Motif ID: Klf6_Patz1

Z-value: 1.489

Transcription factors associated with Klf6_Patz1:

Gene SymbolEntrez IDGene Name
Klf6 ENSMUSG00000000078.6 Klf6
Patz1 ENSMUSG00000020453.11 Patz1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Patz1mm10_v2_chr11_+_3290300_32904570.823.8e-04Click!
Klf6mm10_v2_chr13_+_5861489_58615010.461.0e-01Click!


Activity profile for motif Klf6_Patz1.

activity profile for motif Klf6_Patz1


Sorted Z-values histogram for motif Klf6_Patz1

Sorted Z-values for motif Klf6_Patz1



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf6_Patz1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_125490688 6.766 ENSMUST00000030676.7
 Grik3
glutamate receptor, ionotropic, kainate 3
chr11_-_95514570 6.160 ENSMUST00000058866.7
 Nxph3
neurexophilin 3
chr10_-_127534540 4.778 ENSMUST00000095266.2
 Nxph4
neurexophilin 4
chr11_-_95587691 4.608 ENSMUST00000000122.6
 Ngfr
nerve growth factor receptor (TNFR superfamily, member 16)
chr11_+_119942763 3.954 ENSMUST00000026436.3
ENSMUST00000106231.1
ENSMUST00000075180.5
ENSMUST00000103021.3
ENSMUST00000106233.1
 Baiap2




brain-specific angiogenesis inhibitor 1-associated protein 2




chr7_+_36698002 3.864 ENSMUST00000021641.6
 Tshz3
teashirt zinc finger family member 3
chr1_-_172057573 3.447 ENSMUST00000059794.3
 Nhlh1
nescient helix loop helix 1
chr13_-_56252163 3.267 ENSMUST00000058475.4
 Neurog1
neurogenin 1
chr3_+_103575231 3.122 ENSMUST00000121834.1
 Syt6
synaptotagmin VI
chr3_+_103576081 3.122 ENSMUST00000183637.1
ENSMUST00000117221.2
ENSMUST00000118117.1
ENSMUST00000118563.2
 Syt6



synaptotagmin VI



chr11_-_63922257 3.058 ENSMUST00000094103.3
 Hs3st3b1
heparan sulfate (glucosamine) 3-O-sulfotransferase 3B1
chr7_+_123982799 3.035 ENSMUST00000106437.1
 Hs3st4
heparan sulfate (glucosamine) 3-O-sulfotransferase 4
chr3_+_121953213 2.983 ENSMUST00000037958.7
ENSMUST00000128366.1
 Arhgap29

Rho GTPase activating protein 29

chr15_-_60824942 2.865 ENSMUST00000100635.3
 Fam84b
family with sequence similarity 84, member B
chr1_-_106714217 2.791 ENSMUST00000112751.1
 Bcl2
B cell leukemia/lymphoma 2
chr15_-_76521902 2.773 ENSMUST00000164703.1
ENSMUST00000096365.3
 Scrt1

scratch homolog 1, zinc finger protein (Drosophila)

chr14_-_39472825 2.675 ENSMUST00000168810.2
ENSMUST00000173780.1
ENSMUST00000166968.2
 Nrg3


neuregulin 3


chr9_-_24503127 2.673 ENSMUST00000142064.1
ENSMUST00000170356.1
 Dpy19l1

dpy-19-like 1 (C. elegans)

chr1_+_153652943 2.647 ENSMUST00000041776.5
 Rgs8
regulator of G-protein signaling 8
chr7_-_34812677 2.561 ENSMUST00000078686.6
 Chst8
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 661 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.9 8.8 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.7 7.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 7.2 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.9 5.2 GO:0060022 hard palate development(GO:0060022)
1.6 4.8 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902) negative regulation of membrane depolarization(GO:1904180)
0.3 4.3 GO:0051764 actin crosslink formation(GO:0051764)
0.3 4.3 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
1.3 3.9 GO:0050975 sensory perception of touch(GO:0050975)
0.2 3.9 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.3 3.8 GO:0007252 I-kappaB phosphorylation(GO:0007252)
1.2 3.7 GO:0018103 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.6 3.7 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.4 3.5 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.4 3.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
1.1 3.2 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.4 3.1 GO:0006477 protein sulfation(GO:0006477)
0.3 3.0 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.1 3.0 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.3 2.9 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.9 2.8 GO:0046671 regulation of cellular pH reduction(GO:0032847) negative regulation of retinal cell programmed cell death(GO:0046671)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 244 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.7 GO:0043197 dendritic spine(GO:0043197)
0.3 8.7 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 7.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 7.2 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 6.5 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 6.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 5.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 4.7 GO:0055037 recycling endosome(GO:0055037)
0.2 3.9 GO:0000145 exocyst(GO:0000145)
0.3 3.8 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 3.7 GO:0005871 kinesin complex(GO:0005871)
0.0 3.7 GO:0098794 postsynapse(GO:0098794)
0.1 3.4 GO:0071565 nBAF complex(GO:0071565)
0.0 3.3 GO:0016605 PML body(GO:0016605)
0.1 3.0 GO:1990391 DNA repair complex(GO:1990391)
0.2 2.9 GO:0031209 SCAR complex(GO:0031209)
0.1 2.9 GO:0043198 dendritic shaft(GO:0043198)
0.0 2.9 GO:0043204 perikaryon(GO:0043204)
0.7 2.8 GO:0060187 cell pole(GO:0060187)
0.1 2.7 GO:0005637 nuclear inner membrane(GO:0005637)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 345 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 9.9 GO:0030165 PDZ domain binding(GO:0030165)
0.2 8.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 7.0 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.2 6.4 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0 6.4 GO:0061659 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
1.2 6.2 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2 5.9 GO:0070064 proline-rich region binding(GO:0070064)
0.0 5.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.2 5.3 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.5 4.8 GO:0048406 nerve growth factor binding(GO:0048406)
0.1 4.5 GO:0045499 chemorepellent activity(GO:0045499)
0.5 4.3 GO:0001618 virus receptor activity(GO:0001618)
0.5 4.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 4.2 GO:0003777 microtubule motor activity(GO:0003777)
0.1 4.0 GO:0035496 UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062)
0.6 3.9 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.6 3.5 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.2 3.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 3.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.4 3.0 GO:0051434 BH3 domain binding(GO:0051434)