Motif ID: Meis2

Z-value: 1.696


Transcription factors associated with Meis2:

Gene SymbolEntrez IDGene Name
Meis2 ENSMUSG00000027210.14 Meis2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meis2mm10_v2_chr2_-_116065047_116065133-0.563.9e-02Click!


Activity profile for motif Meis2.

activity profile for motif Meis2


Sorted Z-values histogram for motif Meis2

Sorted Z-values for motif Meis2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meis2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_49822710 3.767 ENSMUST00000031843.6
 Npy
neuropeptide Y
chr19_-_57197496 3.618 ENSMUST00000111544.1
 Ablim1
actin-binding LIM protein 1
chr19_-_57197435 3.537 ENSMUST00000111550.1
 Ablim1
actin-binding LIM protein 1
chr19_-_57197377 3.491 ENSMUST00000111546.1
 Ablim1
actin-binding LIM protein 1
chr3_-_82074639 3.397 ENSMUST00000029635.8
 Gucy1b3
guanylate cyclase 1, soluble, beta 3
chr9_-_63711969 3.284 ENSMUST00000154323.1
 Smad3
SMAD family member 3
chr5_-_25498748 2.979 ENSMUST00000173174.1
 Kmt2c
lysine (K)-specific methyltransferase 2C
chr10_-_29535857 2.849 ENSMUST00000092623.3
 Rspo3
R-spondin 3 homolog (Xenopus laevis)
chr14_-_54870913 2.818 ENSMUST00000146642.1
 Homez
homeodomain leucine zipper-encoding gene
chr19_-_57197556 2.686 ENSMUST00000099294.2
 Ablim1
actin-binding LIM protein 1
chr17_+_21423227 2.515 ENSMUST00000165230.1
ENSMUST00000007884.8
ENSMUST00000167749.1
 Zfp54


zinc finger protein 54


chr3_-_127499095 2.356 ENSMUST00000182594.1
 Ank2
ankyrin 2, brain
chr2_+_158667119 2.325 ENSMUST00000045503.4
 Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr17_+_8924109 2.274 ENSMUST00000149440.1
 Pde10a
phosphodiesterase 10A
chr6_-_121081589 2.255 ENSMUST00000077159.5
 Mical3
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr3_-_67375163 2.216 ENSMUST00000166353.1
 Gm17402
predicted gene, 17402
chr11_+_117986292 2.164 ENSMUST00000132676.1
 Pgs1
phosphatidylglycerophosphate synthase 1
chr7_+_48959089 2.147 ENSMUST00000183659.1
 Nav2
neuron navigator 2
chr4_+_42922253 2.137 ENSMUST00000139100.1
 N28178
expressed sequence N28178
chr13_-_41079628 2.133 ENSMUST00000165087.1
ENSMUST00000070193.6
 Mak

male germ cell-associated kinase


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 140 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 12.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 5.1 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 4.2 GO:0006376 mRNA splice site selection(GO:0006376)
1.0 4.0 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.8 3.8 GO:0019732 antifungal humoral response(GO:0019732)
0.2 3.4 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
1.1 3.3 GO:0044413 evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.2 3.1 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 3.0 GO:0007266 Rho protein signal transduction(GO:0007266)
0.1 2.9 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 2.9 GO:0008643 carbohydrate transport(GO:0008643)
0.4 2.8 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 2.5 GO:0098656 anion transmembrane transport(GO:0098656)
0.3 2.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 2.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 2.3 GO:0030042 actin filament depolymerization(GO:0030042)
0.5 2.1 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
0.4 2.1 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 2.1 GO:2000171 negative regulation of dendrite development(GO:2000171)
0.3 2.0 GO:0015808 L-alanine transport(GO:0015808)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 63 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 14.1 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.4 5.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 4.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 4.0 GO:0043204 perikaryon(GO:0043204)
0.0 3.4 GO:0000139 Golgi membrane(GO:0000139)
0.7 3.3 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.3 3.0 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.1 2.8 GO:0001891 phagocytic cup(GO:0001891)
0.2 2.6 GO:0097542 ciliary tip(GO:0097542)
0.1 2.4 GO:0031430 M band(GO:0031430)
0.2 2.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 1.9 GO:1990391 DNA repair complex(GO:1990391)
0.4 1.8 GO:0008537 proteasome activator complex(GO:0008537)
0.0 1.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.3 1.6 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.5 1.5 GO:0034455 t-UTP complex(GO:0034455)
0.1 1.5 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 1.5 GO:0032590 dendrite membrane(GO:0032590)
0.1 1.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 1.3 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 106 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 13.6 GO:0003779 actin binding(GO:0003779)
0.3 5.9 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 4.0 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.2 3.8 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.2 3.5 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.1 3.5 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.7 3.3 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.3 3.0 GO:0004383 guanylate cyclase activity(GO:0004383)
0.1 2.8 GO:0005109 frizzled binding(GO:0005109)
0.1 2.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 2.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 2.4 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 2.4 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 2.3 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.1 2.3 GO:0030553 cGMP binding(GO:0030553)
0.0 2.2 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.1 2.1 GO:0030515 snoRNA binding(GO:0030515)
0.0 2.1 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.7 2.0 GO:0015173 hydrogen:amino acid symporter activity(GO:0005280) aromatic amino acid transmembrane transporter activity(GO:0015173)
0.6 1.8 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923) oncostatin-M receptor activity(GO:0004924)