Motif ID: Irx4

Z-value: 0.287


Transcription factors associated with Irx4:

Gene SymbolEntrez IDGene Name
Irx4 ENSMUSG00000021604.9 Irx4



Activity profile for motif Irx4.

activity profile for motif Irx4


Sorted Z-values histogram for motif Irx4

Sorted Z-values for motif Irx4



Network of associatons between targets according to the STRING database.


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_45311538 0.781 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr11_-_11970540 0.321 ENSMUST00000109653.1
 Grb10
growth factor receptor bound protein 10
chr2_-_79908428 0.221 ENSMUST00000102652.3
ENSMUST00000102651.3
 Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr15_-_35938009 0.196 ENSMUST00000156915.1
 Cox6c
cytochrome c oxidase subunit VIc
chr14_-_30353468 0.184 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr8_+_84872105 0.174 ENSMUST00000136026.1
ENSMUST00000170296.1
 Syce2

synaptonemal complex central element protein 2

chr2_-_79908389 0.163 ENSMUST00000090756.4
 Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr18_-_37178493 0.136 ENSMUST00000181887.1
ENSMUST00000180516.1
 Gm10544

predicted gene 10544

chr9_-_58202281 0.136 ENSMUST00000163897.1
 Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr6_-_3494587 0.118 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr15_-_35938186 0.114 ENSMUST00000014457.8
 Cox6c
cytochrome c oxidase subunit VIc
chr17_-_25785324 0.106 ENSMUST00000150324.1
 Haghl
hydroxyacylglutathione hydrolase-like
chr17_-_25785533 0.074 ENSMUST00000140738.1
ENSMUST00000145053.1
ENSMUST00000138759.1
ENSMUST00000133071.1
ENSMUST00000077938.3
 Haghl




hydroxyacylglutathione hydrolase-like




chr4_+_48663502 0.051 ENSMUST00000030033.4
 Murc
muscle-related coiled-coil protein
chr3_+_27317028 0.007 ENSMUST00000046383.5
ENSMUST00000174840.1
 Tnfsf10

tumor necrosis factor (ligand) superfamily, member 10


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.2 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.3 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.2 GO:0007130 synaptonemal complex assembly(GO:0007130)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.2 GO:0000801 central element(GO:0000801)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.8 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.2 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)