Motif ID: Mef2b

Z-value: 0.831


Transcription factors associated with Mef2b:

Gene SymbolEntrez IDGene Name
Mef2b ENSMUSG00000079033.3 Mef2b

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mef2bmm10_v2_chr8_+_70152754_701527810.097.7e-01Click!


Activity profile for motif Mef2b.

activity profile for motif Mef2b


Sorted Z-values histogram for motif Mef2b

Sorted Z-values for motif Mef2b



Network of associatons between targets according to the STRING database.



First level regulatory network of Mef2b

PNG image of the network

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Top targets:


Showing 1 to 20 of 173 entries
PromoterScoreRefseqGene SymbolGene Name
chrY_-_1286563 5.410 ENSMUST00000091190.5
 Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr5_-_128953303 1.128 ENSMUST00000111346.1
 Rimbp2
RIMS binding protein 2
chr9_+_34904913 1.021 ENSMUST00000045091.6
 Kirrel3
kin of IRRE like 3 (Drosophila)
chr18_-_25753852 0.899 ENSMUST00000025117.6
ENSMUST00000115816.2
 Celf4

CUGBP, Elav-like family member 4

chr13_-_67081503 0.812 ENSMUST00000109742.3
 Zfp708
zinc finger protein 708
chr3_+_103279293 0.709 ENSMUST00000029444.6
ENSMUST00000106860.1
 Trim33

tripartite motif-containing 33

chrX_+_159303266 0.677 ENSMUST00000112491.1
 Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr2_-_79908428 0.671 ENSMUST00000102652.3
ENSMUST00000102651.3
 Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr7_+_81862674 0.648 ENSMUST00000119543.1
 Tm6sf1
transmembrane 6 superfamily member 1
chr8_-_77610668 0.611 ENSMUST00000141202.1
ENSMUST00000152168.1
 Tmem184c

transmembrane protein 184C

chr12_+_71048338 0.607 ENSMUST00000135709.1
 Arid4a
AT rich interactive domain 4A (RBP1-like)
chr5_+_104508338 0.601 ENSMUST00000096452.4
 BC005561
cDNA sequence BC005561
chr3_+_14533817 0.561 ENSMUST00000169079.1
ENSMUST00000091325.3
 Lrrcc1

leucine rich repeat and coiled-coil domain containing 1

chr10_+_119992962 0.558 ENSMUST00000154238.1
 Grip1
glutamate receptor interacting protein 1
chr2_-_57124003 0.553 ENSMUST00000112629.1
 Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr6_+_48589560 0.541 ENSMUST00000181661.1
 Gm5111
predicted gene 5111
chr13_-_23934156 0.528 ENSMUST00000052776.2
 Hist1h2ba
histone cluster 1, H2ba
chr16_+_4968936 0.527 ENSMUST00000090457.5
 4930451G09Rik
RIKEN cDNA 4930451G09 gene
chr1_-_172329261 0.523 ENSMUST00000062387.2
 Kcnj9
potassium inwardly-rectifying channel, subfamily J, member 9
chr18_+_23954668 0.507 ENSMUST00000060762.4
 Zfp397
zinc finger protein 397

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 55 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.5 GO:0046069 cGMP catabolic process(GO:0046069)
0.2 1.0 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.2 0.9 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.9 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.0 0.9 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.2 0.8 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.1 0.8 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.2 0.7 GO:1990481 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) snRNA pseudouridine synthesis(GO:0031120) mRNA pseudouridine synthesis(GO:1990481)
0.0 0.7 GO:0016601 Rac protein signal transduction(GO:0016601)
0.1 0.6 GO:0051866 general adaptation syndrome(GO:0051866)
0.1 0.6 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.1 0.5 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.1 0.5 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.5 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.5 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.5 GO:0010107 potassium ion import(GO:0010107)
0.1 0.4 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.4 GO:0042908 xenobiotic transport(GO:0042908)
0.1 0.4 GO:0030644 cellular chloride ion homeostasis(GO:0030644)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 5.4 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)
0.0 1.0 GO:0043198 dendritic shaft(GO:0043198)
0.1 0.8 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.8 GO:0043196 varicosity(GO:0043196)
0.2 0.7 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.7 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.5 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.4 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.1 0.3 GO:0090537 CERF complex(GO:0090537)
0.1 0.3 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.3 GO:0005833 hemoglobin complex(GO:0005833)
0.0 0.3 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176) cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.1 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0043083 synaptic cleft(GO:0043083)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.4 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.2 1.5 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 1.2 GO:0017022 myosin binding(GO:0017022)
0.1 0.9 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.9 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 0.9 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 0.8 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.2 0.7 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.7 GO:0070410 co-SMAD binding(GO:0070410)
0.2 0.6 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.6 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.1 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 0.4 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 0.4 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 0.4 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.4 GO:0035035 histone acetyltransferase binding(GO:0035035)
0.1 0.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.3 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.1 0.3 GO:0031721 hemoglobin alpha binding(GO:0031721)