Motif ID: Mafb

Z-value: 0.649


Transcription factors associated with Mafb:

Gene SymbolEntrez IDGene Name
Mafb ENSMUSG00000074622.3 Mafb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafbmm10_v2_chr2_-_160367057_160367073-0.087.7e-01Click!


Activity profile for motif Mafb.

activity profile for motif Mafb


Sorted Z-values histogram for motif Mafb

Sorted Z-values for motif Mafb



Network of associatons between targets according to the STRING database.



First level regulatory network of Mafb

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr18_+_65873478 1.040 ENSMUST00000025395.8
ENSMUST00000173530.1
 Grp

gastrin releasing peptide

chr9_-_48911067 0.987 ENSMUST00000003826.7
 Htr3a
5-hydroxytryptamine (serotonin) receptor 3A
chr7_+_141029131 0.975 ENSMUST00000170892.1
 Gm17387
predicted gene, 17387
chr4_-_136886187 0.716 ENSMUST00000046384.8
 C1qb
complement component 1, q subcomponent, beta polypeptide
chr17_+_22689771 0.609 ENSMUST00000055305.8
 Gm9805
predicted gene 9805
chr2_+_136052180 0.608 ENSMUST00000144403.1
 Lamp5
lysosomal-associated membrane protein family, member 5
chr11_+_82101836 0.598 ENSMUST00000000194.3
 Ccl12
chemokine (C-C motif) ligand 12
chr13_-_23710714 0.594 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
 Hfe


hemochromatosis


chr10_+_70204675 0.585 ENSMUST00000020090.1
 2310015B20Rik
RIKEN cDNA 2310015B20 gene
chr9_+_45403138 0.487 ENSMUST00000041005.5
 Fxyd2
FXYD domain-containing ion transport regulator 2
chr5_+_112255813 0.461 ENSMUST00000031286.6
ENSMUST00000131673.1
ENSMUST00000112375.1
 Crybb1


crystallin, beta B1


chr18_+_33464163 0.436 ENSMUST00000097634.3
 Gm10549
predicted gene 10549
chr7_-_141010759 0.421 ENSMUST00000026565.6
 Ifitm3
interferon induced transmembrane protein 3
chr2_+_22622183 0.407 ENSMUST00000028123.3
 Gad2
glutamic acid decarboxylase 2
chr6_-_85933379 0.381 ENSMUST00000162660.1
 Nat8b
N-acetyltransferase 8B
chr9_-_77347787 0.372 ENSMUST00000184848.1
ENSMUST00000184415.1
 Mlip

muscular LMNA-interacting protein

chr6_-_72390659 0.369 ENSMUST00000059983.9
 Vamp8
vesicle-associated membrane protein 8
chr9_-_77347889 0.363 ENSMUST00000185039.1
 Mlip
muscular LMNA-interacting protein
chr2_+_170731807 0.355 ENSMUST00000029075.4
 Dok5
docking protein 5
chr7_+_30184160 0.353 ENSMUST00000098594.2
 Cox7a1
cytochrome c oxidase subunit VIIa 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 67 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 1.0 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.0 1.0 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 1.0 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.7 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.7 GO:0019430 removal of superoxide radicals(GO:0019430)
0.2 0.6 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.2 0.6 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.1 0.4 GO:0090187 zymogen granule exocytosis(GO:0070625) positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.4 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.4 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.3 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.3 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1 0.3 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.1 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 0.3 GO:1905206 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.0 0.3 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.0 0.3 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.7 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.1 0.6 GO:1990357 terminal web(GO:1990357)
0.1 0.6 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.4 GO:0005818 aster(GO:0005818)
0.0 0.4 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.4 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.3 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.2 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0031045 dense core granule(GO:0031045)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 1.0 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 0.8 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.6 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 0.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.4 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.4 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 0.3 GO:0004337 geranyltranstransferase activity(GO:0004337)
0.0 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)