.3 2.4 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 2.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.7 2.2 GO:0036292 DNA rewinding(GO:0036292)
0.1 2.1 GO:0006828 manganese ion transport(GO:0006828)
0.1 2.1 GO:0046677 response to antibiotic(GO:0046677)
0.3 1.9 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.2 1.7 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) positive regulation of proteoglycan biosynthetic process(GO:1902730)
0.1 1.7 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.1 GO:0016605 PML body(GO:0016605)
0.1 8.0 GO:0016607 nuclear speck(GO:0016607)
0.1 5.5 GO:0017053 transcriptional repressor complex(GO:0017053)
0.3 4.4 GO:0005922 connexon complex(GO:0005922)
0.2 3.7 GO:0043205 fibril(GO:0043205)
0.7 3.6 GO:0070820 tertiary granule(GO:0070820)
0.1 3.4 GO:0005801 cis-Golgi network(GO:0005801)
0.3 3.0 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 2.8 GO:0000786 nucleosome(GO:0000786)
0.0 2.6 GO:0070469 respiratory chain(GO:0070469)
0.0 2.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.2 GO:0043596 nuclear replication fork(GO:0043596)
0.3 1.6 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 1.5 GO:0030057 desmosome(GO:0030057)
0.5 1.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.1 1.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.4 1.1 GO:0072534 perineuronal net(GO:0072534)
0.0 1.1 GO:0042734 presynaptic membrane(GO:0042734)
0.0 1.1 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.2 1.0 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.4 17.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 6.9 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.3 5.9 GO:0032183 SUMO binding(GO:0032183)
0.1 5.9 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 4.2 GO:0008134 transcription factor binding(GO:0008134)
0.7 3.7 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 3.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 3.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.1 3.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 3.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 2.8 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 2.8 GO:0003714 transcription corepressor activity(GO:0003714)
0.1 2.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.4 GO:0000287 magnesium ion binding(GO:0000287)
0.2 2.2 GO:0036310 annealing helicase activity(GO:0036310)
0.2 2.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.3 1.7 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 1.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.6 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 1.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)