Motif ID: Klf3

Z-value: 0.378


Transcription factors associated with Klf3:

Gene SymbolEntrez IDGene Name
Klf3 ENSMUSG00000029178.8 Klf3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf3mm10_v2_chr5_+_64803513_64803530-0.661.1e-02Click!


Activity profile for motif Klf3.

activity profile for motif Klf3


Sorted Z-values histogram for motif Klf3

Sorted Z-values for motif Klf3



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_-_103827922 0.845 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chr1_+_72824482 0.446 ENSMUST00000047328.4
 Igfbp2
insulin-like growth factor binding protein 2
chr11_+_68968107 0.424 ENSMUST00000102606.3
ENSMUST00000018884.5
 Slc25a35

solute carrier family 25, member 35

chr12_+_87026286 0.389 ENSMUST00000146292.1
 Tmem63c
transmembrane protein 63c
chrX_-_102251852 0.382 ENSMUST00000101336.3
ENSMUST00000136277.1
 Cited1

Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1

chr12_+_87026564 0.372 ENSMUST00000110187.1
ENSMUST00000156162.1
 Tmem63c

transmembrane protein 63c

chrX_-_102252154 0.331 ENSMUST00000050551.3
 Cited1
Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1
chr3_+_135438722 0.229 ENSMUST00000166033.1
 Ube2d3
ubiquitin-conjugating enzyme E2D 3
chr3_-_89089955 0.167 ENSMUST00000166687.1
 Rusc1
RUN and SH3 domain containing 1
chr7_-_4149781 0.149 ENSMUST00000058358.6
 Leng9
leukocyte receptor cluster (LRC) member 9
chr3_+_90079540 0.146 ENSMUST00000029549.9
ENSMUST00000118566.1
ENSMUST00000119158.1
 Tpm3


tropomyosin 3, gamma


chr11_+_99041237 0.146 ENSMUST00000017637.6
 Igfbp4
insulin-like growth factor binding protein 4
chrX_+_7884321 0.145 ENSMUST00000096514.3
ENSMUST00000123277.1
 Slc35a2

solute carrier family 35 (UDP-galactose transporter), member A2

chr11_-_97500340 0.125 ENSMUST00000056955.1
 4933428G20Rik
RIKEN cDNA 4933428G20 gene
chr19_+_10041548 0.113 ENSMUST00000115995.2
 Fads3
fatty acid desaturase 3
chr3_+_89266552 0.100 ENSMUST00000040824.1
 Dpm3
dolichyl-phosphate mannosyltransferase polypeptide 3
chr3_+_90080442 0.086 ENSMUST00000127955.1
 Tpm3
tropomyosin 3, gamma
chr7_+_82337218 0.086 ENSMUST00000173828.1
 Adamtsl3
ADAMTS-like 3
chr9_-_108305941 0.066 ENSMUST00000044725.7
 Tcta
T cell leukemia translocation altered gene
chr13_-_74292297 0.062 ENSMUST00000109640.1
ENSMUST00000022059.7
 Ahrr

aryl-hydrocarbon receptor repressor

chr1_+_107511489 0.060 ENSMUST00000064916.2
 Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr1_+_86064619 0.057 ENSMUST00000027432.8
 Psmd1
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr1_+_131867224 0.034 ENSMUST00000112386.1
ENSMUST00000027693.7
 Rab7l1

RAB7, member RAS oncogene family-like 1

chr5_+_137630116 0.028 ENSMUST00000175968.1
 Lrch4
leucine-rich repeats and calponin homology (CH) domain containing 4
chr5_+_124541296 0.019 ENSMUST00000124529.1
 Tmed2
transmembrane emp24 domain trafficking protein 2
chr3_-_89960562 0.012 ENSMUST00000069805.7
 Atp8b2
ATPase, class I, type 8B, member 2
chr1_+_107511416 0.011 ENSMUST00000009356.4
 Serpinb2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr15_-_102722150 0.008 ENSMUST00000023818.3
 Calcoco1
calcium binding and coiled coil domain 1
chrX_-_74246534 0.005 ENSMUST00000101454.2
ENSMUST00000033699.6
 Flna

filamin, alpha

chr7_-_17027853 0.002 ENSMUST00000003183.5
 Ppp5c
protein phosphatase 5, catalytic subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0071105 response to interleukin-9(GO:0071104) response to interleukin-11(GO:0071105)
0.0 0.6 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.0 0.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.1 0.7 GO:0050693 LBD domain binding(GO:0050693)
0.1 0.6 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.8 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.1 GO:0016215 acyl-CoA desaturase activity(GO:0016215)