Motif ID: Meis1

Z-value: 0.905


Transcription factors associated with Meis1:

Gene SymbolEntrez IDGene Name
Meis1 ENSMUSG00000020160.12 Meis1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meis1mm10_v2_chr11_-_19018714_190188280.391.7e-01Click!


Activity profile for motif Meis1.

activity profile for motif Meis1


Sorted Z-values histogram for motif Meis1

Sorted Z-values for motif Meis1



Network of associatons between targets according to the STRING database.



First level regulatory network of Meis1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_136892867 3.237 ENSMUST00000046332.5
 C1qc
complement component 1, q subcomponent, C chain
chr1_+_178529113 2.743 ENSMUST00000161017.1
 Kif26b
kinesin family member 26B
chr3_-_87263518 2.135 ENSMUST00000090986.4
 Fcrls
Fc receptor-like S, scavenger receptor
chr3_-_87263703 1.735 ENSMUST00000146512.1
 Fcrls
Fc receptor-like S, scavenger receptor
chr10_-_128744014 1.310 ENSMUST00000026414.7
 Dgka
diacylglycerol kinase, alpha
chr11_-_42182163 1.244 ENSMUST00000153147.1
 Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr2_-_113758638 1.239 ENSMUST00000099575.3
 Grem1
gremlin 1
chr3_+_134828993 1.204 ENSMUST00000029822.4
 Tacr3
tachykinin receptor 3
chrY_+_90755657 1.148 ENSMUST00000167967.2
 Gm21857
predicted gene, 21857
chr8_+_70501116 1.123 ENSMUST00000127983.1
 Crlf1
cytokine receptor-like factor 1
chr14_-_30008817 1.003 ENSMUST00000122205.1
ENSMUST00000016110.6
 Il17rb

interleukin 17 receptor B

chr8_+_127064107 0.967 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
 Pard3








par-3 (partitioning defective 3) homolog (C. elegans)








chr19_-_28680077 0.940 ENSMUST00000162022.1
ENSMUST00000112612.2
 Glis3

GLIS family zinc finger 3

chr8_+_127064022 0.934 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
 Pard3


par-3 (partitioning defective 3) homolog (C. elegans)


chr18_+_56432116 0.908 ENSMUST00000070166.5
 Gramd3
GRAM domain containing 3
chr17_-_35175995 0.870 ENSMUST00000173324.1
 Aif1
allograft inflammatory factor 1
chr6_-_36811361 0.861 ENSMUST00000101534.1
 Ptn
pleiotrophin
chr15_-_26895049 0.824 ENSMUST00000059204.9
 Fbxl7
F-box and leucine-rich repeat protein 7
chr12_+_91400990 0.762 ENSMUST00000021346.7
ENSMUST00000021343.6
 Tshr

thyroid stimulating hormone receptor

chr1_-_64956731 0.761 ENSMUST00000123225.1
 Plekhm3
pleckstrin homology domain containing, family M, member 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 3.2 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.9 2.7 GO:0072092 ureteric bud invasion(GO:0072092)
0.3 1.9 GO:0003383 apical constriction(GO:0003383)
0.4 1.2 GO:1901228 regulation of osteoclast proliferation(GO:0090289) negative regulation of bone mineralization involved in bone maturation(GO:1900158) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.2 1.2 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 1.2 GO:0071420 cellular response to histamine(GO:0071420)
0.2 1.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 1.1 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0 1.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.3 0.9 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.3 0.9 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 0.8 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.1 0.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 0.6 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.6 GO:0001504 neurotransmitter uptake(GO:0001504)
0.1 0.5 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.5 GO:0015793 glycerol transport(GO:0015793)
0.1 0.5 GO:0045059 positive thymic T cell selection(GO:0045059)
0.0 0.5 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 3.2 GO:0005581 collagen trimer(GO:0005581)
0.0 2.4 GO:0005871 kinesin complex(GO:0005871)
0.2 1.9 GO:0033269 internode region of axon(GO:0033269)
0.0 1.7 GO:0044298 cell body membrane(GO:0044298)
0.1 1.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.4 1.1 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 0.9 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.9 GO:0031594 neuromuscular junction(GO:0031594)
0.2 0.7 GO:0016012 sarcoglycan complex(GO:0016012)
0.0 0.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.7 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.4 GO:0071953 elastic fiber(GO:0071953)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 0.3 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.3 GO:0034451 centriolar satellite(GO:0034451)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 2.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 2.0 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 1.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 1.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.1 1.2 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 1.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 1.0 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.3 0.9 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.8 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.7 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.1 0.5 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.5 GO:0070412 R-SMAD binding(GO:0070412)
0.1 0.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.4 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)