Motif ID: Klf16_Sp8
Z-value: 1.184
Transcription factors associated with Klf16_Sp8:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Klf16 | ENSMUSG00000035397.8 | Klf16 |
| Sp8 | ENSMUSG00000048562.6 | Sp8 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Sp8 | mm10_v2_chr12_+_118846329_118846329 | 0.82 | 3.6e-04 | Click! |
| Klf16 | mm10_v2_chr10_-_80577285_80577327 | -0.46 | 1.0e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 1,021 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 6.3 | GO:0071499 | response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499) |
| 0.2 | 6.1 | GO:0048255 | mRNA stabilization(GO:0048255) |
| 0.9 | 5.6 | GO:0042160 | lipoprotein modification(GO:0042160) lipoprotein oxidation(GO:0042161) |
| 1.1 | 5.5 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 0.1 | 5.3 | GO:0043487 | regulation of RNA stability(GO:0043487) |
| 0.2 | 4.8 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.3 | 4.3 | GO:0021514 | ventral spinal cord interneuron differentiation(GO:0021514) |
| 0.4 | 4.2 | GO:1902459 | positive regulation of stem cell population maintenance(GO:1902459) |
| 1.0 | 4.1 | GO:1904451 | regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453) |
| 0.5 | 4.0 | GO:0038028 | insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) |
| 0.5 | 3.9 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 0.2 | 3.9 | GO:0048240 | sperm capacitation(GO:0048240) |
| 0.6 | 3.8 | GO:0010624 | regulation of Schwann cell proliferation(GO:0010624) |
| 0.2 | 3.8 | GO:0001516 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
| 0.1 | 3.8 | GO:1902668 | negative regulation of axon extension involved in axon guidance(GO:0048843) negative regulation of axon guidance(GO:1902668) |
| 1.2 | 3.7 | GO:0061743 | motor learning(GO:0061743) |
| 0.3 | 3.7 | GO:0032688 | negative regulation of interferon-beta production(GO:0032688) |
| 0.1 | 3.7 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.9 | 3.6 | GO:0007066 | female meiosis sister chromatid cohesion(GO:0007066) |
| 0.1 | 3.6 | GO:0034314 | Arp2/3 complex-mediated actin nucleation(GO:0034314) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 344 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 28.3 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 19.9 | GO:0005615 | extracellular space(GO:0005615) |
| 0.0 | 7.1 | GO:0031012 | extracellular matrix(GO:0031012) |
| 0.4 | 6.5 | GO:0002080 | acrosomal membrane(GO:0002080) |
| 0.1 | 6.1 | GO:0022626 | cytosolic ribosome(GO:0022626) |
| 0.0 | 6.1 | GO:0005759 | mitochondrial matrix(GO:0005759) |
| 0.3 | 6.0 | GO:0005605 | basal lamina(GO:0005605) |
| 0.8 | 5.8 | GO:0000796 | condensin complex(GO:0000796) |
| 0.5 | 5.6 | GO:0034362 | low-density lipoprotein particle(GO:0034362) |
| 0.3 | 4.7 | GO:0042581 | specific granule(GO:0042581) |
| 0.7 | 4.6 | GO:0033256 | I-kappaB/NF-kappaB complex(GO:0033256) |
| 0.4 | 4.6 | GO:0005885 | Arp2/3 protein complex(GO:0005885) |
| 0.0 | 4.4 | GO:0005743 | mitochondrial inner membrane(GO:0005743) |
| 0.1 | 4.3 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 1.0 | 4.1 | GO:1990795 | lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795) |
| 0.2 | 4.0 | GO:0097225 | sperm midpiece(GO:0097225) |
| 0.4 | 3.9 | GO:0071664 | catenin-TCF7L2 complex(GO:0071664) |
| 1.2 | 3.7 | GO:0000802 | transverse filament(GO:0000802) |
| 0.1 | 3.7 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
| 0.1 | 3.7 | GO:0070469 | respiratory chain(GO:0070469) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 568 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 9.1 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.0 | 8.2 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.0 | 7.7 | GO:0001077 | transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077) |
| 0.1 | 6.5 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.1 | 6.2 | GO:0031490 | chromatin DNA binding(GO:0031490) |
| 0.0 | 6.2 | GO:0003714 | transcription corepressor activity(GO:0003714) |
| 0.3 | 6.1 | GO:0043539 | protein serine/threonine kinase activator activity(GO:0043539) |
| 0.2 | 5.7 | GO:0019789 | SUMO transferase activity(GO:0019789) |
| 0.1 | 5.7 | GO:0005125 | cytokine activity(GO:0005125) |
| 0.1 | 5.3 | GO:0005179 | hormone activity(GO:0005179) |
| 0.0 | 5.1 | GO:0003729 | mRNA binding(GO:0003729) |
| 0.2 | 4.9 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
| 0.1 | 4.7 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 4.7 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.5 | 4.1 | GO:0017034 | Rap guanyl-nucleotide exchange factor activity(GO:0017034) |
| 0.5 | 4.1 | GO:0047499 | calcium-independent phospholipase A2 activity(GO:0047499) |
| 0.1 | 4.1 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.3 | 3.9 | GO:0099602 | acetylcholine receptor regulator activity(GO:0030548) neurotransmitter receptor regulator activity(GO:0099602) |
| 0.1 | 3.9 | GO:0050840 | extracellular matrix binding(GO:0050840) |
| 0.1 | 3.8 | GO:0005484 | SNAP receptor activity(GO:0005484) |
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