Motif ID: Mafa

Z-value: 1.190


Transcription factors associated with Mafa:

Gene SymbolEntrez IDGene Name
Mafa ENSMUSG00000047591.4 Mafa

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafamm10_v2_chr15_-_75747922_757479220.185.4e-01Click!


Activity profile for motif Mafa.

activity profile for motif Mafa


Sorted Z-values histogram for motif Mafa

Sorted Z-values for motif Mafa



Network of associatons between targets according to the STRING database.



First level regulatory network of Mafa

PNG image of the network

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Top targets:


Showing 1 to 20 of 84 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_+_102254739 3.862 ENSMUST00000106907.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr4_+_102254993 3.126 ENSMUST00000106908.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr4_+_42035113 2.036 ENSMUST00000098127.1
 Gm10597
predicted gene 10597
chr11_-_66525964 1.982 ENSMUST00000066679.6
 Shisa6
shisa homolog 6 (Xenopus laevis)
chr4_+_21931291 1.790 ENSMUST00000029908.7
 Faxc
failed axon connections homolog (Drosophila)
chr9_-_98032983 1.748 ENSMUST00000162295.1
 Clstn2
calsyntenin 2
chr9_-_48835932 1.722 ENSMUST00000093852.3
 Zbtb16
zinc finger and BTB domain containing 16
chr1_-_169747634 1.700 ENSMUST00000027991.5
ENSMUST00000111357.1
 Rgs4

regulator of G-protein signaling 4

chrX_+_104482774 1.630 ENSMUST00000087867.5
 Uprt
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chr12_-_75177325 1.606 ENSMUST00000042299.2
 Kcnh5
potassium voltage-gated channel, subfamily H (eag-related), member 5
chrX_-_73869804 1.556 ENSMUST00000066576.5
ENSMUST00000114430.1
 L1cam

L1 cell adhesion molecule

chr4_-_35845204 1.541 ENSMUST00000164772.1
ENSMUST00000065173.2
 Lingo2

leucine rich repeat and Ig domain containing 2

chr14_+_119138415 1.493 ENSMUST00000065904.3
 Hs6st3
heparan sulfate 6-O-sulfotransferase 3
chr7_-_67759735 1.449 ENSMUST00000074233.4
ENSMUST00000051389.8
 Synm

synemin, intermediate filament protein

chr9_-_51077064 1.347 ENSMUST00000098782.3
 Layn
layilin
chr11_-_107337556 1.157 ENSMUST00000040380.6
 Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr8_+_105373265 1.125 ENSMUST00000160650.1
 Plekhg4
pleckstrin homology domain containing, family G (with RhoGef domain) member 4
chr16_-_74411776 1.107 ENSMUST00000116586.2
 Robo2
roundabout homolog 2 (Drosophila)
chr9_-_45906837 1.000 ENSMUST00000161203.1
ENSMUST00000058720.5
ENSMUST00000160699.1
 Rnf214


ring finger protein 214


chr17_-_72603709 0.983 ENSMUST00000086639.4
 Alk
anaplastic lymphoma kinase

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 7.0 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 3.8 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.2 2.7 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.7 2.0 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.3 1.7 GO:0048133 NK T cell differentiation(GO:0001865) germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) regulation of NK T cell differentiation(GO:0051136) positive regulation of NK T cell differentiation(GO:0051138) germline stem cell asymmetric division(GO:0098728)
0.0 1.7 GO:0090630 activation of GTPase activity(GO:0090630)
0.5 1.6 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.3 1.6 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 1.6 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.2 1.5 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 1.4 GO:0003009 skeletal muscle contraction(GO:0003009)
0.0 1.4 GO:0045744 negative regulation of G-protein coupled receptor protein signaling pathway(GO:0045744)
0.0 0.9 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.1 0.8 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.8 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 0.8 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.2 0.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.7 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.7 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.1 0.7 GO:0035507 regulation of myosin-light-chain-phosphatase activity(GO:0035507)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 7.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.7 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 2.0 GO:0030673 axolemma(GO:0030673)
0.0 1.8 GO:0016605 PML body(GO:0016605)
0.0 1.6 GO:0044295 axonal growth cone(GO:0044295)
0.2 1.4 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 0.8 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.7 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.6 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.6 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.0 0.6 GO:0001527 microfibril(GO:0001527)
0.0 0.6 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.1 GO:0008290 F-actin capping protein complex(GO:0008290)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.0 GO:0030552 cAMP binding(GO:0030552)
0.2 2.0 GO:0008046 axon guidance receptor activity(GO:0008046)
0.2 1.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.3 1.6 GO:0004849 uridine kinase activity(GO:0004849)
0.3 1.6 GO:0033691 sialic acid binding(GO:0033691)
0.3 1.6 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.0 1.5 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.1 1.4 GO:0019215 intermediate filament binding(GO:0019215)
0.1 1.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 1.0 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.0 0.9 GO:0015297 antiporter activity(GO:0015297)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.2 0.7 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.2 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.7 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.5 GO:0004065 arylsulfatase activity(GO:0004065)