Motif ID: Meox2

Z-value: 1.142


Transcription factors associated with Meox2:

Gene SymbolEntrez IDGene Name
Meox2 ENSMUSG00000036144.5 Meox2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Meox2mm10_v2_chr12_+_37108533_37108546-0.068.4e-01Click!


Activity profile for motif Meox2.

activity profile for motif Meox2


Sorted Z-values histogram for motif Meox2

Sorted Z-values for motif Meox2



Network of associatons between targets according to the STRING database.



First level regulatory network of Meox2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 159 entries
PromoterScoreRefseqGene SymbolGene Name
chr14_+_25980039 5.946 ENSMUST00000173155.1
 Duxbl1
double homeobox B-like 1
chr14_+_26119811 5.298 ENSMUST00000173617.1
 Duxbl2
doubl homeobox B-like 2
chr16_+_42907563 5.072 ENSMUST00000151244.1
ENSMUST00000114694.2
 Zbtb20

zinc finger and BTB domain containing 20

chr14_+_26259109 3.608 ENSMUST00000174494.1
 Duxbl3
double homeobox B-like 3
chr13_+_104229366 3.259 ENSMUST00000022227.6
 Cenpk
centromere protein K
chr8_-_46294592 3.013 ENSMUST00000058636.7
 Helt
helt bHLH transcription factor
chr6_+_124304646 2.442 ENSMUST00000112541.2
ENSMUST00000032234.2
 Cd163

CD163 antigen

chr8_+_66386292 2.411 ENSMUST00000039540.5
ENSMUST00000110253.2
 March1

membrane-associated ring finger (C3HC4) 1

chr3_+_66219909 2.226 ENSMUST00000029421.5
 Ptx3
pentraxin related gene
chrM_+_7759 2.152 ENSMUST00000082407.1
ENSMUST00000082408.1
 mt-Atp8
mt-Atp6
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr8_+_12395287 2.084 ENSMUST00000180353.1
 Sox1
SRY-box containing gene 1
chrM_+_10167 1.990 ENSMUST00000082414.1
 mt-Nd4
mitochondrially encoded NADH dehydrogenase 4
chr3_+_103739366 1.926 ENSMUST00000106852.1
 Gm10964
predicted gene 10964
chr3_-_98339921 1.919 ENSMUST00000065793.5
 Phgdh
3-phosphoglycerate dehydrogenase
chrM_-_14060 1.698 ENSMUST00000082419.1
 mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr14_+_25979401 1.602 ENSMUST00000173580.1
 Duxbl1
double homeobox B-like 1
chr18_+_12972225 1.509 ENSMUST00000025290.5
 Impact
imprinted and ancient
chr2_+_26581050 1.475 ENSMUST00000166920.2
 Egfl7
EGF-like domain 7
chr19_+_59458372 1.425 ENSMUST00000062216.3
 Emx2
empty spiracles homeobox 2
chr14_-_16575456 1.399 ENSMUST00000063750.6
 Rarb
retinoic acid receptor, beta

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.5 GO:0045580 regulation of T cell differentiation(GO:0045580)
0.1 5.1 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.2 3.4 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.2 3.0 GO:0097154 GABAergic neuron differentiation(GO:0097154)
0.1 2.4 GO:0006953 acute-phase response(GO:0006953)
0.7 2.2 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 2.1 GO:0021521 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.1 2.1 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.6 1.9 GO:0006566 threonine metabolic process(GO:0006566)
0.1 1.9 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 1.6 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.5 1.5 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.0 1.5 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
0.3 1.4 GO:0030091 protein repair(GO:0030091)
0.2 1.4 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 1.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.1 1.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.2 1.0 GO:0033762 response to glucagon(GO:0033762)
0.2 0.9 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.1 0.9 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.5 GO:0070469 respiratory chain(GO:0070469)
0.0 3.1 GO:0000776 kinetochore(GO:0000776)
0.1 2.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.2 1.9 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.5 GO:0005844 polysome(GO:0005844)
0.0 1.4 GO:0000786 nucleosome(GO:0000786)
0.2 0.9 GO:0097149 centralspindlin complex(GO:0097149)
0.1 0.9 GO:0045275 respiratory chain complex III(GO:0045275)
0.2 0.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.2 0.8 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.8 GO:0005776 autophagosome(GO:0005776)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.1 0.5 GO:0070552 BRISC complex(GO:0070552)
0.1 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.4 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.4 GO:0030478 actin cap(GO:0030478)
0.1 0.3 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.1 0.3 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 36 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 6.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 2.4 GO:0042287 MHC protein binding(GO:0042287)
0.1 2.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.4 2.2 GO:0001849 complement component C1q binding(GO:0001849)
0.0 2.1 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 1.9 GO:0051287 NAD binding(GO:0051287)
0.0 1.6 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.5 GO:0005112 Notch binding(GO:0005112)
0.0 1.5 GO:0043022 ribosome binding(GO:0043022)
0.2 1.4 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.1 1.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 1.4 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.4 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.1 0.9 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.8 GO:0032183 SUMO binding(GO:0032183)
0.0 0.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.8 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 0.8 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)