Motif ID: Id4

Z-value: 1.253


Transcription factors associated with Id4:

Gene SymbolEntrez IDGene Name
Id4 ENSMUSG00000021379.1 Id4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Id4mm10_v2_chr13_+_48261427_48261427-0.411.5e-01Click!


Activity profile for motif Id4.

activity profile for motif Id4


Sorted Z-values histogram for motif Id4

Sorted Z-values for motif Id4



Network of associatons between targets according to the STRING database.



First level regulatory network of Id4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_98854434 3.024 ENSMUST00000031278.4
 Bmp3
bone morphogenetic protein 3
chr11_-_95587691 2.328 ENSMUST00000000122.6
 Ngfr
nerve growth factor receptor (TNFR superfamily, member 16)
chr4_+_125490688 2.172 ENSMUST00000030676.7
 Grik3
glutamate receptor, ionotropic, kainate 3
chr7_+_123982799 2.141 ENSMUST00000106437.1
 Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr13_-_57907587 1.978 ENSMUST00000172326.1
 Spock1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 1
chr11_+_42419729 1.945 ENSMUST00000007797.4
 Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr11_-_7213897 1.785 ENSMUST00000020702.4
ENSMUST00000135887.2
 Igfbp3

insulin-like growth factor binding protein 3

chr2_+_49619277 1.735 ENSMUST00000028102.7
 Kif5c
kinesin family member 5C
chr15_-_64922290 1.719 ENSMUST00000023007.5
 Adcy8
adenylate cyclase 8
chr7_+_121707189 1.713 ENSMUST00000065310.2
 1700069B07Rik
RIKEN cDNA 1700069B07 gene
chr3_+_75557530 1.661 ENSMUST00000161776.1
ENSMUST00000029423.8
 Serpini1

serine (or cysteine) peptidase inhibitor, clade I, member 1

chr2_-_57114970 1.643 ENSMUST00000028166.2
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr18_-_42899470 1.607 ENSMUST00000120632.1
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr15_-_60824942 1.599 ENSMUST00000100635.3
 Fam84b
family with sequence similarity 84, member B
chr12_+_82616885 1.592 ENSMUST00000161801.1
 Rgs6
regulator of G-protein signaling 6
chr1_+_153740344 1.560 ENSMUST00000027748.7
 Rgs16
regulator of G-protein signaling 16
chr11_-_51756378 1.546 ENSMUST00000109092.1
ENSMUST00000064297.4
ENSMUST00000109097.2
 Sec24a


Sec24 related gene family, member A (S. cerevisiae)


chr8_+_83389846 1.524 ENSMUST00000002259.6
 Clgn
calmegin
chr14_-_102982630 1.496 ENSMUST00000184744.1
 KCTD12
mmu-mir-5130
chr8_-_40634750 1.450 ENSMUST00000173957.1
 Mtmr7
myotubularin related protein 7

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 282 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 3.3 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.1 3.0 GO:0035036 binding of sperm to zona pellucida(GO:0007339) sperm-egg recognition(GO:0035036)
0.4 2.7 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
0.1 2.5 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 2.5 GO:0043547 positive regulation of GTPase activity(GO:0043547)
0.8 2.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.1 2.3 GO:0008045 motor neuron axon guidance(GO:0008045)
0.7 2.2 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.2 2.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.2 2.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 2.2 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.3 2.1 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 2.1 GO:0010812 negative regulation of cell-substrate adhesion(GO:0010812)
0.0 2.1 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 1.9 GO:0071420 cellular response to histamine(GO:0071420)
0.4 1.8 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512) positive regulation of DNA catabolic process(GO:1903626)
0.4 1.8 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 1.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 1.7 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.1 1.7 GO:0006471 protein ADP-ribosylation(GO:0006471)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 115 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.9 GO:0043195 terminal bouton(GO:0043195)
0.1 3.5 GO:0032590 dendrite membrane(GO:0032590)
0.1 3.3 GO:0090544 BAF-type complex(GO:0090544)
0.0 3.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.1 2.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.7 GO:0016605 PML body(GO:0016605)
0.5 2.3 GO:1990761 growth cone lamellipodium(GO:1990761)
0.1 2.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 2.3 GO:0030117 membrane coat(GO:0030117) coated membrane(GO:0048475)
0.1 1.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.4 1.8 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.0 1.7 GO:0005871 kinesin complex(GO:0005871)
0.3 1.6 GO:0045179 apical cortex(GO:0045179)
0.1 1.6 GO:0035253 ciliary rootlet(GO:0035253)
0.3 1.5 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 1.5 GO:0033268 node of Ranvier(GO:0033268)
0.5 1.4 GO:0048179 activin receptor complex(GO:0048179)
0.2 1.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 1.4 GO:0000780 condensed nuclear chromosome, centromeric region(GO:0000780)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 183 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.2 3.0 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 2.9 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.0 2.9 GO:0017124 SH3 domain binding(GO:0017124)
0.4 2.7 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.2 2.7 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.0 2.7 GO:0005096 GTPase activator activity(GO:0005096)
0.1 2.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 2.3 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.2 2.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 2.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.2 GO:0030552 cAMP binding(GO:0030552)
0.7 2.1 GO:0001565 phorbol ester receptor activity(GO:0001565) non-kinase phorbol ester receptor activity(GO:0001566)
0.1 2.1 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.0 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.5 1.9 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.4 1.8 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 1.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.6 1.7 GO:0034190 apolipoprotein receptor binding(GO:0034190)