Motif ID: Maz_Zfp281

Z-value: 1.536

Transcription factors associated with Maz_Zfp281:

Gene SymbolEntrez IDGene Name
Maz ENSMUSG00000030678.6 Maz
Zfp281 ENSMUSG00000041483.8 Zfp281

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mazmm10_v2_chr7_-_127026479_1270264960.322.7e-01Click!
Zfp281mm10_v2_chr1_+_136624901_1366249490.156.0e-01Click!


Activity profile for motif Maz_Zfp281.

activity profile for motif Maz_Zfp281


Sorted Z-values histogram for motif Maz_Zfp281

Sorted Z-values for motif Maz_Zfp281



Network of associatons between targets according to the STRING database.



First level regulatory network of Maz_Zfp281

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_125532377 3.893 ENSMUST00000031446.6
 Tmem132b
transmembrane protein 132B
chr4_+_97777606 3.582 ENSMUST00000075448.6
ENSMUST00000092532.6
 Nfia

nuclear factor I/A

chr4_+_97777780 3.574 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
 Nfia


nuclear factor I/A


chr8_+_12395287 3.535 ENSMUST00000180353.1
 Sox1
SRY-box containing gene 1
chr18_+_64340225 3.145 ENSMUST00000175965.2
ENSMUST00000115145.3
 Onecut2

one cut domain, family member 2

chr7_-_142657466 3.127 ENSMUST00000097936.2
ENSMUST00000000033.5
 Igf2

insulin-like growth factor 2

chr15_+_57694651 2.869 ENSMUST00000096430.4
 Zhx2
zinc fingers and homeoboxes 2
chr7_-_31042078 2.731 ENSMUST00000162116.1
ENSMUST00000159924.1
ENSMUST00000159753.1
ENSMUST00000160689.1
ENSMUST00000162733.1
ENSMUST00000162087.1
ENSMUST00000009831.7
 Fxyd5






FXYD domain-containing ion transport regulator 5






chr17_+_27029259 2.498 ENSMUST00000053683.6
 Ggnbp1
gametogenetin binding protein 1
chr15_+_32244801 2.480 ENSMUST00000067458.6
 Sema5a
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr2_+_71529085 2.456 ENSMUST00000152711.1
 Dlx1
distal-less homeobox 1
chr2_-_34372004 2.388 ENSMUST00000113132.2
ENSMUST00000040638.8
 Pbx3

pre B cell leukemia homeobox 3

chr1_-_165708088 2.305 ENSMUST00000040357.8
ENSMUST00000097474.3
 Rcsd1

RCSD domain containing 1

chr4_-_25800083 2.260 ENSMUST00000084770.4
 Fut9
fucosyltransferase 9
chr2_-_116065798 2.246 ENSMUST00000110907.1
ENSMUST00000110908.2
 Meis2

Meis homeobox 2

chr1_+_42697146 2.246 ENSMUST00000054883.2
 Pou3f3
POU domain, class 3, transcription factor 3
chr3_+_156561792 2.222 ENSMUST00000074015.4
 Negr1
neuronal growth regulator 1
chr2_-_25470031 2.207 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr16_+_20733104 2.156 ENSMUST00000115423.1
ENSMUST00000007171.6
 Chrd

chordin

chr12_+_33957645 2.124 ENSMUST00000049089.5
 Twist1
twist basic helix-loop-helix transcription factor 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 1,031 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.7 GO:0070208 protein heterotrimerization(GO:0070208)
0.7 5.3 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.4 5.3 GO:0060579 ventral spinal cord interneuron fate commitment(GO:0060579) cell fate commitment involved in pattern specification(GO:0060581)
1.6 4.9 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
1.4 4.1 GO:0090425 hepatocyte cell migration(GO:0002194) branching involved in pancreas morphogenesis(GO:0061114) acinar cell differentiation(GO:0090425) positive regulation of forebrain neuron differentiation(GO:2000979)
0.8 4.0 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.4 4.0 GO:0021796 cerebral cortex regionalization(GO:0021796)
1.3 3.8 GO:0030421 defecation(GO:0030421)
0.4 3.8 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.3 3.5 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.8 3.4 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.3 3.4 GO:1902459 positive regulation of stem cell population maintenance(GO:1902459)
0.1 3.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.8 3.2 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
0.6 3.2 GO:2000325 regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.5 3.2 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.3 3.2 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.2 3.2 GO:0044243 multicellular organism catabolic process(GO:0044243)
0.3 3.1 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
1.0 3.0 GO:0006116 NADH oxidation(GO:0006116)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 316 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 20.4 GO:0005615 extracellular space(GO:0005615)
0.1 18.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 11.5 GO:0005667 transcription factor complex(GO:0005667)
0.2 7.9 GO:0005581 collagen trimer(GO:0005581)
0.2 5.0 GO:0060077 inhibitory synapse(GO:0060077)
0.3 4.8 GO:0071004 U2-type prespliceosome(GO:0071004)
1.4 4.3 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.3 4.0 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.5 3.7 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 3.7 GO:0031225 anchored component of membrane(GO:0031225)
0.1 3.5 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.5 3.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.3 3.2 GO:0001739 sex chromatin(GO:0001739)
0.1 3.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.1 2.9 GO:0031012 extracellular matrix(GO:0031012)
0.0 2.8 GO:0072562 blood microparticle(GO:0072562)
0.0 2.8 GO:0005924 cell-substrate adherens junction(GO:0005924)
0.9 2.7 GO:0005584 collagen type I trimer(GO:0005584)
0.6 2.5 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.2 2.5 GO:0005885 Arp2/3 protein complex(GO:0005885)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 517 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 31.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 11.8 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 8.6 GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding(GO:0000977)
0.3 7.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 6.3 GO:0017091 AU-rich element binding(GO:0017091)
0.1 6.1 GO:0000982 transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0000982)
0.1 5.8 GO:0008201 heparin binding(GO:0008201)
0.3 5.5 GO:0001848 complement binding(GO:0001848)
0.4 4.7 GO:0048407 platelet-derived growth factor binding(GO:0048407)
1.1 4.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 4.2 GO:0051183 vitamin transporter activity(GO:0051183)
0.5 4.1 GO:0050693 LBD domain binding(GO:0050693)
0.1 4.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 3.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.2 3.8 GO:0015026 coreceptor activity(GO:0015026)
0.1 3.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 3.6 GO:0003729 mRNA binding(GO:0003729)
0.5 3.4 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.1 3.4 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.8 3.3 GO:0015185 gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)