Motif ID: Lhx3

Z-value: 0.789


Transcription factors associated with Lhx3:

Gene SymbolEntrez IDGene Name
Lhx3 ENSMUSG00000026934.9 Lhx3



Activity profile for motif Lhx3.

activity profile for motif Lhx3


Sorted Z-values histogram for motif Lhx3

Sorted Z-values for motif Lhx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Lhx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 90 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_49608030 2.189 ENSMUST00000021822.5
 Ogn
osteoglycin
chr7_-_103827922 1.290 ENSMUST00000023934.6
ENSMUST00000153218.1
 Hbb-bs

hemoglobin, beta adult s chain

chrM_+_9452 1.161 ENSMUST00000082411.1
 mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr7_-_45103747 1.118 ENSMUST00000003512.7
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr4_+_145585166 1.081 ENSMUST00000105739.1
ENSMUST00000119718.1
 Gm13212

predicted gene 13212

chr10_+_75037291 1.019 ENSMUST00000139384.1
 Rab36
RAB36, member RAS oncogene family
chr3_+_151437887 0.998 ENSMUST00000046977.7
 Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr8_-_21906412 0.989 ENSMUST00000051965.4
 Defb11
defensin beta 11
chr3_+_41742615 0.828 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
 D3Ertd751e





DNA segment, Chr 3, ERATO Doi 751, expressed





chr17_-_48432723 0.819 ENSMUST00000046549.3
 Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr3_-_41742471 0.798 ENSMUST00000026866.8
 Sclt1
sodium channel and clathrin linker 1
chr4_+_147132038 0.797 ENSMUST00000084149.3
 Gm13139
predicted gene 13139
chr11_+_109543694 0.784 ENSMUST00000106696.1
 Arsg
arylsulfatase G
chrM_-_14060 0.746 ENSMUST00000082419.1
 mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr2_+_36230426 0.682 ENSMUST00000062069.5
 Ptgs1
prostaglandin-endoperoxide synthase 1
chr2_+_125136692 0.638 ENSMUST00000099452.2
 Ctxn2
cortexin 2
chr4_+_136143497 0.631 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chrM_+_9870 0.620 ENSMUST00000084013.1
 mt-Nd4l
mitochondrially encoded NADH dehydrogenase 4L
chr10_-_6980376 0.615 ENSMUST00000105617.1
 Ipcef1
interaction protein for cytohesin exchange factors 1
chr1_+_153665587 0.605 ENSMUST00000147700.1
 Rgs8
regulator of G-protein signaling 8

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 1.6 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 1.2 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.1 0.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.8 GO:0080111 DNA demethylation(GO:0080111)
0.2 0.7 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.6 GO:0033762 response to glucagon(GO:0033762)
0.0 0.6 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.0 0.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.6 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.2 0.5 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.1 0.5 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
0.1 0.5 GO:0009235 cobalamin metabolic process(GO:0009235)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.0 0.4 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.4 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.4 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.1 0.3 GO:0090258 negative regulation of mitochondrial fission(GO:0090258)
0.1 0.3 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.3 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.3 GO:0010459 negative regulation of heart rate(GO:0010459)

Gene overrepresentation in cellular_component category:

Showing 1 to 10 of 10 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 2.5 GO:0070469 respiratory chain(GO:0070469)
0.0 1.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.3 1.3 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.8 GO:0071439 clathrin complex(GO:0071439)
0.1 0.6 GO:0045275 respiratory chain complex III(GO:0045275)
0.1 0.5 GO:0042629 mast cell granule(GO:0042629)
0.0 0.3 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 2.2 GO:0008083 growth factor activity(GO:0008083)
0.0 1.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 1.3 GO:0031721 haptoglobin binding(GO:0031720) hemoglobin alpha binding(GO:0031721)
0.4 1.1 GO:0019770 IgG receptor activity(GO:0019770)
0.1 0.8 GO:0018741 alkyl sulfatase activity(GO:0018741) endosulfan hemisulfate sulfatase activity(GO:0034889) endosulfan sulfate hydrolase activity(GO:0034902)
0.0 0.8 GO:0016814 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines(GO:0016814)
0.0 0.8 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.7 GO:0004601 peroxidase activity(GO:0004601)
0.1 0.6 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.6 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.3 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.1 0.3 GO:0043125 ErbB-3 class receptor binding(GO:0043125)
0.1 0.3 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 0.3 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)