Motif ID: Hsf2

Z-value: 1.476


Transcription factors associated with Hsf2:

Gene SymbolEntrez IDGene Name
Hsf2 ENSMUSG00000019878.7 Hsf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hsf2mm10_v2_chr10_+_57486354_57486414-0.332.5e-01Click!


Activity profile for motif Hsf2.

activity profile for motif Hsf2


Sorted Z-values histogram for motif Hsf2

Sorted Z-values for motif Hsf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_17574268 5.732 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_+_17574726 5.129 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr13_-_37049203 4.087 ENSMUST00000037491.8
 F13a1
coagulation factor XIII, A1 subunit
chr8_-_110168204 3.998 ENSMUST00000003754.6
 Calb2
calbindin 2
chrY_+_90755657 2.962 ENSMUST00000167967.2
 Gm21857
predicted gene, 21857
chr12_+_58211772 2.867 ENSMUST00000110671.2
ENSMUST00000044299.2
 Sstr1

somatostatin receptor 1

chr19_+_12460749 2.737 ENSMUST00000081035.7
 Mpeg1
macrophage expressed gene 1
chr12_-_4592927 2.638 ENSMUST00000170816.1
 Gm3625
predicted gene 3625
chr1_+_104768510 2.468 ENSMUST00000062528.8
 Cdh20
cadherin 20
chr18_-_80986578 2.402 ENSMUST00000057950.7
 Sall3
sal-like 3 (Drosophila)
chr5_+_104435112 2.301 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
 Spp1





secreted phosphoprotein 1





chr3_+_68869563 2.294 ENSMUST00000054551.2
 1110032F04Rik
RIKEN cDNA 1110032F04 gene
chr15_+_57694651 2.213 ENSMUST00000096430.4
 Zhx2
zinc fingers and homeoboxes 2
chr1_+_178798438 2.120 ENSMUST00000160789.1
 Kif26b
kinesin family member 26B
chr4_+_128058962 2.085 ENSMUST00000184063.1
 Csmd2
CUB and Sushi multiple domains 2
chr14_+_51091077 2.053 ENSMUST00000022428.5
ENSMUST00000171688.1
 Rnase4
Ang
ribonuclease, RNase A family 4
angiogenin, ribonuclease, RNase A family, 5
chr17_+_22689771 2.045 ENSMUST00000055305.8
 Gm9805
predicted gene 9805
chr1_+_167598450 1.993 ENSMUST00000111386.1
ENSMUST00000111384.1
 Rxrg

retinoid X receptor gamma

chr5_+_112255813 1.974 ENSMUST00000031286.6
ENSMUST00000131673.1
ENSMUST00000112375.1
 Crybb1


crystallin, beta B1


chr4_-_40722307 1.910 ENSMUST00000181475.1
 Gm6297
predicted gene 6297

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 185 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 10.9 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.2 4.1 GO:0018149 peptide cross-linking(GO:0018149)
0.2 3.3 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.2 3.2 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.7 2.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 2.4 GO:0007601 visual perception(GO:0007601)
0.2 2.3 GO:0033280 response to vitamin D(GO:0033280)
0.1 2.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.0 2.2 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.7 2.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.7 2.1 GO:0019043 establishment of viral latency(GO:0019043)
0.7 2.1 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.2 2.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 2.1 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 1.9 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.4 1.8 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 1.8 GO:0048240 sperm capacitation(GO:0048240)
0.0 1.8 GO:0051480 regulation of cytosolic calcium ion concentration(GO:0051480)
0.2 1.7 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 1.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 19.1 GO:0005615 extracellular space(GO:0005615)
0.1 4.6 GO:0072562 blood microparticle(GO:0072562)
0.2 4.3 GO:0005921 gap junction(GO:0005921)
0.0 2.3 GO:0005802 trans-Golgi network(GO:0005802)
0.7 2.1 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.3 1.9 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.0 1.9 GO:0005871 kinesin complex(GO:0005871)
0.1 1.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.5 1.5 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.1 1.5 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 1.5 GO:0032587 ruffle membrane(GO:0032587)
0.3 1.4 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 1.4 GO:0002102 podosome(GO:0002102)
0.0 1.4 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.3 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.2 GO:0031985 Golgi cisterna(GO:0031985)
0.0 1.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.1 GO:0031209 SCAR complex(GO:0031209)
0.0 1.1 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.1 1.0 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 125 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 10.9 GO:0038191 neuropilin binding(GO:0038191)
1.0 4.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
1.0 2.9 GO:0004994 somatostatin receptor activity(GO:0004994)
0.4 2.9 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.3 2.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 2.3 GO:0005178 integrin binding(GO:0005178)
0.1 2.2 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 2.1 GO:0005507 copper ion binding(GO:0005507)
0.2 2.0 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 2.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 1.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 1.9 GO:0005003 ephrin receptor activity(GO:0005003)
0.3 1.8 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.8 GO:0005109 frizzled binding(GO:0005109)
0.0 1.8 GO:0008201 heparin binding(GO:0008201)
0.1 1.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.7 GO:0019955 cytokine binding(GO:0019955)
0.1 1.6 GO:0015026 coreceptor activity(GO:0015026)
0.1 1.6 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)