Motif ID: Maff

Z-value: 1.048


Transcription factors associated with Maff:

Gene SymbolEntrez IDGene Name
Maff ENSMUSG00000042622.7 Maff

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Maffmm10_v2_chr15_+_79348061_793481540.621.8e-02Click!


Activity profile for motif Maff.

activity profile for motif Maff


Sorted Z-values histogram for motif Maff

Sorted Z-values for motif Maff



Network of associatons between targets according to the STRING database.



First level regulatory network of Maff

PNG image of the network

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Top targets:


Showing 1 to 20 of 74 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_136886187 7.455 ENSMUST00000046384.8
 C1qb
complement component 1, q subcomponent, beta polypeptide
chr7_-_110862944 7.428 ENSMUST00000033050.3
 Lyve1
lymphatic vessel endothelial hyaluronan receptor 1
chr15_+_3270767 4.590 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chr18_+_33464163 3.663 ENSMUST00000097634.3
 Gm10549
predicted gene 10549
chr13_-_23710714 3.607 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
 Hfe


hemochromatosis


chr11_+_82101836 2.949 ENSMUST00000000194.3
 Ccl12
chemokine (C-C motif) ligand 12
chr17_-_25570678 2.918 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr5_+_104435112 2.263 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
 Spp1





secreted phosphoprotein 1





chr19_+_8929628 1.854 ENSMUST00000096241.4
 Eml3
echinoderm microtubule associated protein like 3
chr13_+_48261427 1.833 ENSMUST00000021810.1
 Id4
inhibitor of DNA binding 4
chr3_+_109573907 1.753 ENSMUST00000106576.2
 Vav3
vav 3 oncogene
chr11_-_109473598 1.639 ENSMUST00000070152.5
 Slc16a6
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr3_-_59262825 1.595 ENSMUST00000050360.7
 P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr7_-_100964371 1.532 ENSMUST00000060174.4
 P2ry6
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr14_+_20929416 1.429 ENSMUST00000022369.7
 Vcl
vinculin
chr4_-_143299498 1.216 ENSMUST00000030317.7
 Pdpn
podoplanin
chr9_-_122310921 1.101 ENSMUST00000180685.1
 Gm26797
predicted gene, 26797
chr14_+_118787894 1.030 ENSMUST00000047761.6
ENSMUST00000071546.7
 Cldn10

claudin 10

chr17_-_67950908 0.983 ENSMUST00000164647.1
 Arhgap28
Rho GTPase activating protein 28
chr19_-_8929323 0.965 ENSMUST00000096242.3
 Rom1
rod outer segment membrane protein 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 31 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.5 GO:0006958 complement activation, classical pathway(GO:0006958)
0.9 7.4 GO:0006027 glycosaminoglycan catabolic process(GO:0006027)
0.7 4.6 GO:0001887 selenium compound metabolic process(GO:0001887)
1.2 3.6 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
1.0 2.9 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
1.0 2.9 GO:0072034 renal vesicle induction(GO:0072034)
0.2 2.3 GO:0033280 response to vitamin D(GO:0033280)
0.2 2.0 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.5 1.8 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
0.1 1.8 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.5 1.6 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 1.6 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.5 1.5 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 1.4 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.3 1.2 GO:1903463 regulation of mitotic cell cycle DNA replication(GO:1903463)
0.2 1.0 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 1.0 GO:0060219 camera-type eye photoreceptor cell differentiation(GO:0060219)
0.2 0.9 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.6 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.5 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)

Gene overrepresentation in cellular_component category:

Showing 1 to 17 of 17 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.5 GO:0005581 collagen trimer(GO:0005581)
0.0 3.8 GO:0045177 apical part of cell(GO:0045177)
0.7 3.6 GO:1990357 terminal web(GO:1990357)
0.0 2.9 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 2.5 GO:0030175 filopodium(GO:0030175)
0.0 1.6 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.4 GO:0005916 fascia adherens(GO:0005916)
0.1 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 0.8 GO:0031262 Ndc80 complex(GO:0031262)
0.1 0.6 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.6 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.2 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.0 0.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 7.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.3 4.6 GO:0008430 selenium binding(GO:0008430)
0.4 3.6 GO:0039706 co-receptor binding(GO:0039706)
0.0 3.2 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.4 3.1 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.7 2.9 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 2.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.2 2.0 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
0.1 1.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.8 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 1.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 1.0 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.6 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.1 0.3 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)