Motif ID: Hsf4

Z-value: 1.180


Transcription factors associated with Hsf4:

Gene SymbolEntrez IDGene Name
Hsf4 ENSMUSG00000033249.4 Hsf4



Activity profile for motif Hsf4.

activity profile for motif Hsf4


Sorted Z-values histogram for motif Hsf4

Sorted Z-values for motif Hsf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_109013389 2.572 ENSMUST00000033597.8
 Hmgn5
high-mobility group nucleosome binding domain 5
chr17_+_17316078 2.257 ENSMUST00000105311.3
 Gm6712
predicted gene 6712
chr17_+_17831004 2.176 ENSMUST00000172097.2
 4930546H06Rik
RIKEN cDNA 4930546H06 gene
chr13_-_62607499 1.765 ENSMUST00000091563.4
 6720489N17Rik
RIKEN cDNA 6720489N17 gene
chr12_+_75308308 1.667 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
 Rhoj


ras homolog gene family, member J


chr17_+_21707682 1.500 ENSMUST00000073312.6
 Zfp760
zinc finger protein 760
chr1_+_195017399 1.456 ENSMUST00000181273.1
 A330023F24Rik
RIKEN cDNA A330023F24 gene
chr2_+_150323702 1.435 ENSMUST00000133235.2
 Gm10130
predicted gene 10130
chr1_+_194938821 1.429 ENSMUST00000016638.2
ENSMUST00000110815.2
 Cd34

CD34 antigen

chr9_+_71215779 1.362 ENSMUST00000034723.5
 Aldh1a2
aldehyde dehydrogenase family 1, subfamily A2
chr14_-_65833963 1.288 ENSMUST00000022613.9
 Esco2
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr14_-_79390666 1.259 ENSMUST00000022597.7
 Naa16
N(alpha)-acetyltransferase 16, NatA auxiliary subunit
chrX_+_42149288 1.208 ENSMUST00000115073.2
ENSMUST00000115072.1
 Stag2

stromal antigen 2

chr9_+_13827708 1.190 ENSMUST00000059579.5
 Fam76b
family with sequence similarity 76, member B
chr1_-_189688074 1.185 ENSMUST00000171929.1
ENSMUST00000165962.1
 Cenpf

centromere protein F

chr18_-_70472429 1.166 ENSMUST00000067556.3
 4930503L19Rik
RIKEN cDNA 4930503L19 gene
chr10_+_86302854 1.165 ENSMUST00000132307.1
 Timp3
tissue inhibitor of metalloproteinase 3
chrX_+_73214333 1.153 ENSMUST00000156188.1
ENSMUST00000069077.3
ENSMUST00000069103.4
ENSMUST00000114506.1
ENSMUST00000081827.3
 Xlr4b




X-linked lymphocyte-regulated 4B




chr10_+_100488289 1.119 ENSMUST00000164751.1
 Cep290
centrosomal protein 290
chr13_+_81657732 1.093 ENSMUST00000049055.6
 Lysmd3
LysM, putative peptidoglycan-binding, domain containing 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 118 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 3.3 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 3.0 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 2.4 GO:0006749 glutathione metabolic process(GO:0006749)
0.5 1.9 GO:0042938 dipeptide transport(GO:0042938)
0.0 1.8 GO:0000060 protein import into nucleus, translocation(GO:0000060)
0.1 1.7 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 1.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.3 1.5 GO:1905049 negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049)
0.5 1.4 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.5 1.4 GO:0035799 ureter maturation(GO:0035799)
0.4 1.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.3 1.3 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 1.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 1.2 GO:0051310 ventricular system development(GO:0021591) metaphase plate congression(GO:0051310)
0.0 1.2 GO:0061003 positive regulation of dendritic spine morphogenesis(GO:0061003)
0.1 1.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 1.1 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.3 1.0 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.3 1.0 GO:0035701 hematopoietic stem cell migration(GO:0035701)
0.2 1.0 GO:0002457 T cell antigen processing and presentation(GO:0002457)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 50 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.7 3.3 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.2 3.0 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 2.5 GO:0045111 intermediate filament cytoskeleton(GO:0045111)
0.0 1.6 GO:0005604 basement membrane(GO:0005604)
0.1 1.4 GO:0046930 pore complex(GO:0046930)
0.2 1.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.2 1.3 GO:0031415 NatA complex(GO:0031415)
0.1 1.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 1.1 GO:0036038 MKS complex(GO:0036038)
0.1 1.0 GO:0042629 mast cell granule(GO:0042629)
0.3 0.9 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 0.8 GO:0033503 HULC complex(GO:0033503)
0.0 0.8 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.2 0.6 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.6 GO:0000938 GARP complex(GO:0000938)
0.1 0.6 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.6 GO:0097433 dense body(GO:0097433) HFE-transferrin receptor complex(GO:1990712)
0.1 0.6 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.3 GO:0030911 TPR domain binding(GO:0030911)
0.2 3.0 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 2.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.4 1.9 GO:0042895 antibiotic transporter activity(GO:0042895)
0.1 1.7 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 1.6 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 1.4 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.3 1.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 1.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.2 GO:0045502 dynein binding(GO:0045502)
0.3 1.0 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.3 0.9 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.9 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.8 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.8 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 0.7 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.7 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.7 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.2 0.6 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)