Motif ID: Max_Mycn

Z-value: 1.759

Transcription factors associated with Max_Mycn:

Gene SymbolEntrez IDGene Name
Max ENSMUSG00000059436.6 Max
Mycn ENSMUSG00000037169.8 Mycn

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Maxmm10_v2_chr12_-_76962178_769622480.312.8e-01Click!
Mycnmm10_v2_chr12_-_12940600_12940616-0.195.1e-01Click!


Activity profile for motif Max_Mycn.

activity profile for motif Max_Mycn


Sorted Z-values histogram for motif Max_Mycn

Sorted Z-values for motif Max_Mycn



Network of associatons between targets according to the STRING database.



First level regulatory network of Max_Mycn

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_35119285 2.533 ENSMUST00000042985.9
 Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr11_-_101785252 2.413 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
 Etv4


ets variant gene 4 (E1A enhancer binding protein, E1AF)


chr3_-_95882193 2.385 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
 Gm129


predicted gene 129


chr8_-_45999860 2.147 ENSMUST00000053558.9
 Ankrd37
ankyrin repeat domain 37
chr17_+_45563928 2.079 ENSMUST00000041353.6
 Slc35b2
solute carrier family 35, member B2
chr8_-_105938384 2.032 ENSMUST00000034369.8
 Psmb10
proteasome (prosome, macropain) subunit, beta type 10
chr2_+_121449362 1.903 ENSMUST00000110615.1
ENSMUST00000099475.5
 Serf2

small EDRK-rich factor 2

chr9_-_121495678 1.758 ENSMUST00000035120.4
 Cck
cholecystokinin
chr11_+_102189620 1.725 ENSMUST00000070334.3
ENSMUST00000078975.7
 G6pc3

glucose 6 phosphatase, catalytic, 3

chr10_+_127063599 1.691 ENSMUST00000120226.1
ENSMUST00000133115.1
 Cdk4

cyclin-dependent kinase 4

chr10_+_127063527 1.664 ENSMUST00000006911.5
 Cdk4
cyclin-dependent kinase 4
chr17_-_26201363 1.650 ENSMUST00000121959.1
 Arhgdig
Rho GDP dissociation inhibitor (GDI) gamma
chr12_+_17544873 1.537 ENSMUST00000171737.1
 Odc1
ornithine decarboxylase, structural 1
chr17_-_10320229 1.522 ENSMUST00000053066.6
 Qk
quaking
chr11_+_102881204 1.443 ENSMUST00000021307.3
ENSMUST00000159834.1
 Ccdc103

coiled-coil domain containing 103

chr6_+_7555053 1.431 ENSMUST00000090679.2
ENSMUST00000184986.1
 Tac1

tachykinin 1

chr10_+_77606571 1.429 ENSMUST00000099538.5
 Sumo3
SMT3 suppressor of mif two 3 homolog 3 (yeast)
chr3_-_95882031 1.426 ENSMUST00000161994.1
 Gm129
predicted gene 129
chr15_+_57694651 1.398 ENSMUST00000096430.4
 Zhx2
zinc fingers and homeoboxes 2
chr5_+_28165690 1.392 ENSMUST00000036177.7
 En2
engrailed 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 583 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 4.8 GO:0006414 translational elongation(GO:0006414)
0.8 4.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.8 3.4 GO:0010288 response to lead ion(GO:0010288)
0.1 3.4 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.1 3.0 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.4 2.9 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627)
0.1 2.9 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 2.7 GO:0038092 nodal signaling pathway(GO:0038092)
0.1 2.6 GO:0043489 RNA stabilization(GO:0043489)
0.4 2.5 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.5 2.3 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.6 2.2 GO:0060266 positive regulation of respiratory burst involved in inflammatory response(GO:0060265) negative regulation of respiratory burst involved in inflammatory response(GO:0060266) negative regulation of respiratory burst(GO:0060268)
0.3 2.2 GO:0051503 adenine nucleotide transport(GO:0051503)
0.2 2.2 GO:0046051 UTP metabolic process(GO:0046051)
0.2 2.1 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.1 2.1 GO:0045792 negative regulation of cell size(GO:0045792)
0.2 1.9 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 1.9 GO:0006446 regulation of translational initiation(GO:0006446)
0.2 1.8 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.2 1.8 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 230 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 10.7 GO:0022626 cytosolic ribosome(GO:0022626)
0.2 10.2 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.5 5.2 GO:0005642 annulate lamellae(GO:0005642)
0.1 4.6 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 4.2 GO:0019866 organelle inner membrane(GO:0019866)
0.1 4.0 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 2.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.8 2.5 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 2.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 2.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.5 2.0 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 2.0 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 2.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.0 GO:0001726 ruffle(GO:0001726)
0.3 1.8 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.2 1.8 GO:0070545 PeBoW complex(GO:0070545)
0.2 1.8 GO:0031931 TORC1 complex(GO:0031931)
0.1 1.8 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.1 1.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.7 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 366 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.4 5.5 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.4 5.0 GO:0017070 U6 snRNA binding(GO:0017070)
0.3 4.4 GO:0031386 protein tag(GO:0031386)
0.0 3.9 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 3.9 GO:0003924 GTPase activity(GO:0003924)
0.1 3.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.1 2.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 2.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 2.7 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.2 2.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 2.7 GO:0030332 cyclin binding(GO:0030332)
0.1 2.6 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 2.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.4 2.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 2.5 GO:0051920 peroxiredoxin activity(GO:0051920)
0.1 2.5 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.2 2.4 GO:0015250 water channel activity(GO:0015250)
0.7 2.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.2 2.1 GO:0019203 carbohydrate phosphatase activity(GO:0019203)