Motif ID: Klf7

Z-value: 0.724


Transcription factors associated with Klf7:

Gene SymbolEntrez IDGene Name
Klf7 ENSMUSG00000025959.7 Klf7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf7mm10_v2_chr1_-_64121389_64121452-0.273.5e-01Click!


Activity profile for motif Klf7.

activity profile for motif Klf7


Sorted Z-values histogram for motif Klf7

Sorted Z-values for motif Klf7



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf7

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrY_+_897782 4.444 ENSMUST00000055032.7
 Kdm5d
lysine (K)-specific demethylase 5D
chr12_-_4592927 2.920 ENSMUST00000170816.1
 Gm3625
predicted gene 3625
chr3_+_106721893 0.908 ENSMUST00000106736.2
ENSMUST00000154973.1
ENSMUST00000131330.1
ENSMUST00000150513.1
 Lrif1



ligand dependent nuclear receptor interacting factor 1



chr15_-_89196457 0.715 ENSMUST00000078953.7
 Dennd6b
DENN/MADD domain containing 6B
chr3_+_106721672 0.694 ENSMUST00000098750.2
ENSMUST00000130105.1
 Lrif1

ligand dependent nuclear receptor interacting factor 1

chr2_+_119047116 0.591 ENSMUST00000152380.1
ENSMUST00000099542.2
 Casc5

cancer susceptibility candidate 5

chr2_+_158375638 0.590 ENSMUST00000109488.1
 Snhg11
small nucleolar RNA host gene 11
chr2_+_119047129 0.518 ENSMUST00000153300.1
ENSMUST00000028799.5
 Casc5

cancer susceptibility candidate 5

chr1_-_138847579 0.507 ENSMUST00000093486.3
ENSMUST00000046870.6
 Lhx9

LIM homeobox protein 9

chr8_+_70152754 0.462 ENSMUST00000072500.6
ENSMUST00000164040.1
ENSMUST00000110146.2
ENSMUST00000110143.1
ENSMUST00000110141.2
ENSMUST00000110140.1
 2310045N01Rik

Mef2b



RIKEN cDNA 2310045N01 gene

myocyte enhancer factor 2B



chr6_-_88875035 0.434 ENSMUST00000145944.1
 Podxl2
podocalyxin-like 2
chr4_+_107830958 0.387 ENSMUST00000106731.2
 Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr5_+_140607334 0.381 ENSMUST00000031555.1
 Lfng
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr1_-_23383149 0.350 ENSMUST00000027343.5
 Ogfrl1
opioid growth factor receptor-like 1
chr11_+_78176711 0.329 ENSMUST00000098545.5
 Tlcd1
TLC domain containing 1
chr6_-_88874597 0.308 ENSMUST00000061262.4
ENSMUST00000140455.1
ENSMUST00000145780.1
 Podxl2


podocalyxin-like 2


chr11_-_78176619 0.290 ENSMUST00000148154.2
ENSMUST00000017549.6
 Nek8

NIMA (never in mitosis gene a)-related expressed kinase 8

chr5_-_34187670 0.283 ENSMUST00000042701.6
ENSMUST00000119171.1
 Mxd4

Max dimerization protein 4

chr9_-_45936049 0.253 ENSMUST00000034590.2
 Tagln
transgelin
chr5_+_137778849 0.251 ENSMUST00000126126.1
ENSMUST00000031739.4
 Ppp1r35

protein phosphatase 1, regulatory subunit 35

chr1_-_57406443 0.247 ENSMUST00000160837.1
ENSMUST00000161780.1
 Tyw5

tRNA-yW synthesizing protein 5

chr10_+_86705811 0.242 ENSMUST00000061458.7
ENSMUST00000075632.6
 BC030307

cDNA sequence BC030307

chr9_+_104002546 0.241 ENSMUST00000035167.8
ENSMUST00000117054.1
 Nphp3

nephronophthisis 3 (adolescent)

chr2_-_32694120 0.241 ENSMUST00000028148.4
 Fpgs
folylpolyglutamyl synthetase
chr11_-_40733373 0.233 ENSMUST00000020579.8
 Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr4_+_127126034 0.225 ENSMUST00000094712.4
 Gm12942
predicted gene 12942
chr6_-_39118211 0.214 ENSMUST00000038398.6
 Parp12
poly (ADP-ribose) polymerase family, member 12
chr4_-_87230435 0.211 ENSMUST00000107157.2
 Slc24a2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr6_+_52713729 0.204 ENSMUST00000080723.4
ENSMUST00000149588.1
 Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr13_+_96542727 0.185 ENSMUST00000077672.4
ENSMUST00000109444.2
 Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr5_-_134456702 0.183 ENSMUST00000073161.5
ENSMUST00000171794.2
ENSMUST00000111245.2
ENSMUST00000100654.3
ENSMUST00000167084.2
ENSMUST00000100652.3
ENSMUST00000100650.3
ENSMUST00000074114.5
 Gtf2ird1







general transcription factor II I repeat domain-containing 1







chr5_+_33658123 0.177 ENSMUST00000074849.6
ENSMUST00000079534.4
 Tacc3

transforming, acidic coiled-coil containing protein 3

chr2_-_156180135 0.175 ENSMUST00000126992.1
ENSMUST00000146288.1
ENSMUST00000029149.6
ENSMUST00000109587.2
ENSMUST00000109584.1
 Rbm39




RNA binding motif protein 39




chr12_+_118846329 0.172 ENSMUST00000063918.2
 Sp8
trans-acting transcription factor 8
chr8_+_3621529 0.159 ENSMUST00000156380.2
 Pet100
PET100 homolog (S. cerevisiae)
chr7_+_58658181 0.158 ENSMUST00000168747.1
 Atp10a
ATPase, class V, type 10A
chr7_-_19404082 0.158 ENSMUST00000108458.3
 Klc3
kinesin light chain 3
chr2_-_156312470 0.156 ENSMUST00000079125.6
 Scand1
SCAN domain-containing 1
chr5_-_115348953 0.155 ENSMUST00000040154.8
 Cox6a1
cytochrome c oxidase subunit VIa polypeptide 1
chr1_-_120121030 0.154 ENSMUST00000027634.6
 Dbi
diazepam binding inhibitor
chr8_-_22476809 0.148 ENSMUST00000163774.1
ENSMUST00000033935.8
 Smim19

small integral membrane protein 19

chr19_-_8723356 0.143 ENSMUST00000170157.1
 Slc3a2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr1_-_172082757 0.140 ENSMUST00000003550.4
 Ncstn
nicastrin
chr12_+_49383007 0.131 ENSMUST00000021333.3
 Foxg1
forkhead box G1
chr1_+_163929765 0.129 ENSMUST00000027876.4
ENSMUST00000170359.1
 Scyl3

SCY1-like 3 (S. cerevisiae)

chr5_-_3596071 0.127 ENSMUST00000121877.1
 Rbm48
RNA binding motif protein 48
chr6_+_125039760 0.127 ENSMUST00000140131.1
ENSMUST00000032480.7
 Ing4

inhibitor of growth family, member 4

chr11_+_68432112 0.126 ENSMUST00000021283.7
 Pik3r5
phosphoinositide-3-kinase, regulatory subunit 5, p101
chr7_+_45154644 0.117 ENSMUST00000153973.1
 Pih1d1
PIH1 domain containing 1
chr19_+_5637475 0.114 ENSMUST00000025867.5
 Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr7_-_45154519 0.114 ENSMUST00000007977.7
ENSMUST00000107815.1
 Aldh16a1

aldehyde dehydrogenase 16 family, member A1

chr1_+_120121161 0.114 ENSMUST00000027637.6
ENSMUST00000112644.2
ENSMUST00000056038.8
 3110009E18Rik


RIKEN cDNA 3110009E18 gene


chr19_+_8723478 0.111 ENSMUST00000180819.1
ENSMUST00000181422.1
 Snhg1

small nucleolar RNA host gene (non-protein coding) 1

chr17_+_24488773 0.107 ENSMUST00000024958.7
 Caskin1
CASK interacting protein 1
chr12_+_49382791 0.107 ENSMUST00000179669.1
 Foxg1
forkhead box G1
chr5_+_115631902 0.099 ENSMUST00000031492.8
 Rab35
RAB35, member RAS oncogene family
chr9_-_32344237 0.097 ENSMUST00000034533.5
 Kcnj5
potassium inwardly-rectifying channel, subfamily J, member 5
chr6_+_52714219 0.094 ENSMUST00000138040.1
ENSMUST00000129660.1
 Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr7_-_116198487 0.093 ENSMUST00000181981.1
 Plekha7
pleckstrin homology domain containing, family A member 7
chr2_+_130424321 0.089 ENSMUST00000128994.1
ENSMUST00000028900.9
 Vps16

vacuolar protein sorting 16 (yeast)

chr2_+_156312589 0.081 ENSMUST00000073942.5
ENSMUST00000109580.1
 Cnbd2

cyclic nucleotide binding domain containing 2

chr8_+_71367210 0.077 ENSMUST00000019169.7
 Use1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr8_+_3500451 0.073 ENSMUST00000004683.6
ENSMUST00000160338.1
 Mcoln1

mucolipin 1

chr13_+_21722057 0.070 ENSMUST00000110476.3
 Hist1h2bm
histone cluster 1, H2bm
chr4_+_63558748 0.066 ENSMUST00000077709.4
 6330416G13Rik
RIKEN cDNA 6330416G13 gene
chr7_-_28766469 0.064 ENSMUST00000085851.5
ENSMUST00000032815.4
 Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr15_-_50889043 0.061 ENSMUST00000183997.1
ENSMUST00000183757.1
 Trps1

trichorhinophalangeal syndrome I (human)

chr1_-_58445369 0.060 ENSMUST00000114345.2
ENSMUST00000117069.1
ENSMUST00000114348.1
ENSMUST00000081677.5
 Ppil3



peptidylprolyl isomerase (cyclophilin)-like 3



chr2_+_181497165 0.055 ENSMUST00000149163.1
ENSMUST00000000844.8
ENSMUST00000184849.1
ENSMUST00000108800.1
ENSMUST00000069712.2
 Tpd52l2




tumor protein D52-like 2




chr9_-_88438898 0.054 ENSMUST00000173011.1
ENSMUST00000174806.1
 Snx14

sorting nexin 14

chr11_-_110251736 0.052 ENSMUST00000044003.7
 Abca6
ATP-binding cassette, sub-family A (ABC1), member 6
chr10_-_86705485 0.049 ENSMUST00000020238.7
 Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr1_-_120120937 0.040 ENSMUST00000151708.1
 Dbi
diazepam binding inhibitor
chr2_+_172550991 0.040 ENSMUST00000170744.1
 Tfap2c
transcription factor AP-2, gamma
chr18_+_67133713 0.039 ENSMUST00000076605.7
 Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr7_-_101011976 0.034 ENSMUST00000178340.1
ENSMUST00000037540.3
 P2ry2

purinergic receptor P2Y, G-protein coupled 2

chr10_+_79682169 0.027 ENSMUST00000020550.5
 Cdc34
cell division cycle 34
chr11_-_101302206 0.027 ENSMUST00000140706.1
ENSMUST00000170502.1
ENSMUST00000172233.1
ENSMUST00000130916.1
 Becn1



beclin 1, autophagy related



chr1_+_171329015 0.024 ENSMUST00000111300.1
 Dedd
death effector domain-containing
chr10_+_127677064 0.024 ENSMUST00000118612.1
ENSMUST00000048099.4
 Tmem194

transmembrane protein 194

chr8_-_84966008 0.022 ENSMUST00000109738.3
ENSMUST00000065049.8
ENSMUST00000128972.1
 Rnaseh2a


ribonuclease H2, large subunit


chr15_-_102722120 0.020 ENSMUST00000171838.1
 Calcoco1
calcium binding and coiled coil domain 1
chr11_-_70654624 0.019 ENSMUST00000018437.2
 Pfn1
profilin 1
chr8_+_84901928 0.018 ENSMUST00000067060.7
 Klf1
Kruppel-like factor 1 (erythroid)
chr15_+_99074968 0.015 ENSMUST00000039665.6
 Troap
trophinin associated protein
chr8_+_71922810 0.012 ENSMUST00000119003.1
 Zfp617
zinc finger protein 617
chr1_+_167689108 0.011 ENSMUST00000111377.1
 Lmx1a
LIM homeobox transcription factor 1 alpha
chr8_+_105860634 0.010 ENSMUST00000008594.7
 Nutf2
nuclear transport factor 2
chr7_+_45154297 0.009 ENSMUST00000107813.1
ENSMUST00000125953.1
ENSMUST00000085375.5
ENSMUST00000144597.1
 Pih1d1



PIH1 domain containing 1



chr5_+_3596066 0.007 ENSMUST00000006061.6
ENSMUST00000121291.1
ENSMUST00000142516.1
 Pex1


peroxisomal biogenesis factor 1


chr5_-_136135989 0.006 ENSMUST00000150406.1
ENSMUST00000006301.4
 Lrwd1

leucine-rich repeats and WD repeat domain containing 1

chr7_+_28766747 0.004 ENSMUST00000170068.1
ENSMUST00000072965.4
 Sirt2

sirtuin 2

chr7_-_133776772 0.004 ENSMUST00000033290.5
 Dhx32
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr15_-_102722150 0.003 ENSMUST00000023818.3
 Calcoco1
calcium binding and coiled coil domain 1
chr7_+_28350652 0.002 ENSMUST00000082134.4
 Rps16
ribosomal protein S16
chr11_-_106779483 0.001 ENSMUST00000021060.5
 Polg2
polymerase (DNA directed), gamma 2, accessory subunit

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 4.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.5 GO:0035262 gonad morphogenesis(GO:0035262)
0.1 0.2 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.1 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.2 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.2 GO:0021852 pyramidal neuron migration(GO:0021852)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 1.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.0 0.7 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.4 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.2 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.2 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.0 0.3 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.1 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.0 0.1 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.1 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.1 GO:0045218 zonula adherens maintenance(GO:0045218)
0.0 0.2 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.0 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.0 0.2 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0097651 phosphatidylinositol 3-kinase complex, class I(GO:0097651)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0097255 R2TP complex(GO:0097255)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.7 GO:0055037 recycling endosome(GO:0055037)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 1.0 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.4 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.4 GO:0038025 reelin receptor activity(GO:0038025)
0.0 0.2 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.2 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.2 GO:0097001 sphingolipid transporter activity(GO:0046624) ceramide binding(GO:0097001)
0.0 1.6 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.1 GO:0019145 aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.0 GO:0050827 toxin receptor binding(GO:0050827)
0.0 0.2 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.0 GO:0031686 A1 adenosine receptor binding(GO:0031686)