Motif ID: Hoxd8

Z-value: 0.441


Transcription factors associated with Hoxd8:

Gene SymbolEntrez IDGene Name
Hoxd8 ENSMUSG00000027102.4 Hoxd8



Activity profile for motif Hoxd8.

activity profile for motif Hoxd8


Sorted Z-values histogram for motif Hoxd8

Sorted Z-values for motif Hoxd8



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd8

PNG image of the network

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Top targets:


Showing 1 to 20 of 85 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_48432723 0.599 ENSMUST00000046549.3
 Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr1_-_158814469 0.383 ENSMUST00000161589.2
 Pappa2
pappalysin 2
chr6_+_34384218 0.371 ENSMUST00000038383.7
ENSMUST00000115051.1
 Akr1b10

aldo-keto reductase family 1, member B10 (aldose reductase)

chr1_+_9547948 0.360 ENSMUST00000144177.1
 Adhfe1
alcohol dehydrogenase, iron containing, 1
chr12_-_90969768 0.355 ENSMUST00000181184.1
 4930544I03Rik
RIKEN cDNA 4930544I03 gene
chr9_+_80165013 0.338 ENSMUST00000035889.8
ENSMUST00000113268.1
 Myo6

myosin VI

chr3_-_19264959 0.335 ENSMUST00000121951.1
 Pde7a
phosphodiesterase 7A
chr4_+_101986626 0.298 ENSMUST00000106914.1
 Gm12789
predicted gene 12789
chr4_+_118961578 0.298 ENSMUST00000058651.4
 Lao1
L-amino acid oxidase 1
chr8_+_34054622 0.293 ENSMUST00000149618.1
 Gm9951
predicted gene 9951
chr3_+_127633134 0.288 ENSMUST00000029587.7
 Neurog2
neurogenin 2
chr13_-_85127514 0.275 ENSMUST00000179230.1
 Gm4076
predicted gene 4076
chr1_-_172027269 0.266 ENSMUST00000027837.6
ENSMUST00000111264.1
 Vangl2

vang-like 2 (van gogh, Drosophila)

chr3_+_76075583 0.258 ENSMUST00000160261.1
 Fstl5
follistatin-like 5
chr14_+_55559993 0.231 ENSMUST00000117236.1
 Dcaf11
DDB1 and CUL4 associated factor 11
chr6_+_71282280 0.213 ENSMUST00000080949.7
 Krcc1
lysine-rich coiled-coil 1
chr5_-_73191848 0.208 ENSMUST00000176910.1
 Fryl
furry homolog-like (Drosophila)
chr11_+_109543694 0.201 ENSMUST00000106696.1
 Arsg
arylsulfatase G
chr1_-_138848576 0.186 ENSMUST00000112030.2
 Lhx9
LIM homeobox protein 9
chr5_+_48372363 0.163 ENSMUST00000030968.2
 Pacrgl
PARK2 co-regulated-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 20 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.6 GO:0016556 mRNA modification(GO:0016556)
0.0 0.5 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.3 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.0 0.2 GO:0035262 gonad morphogenesis(GO:0035262)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.1 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0032911 nerve growth factor production(GO:0032902) negative regulation of transforming growth factor beta1 production(GO:0032911)
0.0 0.1 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.1 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.0 0.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0046549 retinal cone cell development(GO:0046549)
0.0 0.1 GO:0072539 T-helper 17 cell differentiation(GO:0072539)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.1 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)

Gene overrepresentation in cellular_component category:

Showing 1 to 5 of 5 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)

Gene overrepresentation in molecular_function category:

Showing 1 to 12 of 12 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.5 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.1 0.4 GO:0052650 retinal binding(GO:0016918) NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.3 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.2 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.2 GO:0004889 acetylcholine-activated cation-selective channel activity(GO:0004889)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.1 GO:0008502 melatonin receptor activity(GO:0008502)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0071862 protein phosphatase type 1 activator activity(GO:0071862)
0.0 0.1 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0048406 nerve growth factor binding(GO:0048406)