Motif ID: Klf1

Z-value: 1.055


Transcription factors associated with Klf1:

Gene SymbolEntrez IDGene Name
Klf1 ENSMUSG00000054191.7 Klf1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf1mm10_v2_chr8_+_84901928_84901992-0.078.1e-01Click!


Activity profile for motif Klf1.

activity profile for motif Klf1


Sorted Z-values histogram for motif Klf1

Sorted Z-values for motif Klf1



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_-_24680890 1.083 ENSMUST00000156453.2
 Cys1
cystin 1
chr8_+_123411424 1.004 ENSMUST00000071134.3
 Tubb3
tubulin, beta 3 class III
chr4_+_47208005 0.894 ENSMUST00000082303.6
ENSMUST00000102917.4
 Col15a1

collagen, type XV, alpha 1

chr6_-_72958465 0.806 ENSMUST00000114050.1
 Tmsb10
thymosin, beta 10
chr10_+_86779000 0.791 ENSMUST00000099396.2
 Nt5dc3
5'-nucleotidase domain containing 3
chr6_-_72958097 0.747 ENSMUST00000114049.1
 Tmsb10
thymosin, beta 10
chr6_+_5725639 0.721 ENSMUST00000115556.1
ENSMUST00000115555.1
ENSMUST00000115559.3
 Dync1i1


dynein cytoplasmic 1 intermediate chain 1


chr11_+_62575981 0.710 ENSMUST00000102643.1
 Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr10_-_80577285 0.697 ENSMUST00000038558.8
 Klf16
Kruppel-like factor 16
chr16_+_78930940 0.685 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
 Chodl


chondrolectin


chr2_+_32775769 0.661 ENSMUST00000066352.5
 Ptrh1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr2_-_162661075 0.641 ENSMUST00000109442.1
ENSMUST00000109445.2
ENSMUST00000109443.1
ENSMUST00000109441.1
 Ptprt



protein tyrosine phosphatase, receptor type, T



chr12_+_8771405 0.635 ENSMUST00000171158.1
 Sdc1
syndecan 1
chr12_+_105336922 0.635 ENSMUST00000180503.1
 2810011L19Rik
RIKEN cDNA 2810011L19 gene
chr2_+_121357714 0.631 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
 Ckmt1



creatine kinase, mitochondrial 1, ubiquitous



chr17_+_29490812 0.624 ENSMUST00000024811.6
 Pim1
proviral integration site 1
chr7_-_126704522 0.617 ENSMUST00000135087.1
 Coro1a
coronin, actin binding protein 1A
chr8_-_87472365 0.574 ENSMUST00000169693.1
 Cbln1
cerebellin 1 precursor protein
chr11_-_95587691 0.574 ENSMUST00000000122.6
 Ngfr
nerve growth factor receptor (TNFR superfamily, member 16)
chr18_+_86711520 0.570 ENSMUST00000122464.1
 Cbln2
cerebellin 2 precursor protein

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 476 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.4 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.1 1.3 GO:0045663 positive regulation of myoblast differentiation(GO:0045663)
0.0 1.3 GO:0032543 mitochondrial translation(GO:0032543)
0.2 1.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 1.1 GO:0032796 uropod organization(GO:0032796)
0.1 1.1 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.2 1.0 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 1.0 GO:0033280 response to vitamin D(GO:0033280)
0.1 1.0 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.0 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 1.0 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.1 0.9 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.1 0.9 GO:1904417 regulation of xenophagy(GO:1904415) positive regulation of xenophagy(GO:1904417)
0.1 0.9 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.1 0.9 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 0.9 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.9 GO:0009060 aerobic respiration(GO:0009060)
0.2 0.8 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.2 0.8 GO:0019659 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 184 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.7 GO:0045298 tubulin complex(GO:0045298)
0.1 1.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 1.4 GO:0071565 nBAF complex(GO:0071565)
0.1 1.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 1.2 GO:0070469 respiratory chain(GO:0070469)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.1 1.0 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.0 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 1.0 GO:0036064 ciliary basal body(GO:0036064)
0.1 0.9 GO:0008290 F-actin capping protein complex(GO:0008290)
0.1 0.8 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.1 0.8 GO:0070688 MLL5-L complex(GO:0070688)
0.1 0.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.8 GO:0031143 pseudopodium(GO:0031143)
0.0 0.8 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.8 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.2 0.7 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 290 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.5 GO:0003924 GTPase activity(GO:0003924)
0.1 1.8 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.7 GO:0051082 unfolded protein binding(GO:0051082)
0.2 1.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 1.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 1.2 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 1.1 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.2 1.0 GO:0045503 dynein light chain binding(GO:0045503)
0.1 1.0 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.1 1.0 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.1 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 1.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.0 1.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.2 0.9 GO:0004859 phospholipase inhibitor activity(GO:0004859) phospholipase A2 inhibitor activity(GO:0019834)
0.2 0.9 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.9 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.1 0.9 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)