Motif ID: Jun

Z-value: 0.931


Transcription factors associated with Jun:

Gene SymbolEntrez IDGene Name
Jun ENSMUSG00000052684.3 Jun

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Junmm10_v2_chr4_-_95052170_950521810.732.9e-03Click!


Activity profile for motif Jun.

activity profile for motif Jun


Sorted Z-values histogram for motif Jun

Sorted Z-values for motif Jun



Network of associatons between targets according to the STRING database.



First level regulatory network of Jun

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_25395866 4.078 ENSMUST00000028328.2
 Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr3_+_109573907 3.808 ENSMUST00000106576.2
 Vav3
vav 3 oncogene
chr2_-_77703252 3.562 ENSMUST00000171063.1
 Zfp385b
zinc finger protein 385B
chr18_+_61639542 2.577 ENSMUST00000183083.1
ENSMUST00000183087.1
 Gm20748

predicted gene, 20748

chr3_-_88503187 2.522 ENSMUST00000120377.1
 Lmna
lamin A
chr6_+_124996681 2.373 ENSMUST00000032479.4
 Pianp
PILR alpha associated neural protein
chr14_-_79301623 2.321 ENSMUST00000022595.7
 Rgcc
regulator of cell cycle
chr15_-_97767798 2.195 ENSMUST00000129223.2
ENSMUST00000126854.2
ENSMUST00000135080.1
 Rapgef3


Rap guanine nucleotide exchange factor (GEF) 3


chr6_+_17463927 2.137 ENSMUST00000115442.1
 Met
met proto-oncogene
chr7_+_139834148 2.069 ENSMUST00000026548.7
 Gpr123
G protein-coupled receptor 123
chr15_-_97767644 1.945 ENSMUST00000128775.2
ENSMUST00000134885.2
 Rapgef3

Rap guanine nucleotide exchange factor (GEF) 3

chr7_-_142372210 1.883 ENSMUST00000084412.5
 Ifitm10
interferon induced transmembrane protein 10
chr17_-_24644933 1.871 ENSMUST00000019684.5
 Slc9a3r2
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 2
chr6_+_17463749 1.861 ENSMUST00000115443.1
 Met
met proto-oncogene
chr7_-_31042078 1.856 ENSMUST00000162116.1
ENSMUST00000159924.1
ENSMUST00000159753.1
ENSMUST00000160689.1
ENSMUST00000162733.1
ENSMUST00000162087.1
ENSMUST00000009831.7
 Fxyd5






FXYD domain-containing ion transport regulator 5






chr3_-_88503331 1.844 ENSMUST00000029699.6
 Lmna
lamin A
chr15_-_11037968 1.839 ENSMUST00000058007.5
 Rxfp3
relaxin family peptide receptor 3
chr6_+_7555053 1.750 ENSMUST00000090679.2
ENSMUST00000184986.1
 Tac1

tachykinin 1

chr1_+_165769392 1.743 ENSMUST00000040298.4
 Creg1
cellular repressor of E1A-stimulated genes 1
chr7_-_100964371 1.596 ENSMUST00000060174.4
 P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 103 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 4.6 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
1.1 4.4 GO:1904177 regulation of adipose tissue development(GO:1904177)
1.0 4.1 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.5 4.1 GO:0009181 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.2 3.8 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 3.6 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
0.2 2.5 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.6 2.3 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.2 2.1 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.1 2.1 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.1 1.9 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 1.9 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.6 1.8 GO:2000852 regulation of corticosterone secretion(GO:2000852)
0.1 1.8 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.5 1.6 GO:0030321 transepithelial chloride transport(GO:0030321)
0.2 1.6 GO:0015862 uridine transport(GO:0015862)
0.1 1.6 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.2 1.5 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.2 1.5 GO:0016081 synaptic vesicle docking(GO:0016081)
0.1 1.5 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 49 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 5.6 GO:1990796 photoreceptor cell terminal bouton(GO:1990796)
0.0 5.2 GO:0016323 basolateral plasma membrane(GO:0016323)
0.6 4.4 GO:0005638 lamin filament(GO:0005638)
0.1 4.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 2.8 GO:0005605 basal lamina(GO:0005605)
0.2 2.5 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 2.5 GO:0031985 Golgi cisterna(GO:0031985)
0.0 2.2 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 2.0 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 1.9 GO:0032420 stereocilium(GO:0032420)
0.0 1.6 GO:0005581 collagen trimer(GO:0005581)
0.3 1.5 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 1.5 GO:0097513 myosin II filament(GO:0097513)
0.2 1.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 1.2 GO:0002080 acrosomal membrane(GO:0002080)
0.2 1.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.1 GO:0042587 glycogen granule(GO:0042587)
0.0 1.1 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 1.1 GO:0030496 midbody(GO:0030496)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 80 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 4.6 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
0.2 4.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.2 4.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.5 4.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.5 4.1 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 3.6 GO:0002039 p53 binding(GO:0002039)
0.1 2.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.1 2.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 2.3 GO:0030295 protein kinase activator activity(GO:0030295)
0.1 1.9 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.9 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 1.7 GO:0010181 FMN binding(GO:0010181)
0.2 1.6 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 1.6 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 1.6 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.4 1.5 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.3 1.5 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 1.5 GO:0050544 arachidonic acid binding(GO:0050544)
0.1 1.5 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.5 1.4 GO:0004942 anaphylatoxin receptor activity(GO:0004942)