Motif ID: Ikzf2

Z-value: 1.136


Transcription factors associated with Ikzf2:

Gene SymbolEntrez IDGene Name
Ikzf2 ENSMUSG00000025997.7 Ikzf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ikzf2mm10_v2_chr1_-_69685937_696859660.214.8e-01Click!


Activity profile for motif Ikzf2.

activity profile for motif Ikzf2


Sorted Z-values histogram for motif Ikzf2

Sorted Z-values for motif Ikzf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ikzf2

PNG image of the network

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Top targets:


Showing 1 to 20 of 97 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_103422010 8.762 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr15_+_3270767 7.378 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr5_-_123141067 5.752 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
 AI480526


expressed sequence AI480526


chr1_+_45311538 2.853 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr9_-_42944479 2.021 ENSMUST00000114865.1
 Grik4
glutamate receptor, ionotropic, kainate 4
chr6_+_4003926 1.993 ENSMUST00000031670.8
 Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr5_-_123140135 1.860 ENSMUST00000160099.1
 AI480526
expressed sequence AI480526
chr6_+_15185203 1.852 ENSMUST00000154448.1
 Foxp2
forkhead box P2
chr2_-_71546745 1.701 ENSMUST00000024159.6
 Dlx2
distal-less homeobox 2
chr3_+_88214474 1.622 ENSMUST00000181356.1
ENSMUST00000181396.1
 Gm3764

predicted gene 3764

chr11_-_55419898 1.439 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr12_+_75308308 1.336 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
 Rhoj


ras homolog gene family, member J


chr5_-_134747241 1.249 ENSMUST00000015138.9
 Eln
elastin
chr1_-_45503282 1.187 ENSMUST00000086430.4
 Col5a2
collagen, type V, alpha 2
chr1_-_162866502 1.169 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr2_-_77170592 1.163 ENSMUST00000164114.2
ENSMUST00000049544.7
 Ccdc141

coiled-coil domain containing 141

chr13_-_103764502 1.126 ENSMUST00000074616.5
 Srek1
splicing regulatory glutamine/lysine-rich protein 1
chr3_-_116129615 1.075 ENSMUST00000029574.8
 Vcam1
vascular cell adhesion molecule 1
chr14_+_54936456 1.045 ENSMUST00000037814.6
 Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr4_+_105157339 1.012 ENSMUST00000064139.7
 Ppap2b
phosphatidic acid phosphatase type 2B

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 7.4 GO:0001887 selenium compound metabolic process(GO:0001887)
0.6 2.9 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 2.1 GO:0043062 extracellular matrix organization(GO:0030198) extracellular structure organization(GO:0043062)
0.2 1.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.6 1.7 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.0 1.4 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.1 1.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.4 1.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 1.2 GO:0009404 toxin metabolic process(GO:0009404)
0.0 1.2 GO:0051642 centrosome localization(GO:0051642)
0.1 1.1 GO:0061032 visceral serous pericardium development(GO:0061032)
0.2 1.0 GO:1903026 negative regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903026)
0.0 1.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.3 0.9 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.2 0.9 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199) positive regulation of blood vessel remodeling(GO:2000504)
0.2 0.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.8 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.6 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441)
0.0 0.6 GO:0010107 potassium ion import(GO:0010107)
0.3 0.5 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 2.9 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 2.3 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.3 2.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.4 1.4 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.4 1.2 GO:0071953 elastic fiber(GO:0071953)
0.4 1.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 1.0 GO:0005719 nuclear euchromatin(GO:0005719)
0.0 0.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.7 GO:0002102 podosome(GO:0002102)
0.1 0.4 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.2 GO:0034679 integrin alpha2-beta1 complex(GO:0034666) integrin alpha3-beta1 complex(GO:0034667) integrin alpha9-beta1 complex(GO:0034679)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 7.4 GO:0008430 selenium binding(GO:0008430)
0.1 3.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 2.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 2.1 GO:0003727 single-stranded RNA binding(GO:0003727)
0.1 2.0 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 1.4 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 1.3 GO:0070888 E-box binding(GO:0070888)
0.2 1.2 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.3 1.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 0.9 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.9 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 0.7 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.6 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 0.5 GO:0016936 galactoside binding(GO:0016936)
0.1 0.5 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.4 GO:0050816 phosphothreonine binding(GO:0050816)
0.1 0.3 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.3 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)