Motif ID: Insm1

Z-value: 0.560


Transcription factors associated with Insm1:

Gene SymbolEntrez IDGene Name
Insm1 ENSMUSG00000068154.4 Insm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Insm1mm10_v2_chr2_+_146221921_1462219210.362.1e-01Click!


Activity profile for motif Insm1.

activity profile for motif Insm1


Sorted Z-values histogram for motif Insm1

Sorted Z-values for motif Insm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Insm1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr19_+_4154606 0.748 ENSMUST00000061086.8
Ptprcap
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr3_+_156562141 0.666 ENSMUST00000175773.1
Negr1
neuronal growth regulator 1
chr4_-_108383349 0.628 ENSMUST00000053157.6
Fam159a
family with sequence similarity 159, member A
chr3_+_156561950 0.619 ENSMUST00000041425.5
ENSMUST00000106065.1
Negr1

neuronal growth regulator 1

chr3_+_156561792 0.516 ENSMUST00000074015.4
Negr1
neuronal growth regulator 1
chr2_+_26583858 0.468 ENSMUST00000100290.5
ENSMUST00000102907.5
Egfl7

EGF-like domain 7

chr2_+_109280738 0.440 ENSMUST00000028527.7
Kif18a
kinesin family member 18A
chr7_+_51878967 0.428 ENSMUST00000051912.6
Gas2
growth arrest specific 2
chr13_-_21780616 0.419 ENSMUST00000080511.2
Hist1h1b
histone cluster 1, H1b
chr7_+_51879041 0.413 ENSMUST00000107591.2
Gas2
growth arrest specific 2
chr4_-_153482768 0.402 ENSMUST00000105646.2
Ajap1
adherens junction associated protein 1
chr18_+_64340225 0.346 ENSMUST00000175965.2
ENSMUST00000115145.3
Onecut2

one cut domain, family member 2

chr17_+_47688992 0.334 ENSMUST00000156118.1
Frs3
fibroblast growth factor receptor substrate 3
chr3_-_101604580 0.315 ENSMUST00000036493.6
Atp1a1
ATPase, Na+/K+ transporting, alpha 1 polypeptide
chr11_-_115813621 0.310 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr12_+_119945957 0.302 ENSMUST00000058644.8
Tmem196
transmembrane protein 196
chr15_-_99370427 0.302 ENSMUST00000081224.7
ENSMUST00000120633.1
ENSMUST00000088233.6
Fmnl3


formin-like 3


chr5_-_115436508 0.302 ENSMUST00000078701.3
4930430O22Rik
RIKEN cDNA 4930430O22 gene
chr10_+_80805233 0.276 ENSMUST00000036016.4
Amh
anti-Mullerian hormone
chr2_+_52072823 0.272 ENSMUST00000112693.2
ENSMUST00000069794.5
Rif1

Rap1 interacting factor 1 homolog (yeast)

chr3_-_104818539 0.253 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Mov10



Moloney leukemia virus 10



chr17_-_35516780 0.248 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
Tcf19


transcription factor 19


chr12_+_77239036 0.245 ENSMUST00000062804.7
Fut8
fucosyltransferase 8
chr11_-_77894096 0.244 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr7_-_31055594 0.225 ENSMUST00000039909.6
Fxyd1
FXYD domain-containing ion transport regulator 1
chrX_+_68678541 0.218 ENSMUST00000088546.5
Fmr1
fragile X mental retardation syndrome 1
chr11_-_69880971 0.204 ENSMUST00000050555.3
Kctd11
potassium channel tetramerisation domain containing 11
chr7_+_16842896 0.203 ENSMUST00000168093.2
Prkd2
protein kinase D2
chr15_-_54919961 0.202 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
Enpp2


ectonucleotide pyrophosphatase/phosphodiesterase 2


chr7_+_144838590 0.200 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr16_-_67620880 0.197 ENSMUST00000114292.1
ENSMUST00000120898.1
Cadm2

cell adhesion molecule 2

chr7_+_141461075 0.189 ENSMUST00000053670.5
Efcab4a
EF-hand calcium binding domain 4A
chrX_-_53670397 0.189 ENSMUST00000088778.3
Cxx1b
CAAX box 1B
chr14_+_63606491 0.183 ENSMUST00000119973.2
Xkr6
X Kell blood group precursor related family member 6 homolog
chrX_+_68678712 0.179 ENSMUST00000114654.1
ENSMUST00000114655.1
ENSMUST00000114657.2
ENSMUST00000114653.1
Fmr1



fragile X mental retardation syndrome 1



chr15_-_54920115 0.175 ENSMUST00000171545.1
Enpp2
ectonucleotide pyrophosphatase/phosphodiesterase 2
chrX_+_68678624 0.167 ENSMUST00000114656.1
Fmr1
fragile X mental retardation syndrome 1
chr7_-_101933815 0.165 ENSMUST00000106963.1
ENSMUST00000106966.1
Lrrc51

leucine rich repeat containing 51

chr7_+_6286589 0.161 ENSMUST00000170776.1
Zfp667
zinc finger protein 667
chr7_+_6286573 0.158 ENSMUST00000086327.5
Zfp667
zinc finger protein 667
chr4_-_88033328 0.157 ENSMUST00000078090.5
Mllt3
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr19_+_56874249 0.150 ENSMUST00000026068.7
Vwa2
von Willebrand factor A domain containing 2
chr7_-_118995211 0.140 ENSMUST00000008878.8
Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr2_+_28205648 0.138 ENSMUST00000102879.3
ENSMUST00000028177.4
Olfm1

olfactomedin 1

chr5_-_31202215 0.137 ENSMUST00000176245.1
ENSMUST00000177310.1
ENSMUST00000114590.1
Zfp513


zinc finger protein 513


chr9_+_108808356 0.135 ENSMUST00000035218.7
Nckipsd
NCK interacting protein with SH3 domain
chr6_+_6863269 0.134 ENSMUST00000160937.2
ENSMUST00000171311.1
Dlx6

distal-less homeobox 6

chr11_+_60105079 0.131 ENSMUST00000132012.1
Rai1
retinoic acid induced 1
chr11_+_58104229 0.120 ENSMUST00000108843.1
ENSMUST00000134896.1
Cnot8

CCR4-NOT transcription complex, subunit 8

chr12_+_51593315 0.118 ENSMUST00000164782.2
ENSMUST00000085412.5
Coch

coagulation factor C homolog (Limulus polyphemus)

chr2_-_127521358 0.118 ENSMUST00000028850.8
ENSMUST00000103215.4
Kcnip3

Kv channel interacting protein 3, calsenilin

chr8_-_69902712 0.115 ENSMUST00000180068.1
Yjefn3
YjeF N-terminal domain containing 3
chr19_+_4003334 0.110 ENSMUST00000025806.3
Doc2g
double C2, gamma
chr15_+_78428564 0.110 ENSMUST00000166142.2
ENSMUST00000162517.1
ENSMUST00000089414.4
Kctd17


potassium channel tetramerisation domain containing 17


chr6_+_42286676 0.106 ENSMUST00000031894.6
Clcn1
chloride channel 1
chr2_+_25242929 0.101 ENSMUST00000114355.1
ENSMUST00000060818.1
Rnf208

ring finger protein 208

chr16_-_67620805 0.101 ENSMUST00000120594.1
Cadm2
cell adhesion molecule 2
chr2_-_72980402 0.100 ENSMUST00000066003.6
ENSMUST00000102689.3
Sp3

trans-acting transcription factor 3

chr1_+_192190771 0.100 ENSMUST00000078470.5
ENSMUST00000110844.1
Kcnh1

potassium voltage-gated channel, subfamily H (eag-related), member 1

chr10_-_42276688 0.094 ENSMUST00000175881.1
ENSMUST00000056974.3
Foxo3

forkhead box O3

chr7_-_122067263 0.092 ENSMUST00000033159.3
Ears2
glutamyl-tRNA synthetase 2 (mitochondrial)(putative)
chr7_-_45016224 0.089 ENSMUST00000085383.2
Scaf1
SR-related CTD-associated factor 1
chr13_+_12565868 0.089 ENSMUST00000071973.6
Ero1lb
ERO1-like beta (S. cerevisiae)
chr7_+_4690760 0.088 ENSMUST00000048248.7
Brsk1
BR serine/threonine kinase 1
chr7_+_127746775 0.088 ENSMUST00000033081.7
Fbxl19
F-box and leucine-rich repeat protein 19
chr15_+_78428650 0.088 ENSMUST00000159771.1
Kctd17
potassium channel tetramerisation domain containing 17
chr11_-_70687917 0.087 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
Camta2




calmodulin binding transcription activator 2




chr4_-_130174691 0.087 ENSMUST00000132545.2
ENSMUST00000175992.1
ENSMUST00000105999.2
Tinagl1


tubulointerstitial nephritis antigen-like 1


chr7_-_45814302 0.087 ENSMUST00000107729.1
ENSMUST00000056820.6
Cyth2

cytohesin 2

chr7_+_4690604 0.086 ENSMUST00000120836.1
Brsk1
BR serine/threonine kinase 1
chr2_-_122369130 0.079 ENSMUST00000151130.1
ENSMUST00000125826.1
Shf

Src homology 2 domain containing F

chr9_+_107569112 0.078 ENSMUST00000010191.7
Hyal2
hyaluronoglucosaminidase 2
chr19_+_44992127 0.078 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr7_-_45814277 0.077 ENSMUST00000107728.1
Cyth2
cytohesin 2
chr16_+_18248866 0.077 ENSMUST00000115640.1
ENSMUST00000140206.1
Trmt2a

TRM2 tRNA methyltransferase 2A

chrX_+_9199865 0.075 ENSMUST00000069763.2
Lancl3
LanC lantibiotic synthetase component C-like 3 (bacterial)
chr10_+_96616998 0.072 ENSMUST00000038377.7
Btg1
B cell translocation gene 1, anti-proliferative
chr14_+_21499770 0.072 ENSMUST00000182855.1
ENSMUST00000069648.7
ENSMUST00000182405.1
Kat6b


K(lysine) acetyltransferase 6B


chr7_-_19715395 0.070 ENSMUST00000032555.9
ENSMUST00000093552.5
Tomm40

translocase of outer mitochondrial membrane 40 homolog (yeast)

chr7_+_5056706 0.067 ENSMUST00000144802.1
Ccdc106
coiled-coil domain containing 106
chr5_-_125434048 0.067 ENSMUST00000169485.1
Dhx37
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr7_+_4740178 0.067 ENSMUST00000108583.2
Suv420h2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr7_+_4740111 0.065 ENSMUST00000098853.2
Suv420h2
suppressor of variegation 4-20 homolog 2 (Drosophila)
chr11_+_58104138 0.063 ENSMUST00000020822.5
Cnot8
CCR4-NOT transcription complex, subunit 8
chr10_+_121365078 0.063 ENSMUST00000040344.6
Gns
glucosamine (N-acetyl)-6-sulfatase
chr14_-_31830402 0.061 ENSMUST00000014640.7
Ankrd28
ankyrin repeat domain 28
chr7_+_27473761 0.061 ENSMUST00000068641.6
Sertad3
SERTA domain containing 3
chr11_+_106084577 0.058 ENSMUST00000002044.9
Map3k3
mitogen-activated protein kinase kinase kinase 3
chr7_-_29156160 0.056 ENSMUST00000144795.1
ENSMUST00000134176.1
ENSMUST00000164589.1
ENSMUST00000136256.1
Fam98c



family with sequence similarity 98, member C



chr15_-_50890396 0.056 ENSMUST00000185183.1
Trps1
trichorhinophalangeal syndrome I (human)
chr14_-_20794009 0.055 ENSMUST00000100837.3
ENSMUST00000080440.6
ENSMUST00000071816.6
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr2_-_152831112 0.052 ENSMUST00000128172.1
Bcl2l1
BCL2-like 1
chr3_+_145938004 0.049 ENSMUST00000039571.7
2410004B18Rik
RIKEN cDNA 2410004B18 gene
chr6_-_72362382 0.048 ENSMUST00000114095.1
ENSMUST00000069595.6
ENSMUST00000069580.5
Rnf181


ring finger protein 181


chr3_-_41082992 0.046 ENSMUST00000058578.7
Pgrmc2
progesterone receptor membrane component 2
chr7_+_79660196 0.046 ENSMUST00000035977.7
Ticrr
TOPBP1-interacting checkpoint and replication regulator
chr19_+_5637475 0.045 ENSMUST00000025867.5
Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr8_+_71469186 0.045 ENSMUST00000124745.1
ENSMUST00000138892.1
ENSMUST00000147642.1
Dda1


DET1 and DDB1 associated 1


chr10_-_116473418 0.044 ENSMUST00000087965.4
ENSMUST00000164271.1
Kcnmb4

potassium large conductance calcium-activated channel, subfamily M, beta member 4

chr6_+_42286709 0.042 ENSMUST00000163936.1
Clcn1
chloride channel 1
chr13_+_63815240 0.041 ENSMUST00000021926.5
ENSMUST00000095724.3
ENSMUST00000143449.1
ENSMUST00000067821.5
Ercc6l2



excision repair cross-complementing rodent repair deficiency, complementation group 6 like 2



chr19_-_7206234 0.039 ENSMUST00000123594.1
ENSMUST00000025679.4
Otub1

OTU domain, ubiquitin aldehyde binding 1

chrX_-_103981242 0.039 ENSMUST00000121153.1
ENSMUST00000070705.4
Rlim

ring finger protein, LIM domain interacting

chr16_+_18248961 0.039 ENSMUST00000100099.3
Trmt2a
TRM2 tRNA methyltransferase 2A
chr4_-_44710408 0.039 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
Pax5









paired box gene 5









chr17_-_46680870 0.038 ENSMUST00000165007.1
ENSMUST00000071841.5
Klhdc3

kelch domain containing 3

chr7_+_30553263 0.038 ENSMUST00000044048.7
Hspb6
heat shock protein, alpha-crystallin-related, B6
chr2_+_154436437 0.038 ENSMUST00000109725.1
ENSMUST00000099178.3
ENSMUST00000045270.8
ENSMUST00000109724.1
Cbfa2t2



core-binding factor, runt domain, alpha subunit 2, translocated to, 2 (human)



chr7_+_4740137 0.037 ENSMUST00000130215.1
ENSMUST00000108582.3
Suv420h2

suppressor of variegation 4-20 homolog 2 (Drosophila)

chr5_-_122264378 0.033 ENSMUST00000111738.3
Tctn1
tectonic family member 1
chr19_+_4756557 0.033 ENSMUST00000036744.7
Rbm4b
RNA binding motif protein 4B
chr2_+_11172382 0.030 ENSMUST00000028118.3
Prkcq
protein kinase C, theta
chr14_+_54625305 0.026 ENSMUST00000097177.4
Psmb11
proteasome (prosome, macropain) subunit, beta type, 11
chr1_+_87620334 0.021 ENSMUST00000042275.8
ENSMUST00000168783.1
Inpp5d

inositol polyphosphate-5-phosphatase D

chr10_-_82623190 0.016 ENSMUST00000183363.1
ENSMUST00000079648.5
ENSMUST00000185168.1
1190007I07Rik


RIKEN cDNA 1190007I07 gene


chr7_-_28766469 0.014 ENSMUST00000085851.5
ENSMUST00000032815.4
Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr2_+_174330006 0.010 ENSMUST00000109085.1
ENSMUST00000109087.1
ENSMUST00000109084.1
Gnas


GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus


chr17_-_32166879 0.010 ENSMUST00000087723.3
Notch3
notch 3
chr7_-_126369543 0.008 ENSMUST00000032997.6
Lat
linker for activation of T cells
chr5_+_111417263 0.007 ENSMUST00000094463.4
Mn1
meningioma 1
chr10_-_116950366 0.004 ENSMUST00000020375.6
Rab3ip
RAB3A interacting protein
chrX_+_99975570 0.004 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
Eda








ectodysplasin-A








chr7_+_5057161 0.003 ENSMUST00000045543.5
Ccdc106
coiled-coil domain containing 106
chrX_+_153006461 0.000 ENSMUST00000095755.3
Usp51
ubiquitin specific protease 51

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1901254 positive regulation of intracellular transport of viral material(GO:1901254)
0.1 0.3 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.1 0.2 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 0.2 GO:0006553 lysine metabolic process(GO:0006553)
0.1 0.3 GO:1903416 response to glycoside(GO:1903416)
0.1 0.2 GO:1903795 regulation of inorganic anion transmembrane transport(GO:1903795)
0.1 0.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.1 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.1 0.4 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.0 0.2 GO:0089700 positive regulation of T cell receptor signaling pathway(GO:0050862) protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0030070 insulin processing(GO:0030070)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.4 GO:0072520 seminiferous tubule development(GO:0072520)
0.0 0.2 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.0 0.1 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.1 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.0 0.1 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.2 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.1 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.0 1.7 GO:0007631 feeding behavior(GO:0007631)
0.0 0.2 GO:0007379 segment specification(GO:0007379)
0.0 0.1 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0001542 ovulation from ovarian follicle(GO:0001542) positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0 0.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.0 0.1 GO:2001223 neuronal signal transduction(GO:0023041) negative regulation of neuron migration(GO:2001223)
0.0 0.1 GO:0043353 enucleate erythrocyte differentiation(GO:0043353)
0.0 0.0 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.3 GO:0006379 mRNA cleavage(GO:0006379)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0042025 viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.1 0.4 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 1.9 GO:0031225 anchored component of membrane(GO:0031225)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.4 GO:0004528 phosphodiesterase I activity(GO:0004528)
0.1 0.2 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.0 0.3 GO:0103116 alpha-D-galactofuranose transporter activity(GO:0103116) steroid hormone binding(GO:1990239)
0.0 0.4 GO:0051010 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0042799 histone methyltransferase activity (H4-K20 specific)(GO:0042799)
0.0 0.1 GO:0030292 hyalurononglucosaminidase activity(GO:0004415) protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.1 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.0 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.2 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)