Motif ID: Irf3
Z-value: 1.156
Transcription factors associated with Irf3:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Irf3 | ENSMUSG00000003184.8 | Irf3 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Irf3 | mm10_v2_chr7_+_44997648_44997700 | 0.28 | 3.3e-01 | Click! |
Top targets:
Showing 1 to 20 of 84 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 29 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 3.9 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
| 0.5 | 2.7 | GO:1900122 | positive regulation of receptor binding(GO:1900122) |
| 0.2 | 2.5 | GO:0044406 | adhesion of symbiont to host(GO:0044406) |
| 0.3 | 2.4 | GO:0060330 | regulation of response to interferon-gamma(GO:0060330) |
| 0.0 | 1.1 | GO:0035456 | response to interferon-beta(GO:0035456) |
| 0.1 | 1.0 | GO:0032020 | ISG15-protein conjugation(GO:0032020) |
| 0.0 | 0.9 | GO:0016082 | synaptic vesicle priming(GO:0016082) |
| 0.2 | 0.8 | GO:0009597 | detection of virus(GO:0009597) |
| 0.2 | 0.8 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.1 | 0.8 | GO:0042590 | antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590) |
| 0.1 | 0.7 | GO:0010991 | negative regulation of SMAD protein complex assembly(GO:0010991) |
| 0.0 | 0.7 | GO:0055070 | copper ion homeostasis(GO:0055070) |
| 0.0 | 0.7 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.0 | 0.7 | GO:0045071 | negative regulation of viral genome replication(GO:0045071) |
| 0.1 | 0.6 | GO:0060340 | positive regulation of type I interferon-mediated signaling pathway(GO:0060340) |
| 0.1 | 0.5 | GO:0036438 | maintenance of lens transparency(GO:0036438) |
| 0.2 | 0.4 | GO:0002578 | negative regulation of antigen processing and presentation(GO:0002578) |
| 0.1 | 0.4 | GO:0034124 | regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) |
| 0.1 | 0.4 | GO:0006059 | hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401) |
| 0.1 | 0.4 | GO:0010528 | regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529) |
Gene overrepresentation in cellular_component category:
Showing 1 to 16 of 16 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 2.8 | GO:0020003 | symbiont-containing vacuole(GO:0020003) |
| 0.3 | 2.7 | GO:1990712 | HFE-transferrin receptor complex(GO:1990712) |
| 0.0 | 2.7 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.7 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.4 | 1.2 | GO:0042025 | viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 0.0 | 1.1 | GO:0036126 | sperm flagellum(GO:0036126) |
| 0.0 | 0.9 | GO:0042734 | presynaptic membrane(GO:0042734) |
| 0.1 | 0.8 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.2 | 0.7 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
| 0.0 | 0.7 | GO:0031901 | early endosome membrane(GO:0031901) |
| 0.1 | 0.5 | GO:0008537 | proteasome activator complex(GO:0008537) |
| 0.1 | 0.4 | GO:0097454 | Schwann cell microvillus(GO:0097454) |
| 0.0 | 0.3 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.0 | 0.3 | GO:0030914 | STAGA complex(GO:0030914) |
| 0.0 | 0.1 | GO:0097233 | lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233) |
| 0.0 | 0.1 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 25 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 4.0 | GO:0003950 | NAD+ ADP-ribosyltransferase activity(GO:0003950) |
| 0.2 | 2.7 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.0 | 2.2 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.1 | 1.9 | GO:0070566 | adenylyltransferase activity(GO:0070566) |
| 0.1 | 1.6 | GO:0070006 | metalloaminopeptidase activity(GO:0070006) |
| 0.0 | 1.6 | GO:0001948 | glycoprotein binding(GO:0001948) |
| 0.2 | 1.2 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.0 | 1.2 | GO:0051082 | unfolded protein binding(GO:0051082) |
| 0.1 | 1.0 | GO:0039706 | co-receptor binding(GO:0039706) |
| 0.1 | 1.0 | GO:0031386 | protein tag(GO:0031386) |
| 0.2 | 0.8 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.0 | 0.8 | GO:0015036 | disulfide oxidoreductase activity(GO:0015036) |
| 0.0 | 0.8 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
| 0.0 | 0.8 | GO:0004197 | cysteine-type endopeptidase activity(GO:0004197) |
| 0.2 | 0.7 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.0 | 0.7 | GO:0050699 | WW domain binding(GO:0050699) |
| 0.2 | 0.6 | GO:0003692 | left-handed Z-DNA binding(GO:0003692) |
| 0.1 | 0.6 | GO:0061133 | endopeptidase activator activity(GO:0061133) |
| 0.0 | 0.6 | GO:0005507 | copper ion binding(GO:0005507) |
| 0.2 | 0.5 | GO:0008109 | N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109) |
